Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Assessment of immune system with reference to clinical status in patients with viral hepatitis C subjected to interferon-free therapy.

2016/23/B/NZ6/01497

Keywords:

infectious diseases viral hepatitis C directly acting antivirals

Descriptors:

  • NZ6_2: Clinical immunology
  • NZ6_5: Virology
  • NZ6_1: Adaptive and innate immunity

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Medyczny

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Iwona Mozer-Lisewska 

Number of co-investigators in the project: 7

Call: OPUS 12 - announced on 2016-09-15

Amount awarded: 1 528 300 PLN

Project start date (Y-m-d): 2017-08-29

Project end date (Y-m-d): 2021-08-28

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. FibroScan 530 Compact z głowicą M i XL, systemem CAP i wózkiem transportowym + wsparcie STANDARD (36 miesięcy) (500 000 PLN)

Information in the final report

  • Publication in academic press/journals (5)
  1. Treg cells in the course of chronic hepatitis C virus infection partially normalize in longitudinal observation after successful DAA treatment regardless of hepatic fibrosis stage
    Authors:
    Agata Zientarska, Mariusz Kaczmarek, Iwona Mozer-Lisewska, Arleta Kowala-Piaskowska, Aleksandra Witkowska, Jan Żeromski
    Academic press:
    Clinical and Experimental Hepatology (rok: 2021, tom: 7, strony: 196-204), Wydawca: Temedia
    Status:
    Published
    DOI:
    10.5114/ceh.2021.107122 - link to the publication
  2. Significance and role of pattern recognition receptors in malignancy
    Authors:
    Jan Żeromski, Mariusz Kaczmarek , Maciej Boruczkowski , Agata Kierepa, Arleta Kowala-Piaskowska, Iwona Mozer-Lisewska
    Academic press:
    Archivum Immunologiae et Therapiae Experimentalis (rok: 2019, tom: 67, strony: 133-141), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s00005-019-00540-x - link to the publication
  3. Impact of chronic HCV treatment on quality of life of patients with metabolic disorders in context of immunological disturbances
    Authors:
    Agata Kierepa, Aleksandra Witkowska, Mariusz Kaczmarek, Krzysztof Książek, Justyna Mikuła-Pietrasik, Jan Żeromski, Arleta Kowala-Piaskowska, Iwona Mozer-Lisewska.
    Academic press:
    Scientific Reports (rok: 2020, tom: 10, strony: 10388), Wydawca: Nature Publishing Group
    Status:
    Published
    DOI:
    10.1038/s41598-020-67296-9 - link to the publication
  4. PATTERN RECOGNITION RECEPTORS: SIGNIFICANCE OF EXPRESSION IN LIVER
    Authors:
    Jan Żeromski, Agata Kierepa, Arleta Kowala-Piaskowska, Iwona Mozer-Lisewska
    Academic press:
    Archivum Immunologiae et Therapiae Experimentalis (rok: 2020, tom: 68, strony: 29), Wydawca: Springer International Publishing
    Status:
    Published
    DOI:
    10.1007/s00005-020-00595-1. - link to the publication
  5. Gender as a factor affecting the NK cell activity in patients successfully treated for chronic hepatitis C with DAA
    Authors:
    Agata Zientarska, Justyna Mikuła-Pietrasik, Mariusz Kaczmarek, Aleksandra Witkowska, Błażej Rozpłochowski, Arleta Kowala-Piaskowska, Krzysztof Książek, Jan Żeromski, Iwona Mozer-Lisewska
    Academic press:
    Central European Journal of Immunology (rok: 2021, tom: 46, strony: ), Wydawca: Termedia
    Status:
    Accepted for publication
    DOI:
    10.5114/ceji.2021.109846 - link to the publication