Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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The involvement of LEF1/TCF transcription factors in astrogenesis

2017/24/C/NZ3/00447

Keywords:

transcription factors LEF1/TCF astrocyte neuroepithelial cell astrogenesis

Descriptors:

  • NZ3_1: Cell biology
  • NZ3_5: Molecular neurobiology
  • NZ3_6: Cell neurobiology

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Łukasz Szewczyk 

Number of co-investigators in the project: 1

Call: SONATINA 1 - announced on 2016-12-15

Amount awarded: 831 311 PLN

Project start date (Y-m-d): 2017-10-16

Project end date (Y-m-d): 2021-01-15

Project duration:: 39 months (the same as in the proposal)

Project status: Project settled

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (2)
  • Book publications / chapters in book publications (1)
  1. Wnt/β-catenin signaling in brain development and mental disorders: keeping TCF7L2 in mind.
    Authors:
    Bem Joanna, Brożko Nikola, Chakraborty Chaitali, Lipiec Marcin, Koziński Kamil, Nagalski Andrzej, Szewczyk Łukasz, Wiśniewska Marta.
    Academic press:
    FEBS Lett. (rok: 2019, tom: 13, strony: 1654-1674), Wydawca: John Wiley & Sons Ltd
    Status:
    Published
    DOI:
    10.1002/1873-3468.13502. - link to the publication
  2. Astrocytic β-catenin signaling via TCF7L2 regulates synapse development and social behavior.
    Authors:
    Lukasz Szewczyk, Marcin Lipiec, Ewa Liszewska, Ksenia Meyza, Joanna Urban-Ciecko, Ludwika Kondrakiewicz, Anna Goncerzewicz, Kamil Rafalko, Tomasz Krawczyk, Karolina Bogaj, Ilia Vainchtein, Hiromi Nakao-Inoue, Alicja Puscian, Ewelina Knapska, Stephan Sanders, Tomasz Nowakowski, Anna Victoria Molofsky, and Marta Wisniewska
    Academic press:
    Molecular Psychiatry , Wydawca: Springer Nature
    Status:
    Accepted for publication
    DOI:
    brak - link to the publication
  1. Mechanisms of astrocyte development
    Authors:
    Sardar D, Cheng YT, Szewczyk LM, Deneen B, Molofsky AV
    Book:
    Patterning and Cell Type Specification in the Developing CNS and PNS (Second Edition), Comprehensive Developmental Neuroscience (rok: 2020, tom: III, strony: 807-827), Wydawca: Elsevier Inc.
    Status:
    Published

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