Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Identification of obesity risk variants in the dog genome using whole-genome sequencing

2016/23/B/NZ2/01762

Keywords:

dog obesity CNV SNP indel NGS ddPCR

Descriptors:

  • NZ2_1: Molecular genetics
  • NZ2_7: Bioinformatics

Panel:

NZ2 - Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology

Host institution :

Uniwersytet Przyrodniczy w Poznaniu, Wydział Medycyny Weterynaryjnej i Nauk o Zwierzętach

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Maciej Szydłowski 

Number of co-investigators in the project: 5

Call: OPUS 12 - announced on 2016-09-15

Amount awarded: 1 132 100 PLN

Project start date (Y-m-d): 2017-08-04

Project end date (Y-m-d): 2022-08-03

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Aparat do ddPCR (350 000 PLN)
  2. Serwer obliczeniowy z dyskami do przechowywania danych i oprogramowanie (45 000 PLN)

Information in the final report

  • Publication in academic press/journals (5)
  1. A study of 41 canine orthologues of human genes involved in monogenic obesity reveals marker in the ADCY3 for body weight in Labrador Retrievers
    Authors:
    Mateusz Sypniewski, Maciej Szydłowski
    Academic press:
    Veterinary Sciences (rok: 2023, tom: 0,6875, strony: 0,6875), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/vetsci10060390 - link to the publication
  2. Uncovering structural variants associated with body weight and obesity risk in labrador retrievers: a genome-wide study
    Authors:
    Michał Antkowiak, Maciej Szydłowski
    Academic press:
    Frontiers in Genetics (rok: 2023, tom: 14:1235821, strony: 14:1235821), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fgene.2023.1235821 - link to the publication
  3. No association between AMY2B gene copy number and obesity risk in Labrador retriever dogs
    Authors:
    Michal Antkowiak, Izabela Szczerbal, Joanna Nowacka‐Woszuk, Marek Switonski, Maciej Szydlowski
    Academic press:
    Animal Genetics (rok: 2019, tom: 50, strony: 552-553), Wydawca: Blackwell Publishing
    Status:
    Published
    DOI:
    10.1111/age.12824 - link to the publication
  4. No evidence that long runs of homozygosity tend to harbor risk variants for polygenic obesity in Labrador retriever dogs.
    Authors:
    Szydlowski M., Antkowiak M.
    Academic press:
    Journal of Applied Genetics (rok: 2022, tom: 63, strony: 557–561), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s13353-022-00693-0 - link to the publication
  5. Variants in ADCY3 gene are associated with body condition score in Labrador Retrievers
    Authors:
    Mateusz Sypniewski, Maciej Szydłowski
    Academic press:
    Polish Journal of Veterinary Sciences , Wydawca: Polish Academy of Sciences Committee of Veterinary Sciences, University of Warmia and Mazury in Olsztyn
    Status:
    Submitted
    DOI:
    brak - link to the publication

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