Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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SLPI - novel regulator involved in the neuro-immune interplay in psoriasis

2016/23/D/NZ6/00102

Keywords:

secretory leukocyte protease inhibitor (SLPI) neurogenic inflammation skin psoriasis mast cells NGF

Descriptors:

  • NZ6_8: Other related subjects

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Beata Grygier 

Number of co-investigators in the project: 4

Call: SONATA 12 - announced on 2016-09-15

Amount awarded: 742 200 PLN

Project start date (Y-m-d): 2017-08-02

Project end date (Y-m-d): 2023-02-01

Project duration:: 66 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. sterylizator kulkowy.
  2. mikroskop stereoskopowy (12 000 PLN)
  3. homogenizator tkanek (10 000 PLN)

Information in the final report

  • Publication in academic press/journals (1)
  • Articles in post-conference publications (2)
  1. Secretory leukocyte protease inhibitor modulates FcRI-dependent but not Mrgprb2- dependent mastocyte function in psoriasis.
    Authors:
    Patrycja Kwiecinska, Mateusz Kwitniewski, Kamila Kwiecień, Agnieszka Morytko, Pawel Majewski, Natalia Pocalun, Maciej Pastuszczak, Marcin Migaczewski, Joanna Cichy, Beata Grygier
    Academic press:
    International Immunopharmacology (rok: 2023, tom: 122, strony: 45300), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.intimp.2023.110631 - link to the publication
  1. Considering the role of brain neutrophils in psoriasis – relationship between peripheral autoinflammation and central nervous system
    Authors:
    Beata Grygier, Patrycja Kwiecinska, Kamila Kwiecien, Alicja Uchanska
    Conference:
    15th International Congress of Neuroimmunology 3rd Global Schools of Neuroimmunology Pre-Course (rok: 2021, ), Wydawca: International Society of Neuroimmunology
    Data:
    konferencja 8-12 November 2021
    Status:
    Published
  2. Rearrangement of brain myeloid cell population during psoriatic-like skin inflammation
    Authors:
    Beata Grygier, Patrycja Kwiecinska, Alicja Uchanska, Kamila Kwiecień
    Conference:
    European Molecular Biology Organization (EMBO) Workshop: Microglia 2021 (rok: 2021, ), Wydawca: European Molecular Biology Organization (EMBO)
    Data:
    konferencja 28 - 29 October 2021
    Status:
    Published