Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Epigentic regulation of EDC cluster gene expression in keratinocyte differentiation

2016/23/N/NZ2/02376

Keywords:

epidermal differentiation complex keratinocytes histone modifications differentiation CRISPR/Cas9 knockout silencing

Descriptors:

  • NZ2_2: Genomics, transcriptomics, epigenomics

Panel:

NZ2 - Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology

Host institution :

Instytut Biologii Doświadczalnej im. M. Nenckiego Polskiej Akademii Nauk

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Barbara Sobiak 

Number of co-investigators in the project: 2

Call: PRELUDIUM 12 - announced on 2016-09-15

Amount awarded: 100 000 PLN

Project start date (Y-m-d): 2017-07-12

Project end date (Y-m-d): 2019-07-11

Project duration:: 24 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Cyfrowy licznik komórek (14 000 PLN)
  2. Termomikser VWR Lite.

Information in the final report

  • Publication in academic press/journals (2)
  1. The Effect of Single CpG Demethylation on the Pattern of DNA-Protein Binding
    Authors:
    Sobiak Barbara, Leśniak Wiesława
    Academic press:
    International Journal of Molecular Sciences (rok: 2019, tom: 20, strony: brak), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms20040914. - link to the publication
  2. S100A6 activates EGFR and its downstream signaling in HaCaT keratinocytes
    Authors:
    Agnieszka Graczyk Jarzynka, Barbara Sobiak, Michał Mlącki, Tomasz Wilanowski, Wiesława Leśniak
    Academic press:
    Journal of Cellular Physiology (rok: 2019, tom: brak, strony: brak), Wydawca: Wiley Online Library
    Status:
    Published
    DOI:
    10.1002/jcp.28379 - link to the publication