Identification of obesity risk variants in the dog genome using whole-genome sequencing

2016/23/B/NZ2/01762

Keywords

Descriptors

  • NZ2_1: Genetyka molekularna
  • NZ2_7: Bioinformatyka

Panel

NZ2 – Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology

Host institution

Uniwersytet Przyrodniczy w Poznaniu, Wydział Medycyny Weterynaryjnej i Nauk o Zwierzętach

Voivodeship: wielkopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

prof. Maciej Szydłowski

Number of co-investigators in the project: 5

Call

OPUS 12 – announced on 2016-09-15

Amount awarded
1 132 100 PLN
Project start date
2017-08-04
Project end date
2022-08-03
Project duration
60 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Aparat do ddPCR. Cost: 350 000 PLN
  2. Serwer obliczeniowy z dyskami do przechowywania danych i oprogramowanie. Cost: 45 000 PLN

Information in the final report

Publication in academic press/journals (4)

  1. No association between AMY2B gene copy number and obesity risk in Labrador retriever dogs

    Authors:
    Michal Antkowiak, Izabela Szczerbal, Joanna Nowacka‐Woszuk, Marek Switonski, Maciej Szydlowski
    Academic press:
    Animal Genetics (year: 2019, volume: 50, pages: 552-553), Publisher: Blackwell Publishing
    Status:
    Published
    DOI:
    10.1111/age.12824 – link to the publication
  2. No evidence that long runs of homozygosity tend to harbor risk variants for polygenic obesity in Labrador retriever dogs.

    Authors:
    Szydlowski M., Antkowiak M.
    Academic press:
    Journal of Applied Genetics (year: 2022, volume: 63, pages: 557–561), Publisher: Springer
    Status:
    Published
    DOI:
    10.1007/s13353-022-00693-0 – link to the publication
  3. A study of 41 canine orthologues of human genes involved in monogenic obesity reveals marker in the ADCY3 for body weight in Labrador Retrievers

    Authors:
    Mateusz Sypniewski, Maciej Szydłowski
    Academic press:
    Veterinary Sciences (year: 2023, volume: 0,6875, pages: 0,6875), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/vetsci10060390 – link to the publication
  4. Uncovering structural variants associated with body weight and obesity risk in labrador retrievers: a genome-wide study

    Authors:
    Michał Antkowiak, Maciej Szydłowski
    Academic press:
    Frontiers in Genetics (year: 2023, volume: 14:1235821, pages: 14:1235821), Publisher: Frontiers
    Status:
    Published
    DOI:
    10.3389/fgene.2023.1235821 – link to the publication

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