Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Mechanisms of global interplay between bacterial stress response, DNA replication and metabolism in Escherichia coli

2016/23/D/NZ1/02601

Keywords:

ppGpp DNA replication metabolism central carbon metabolism

Descriptors:

  • NZ1_1: Molecular biology
  • NZ1_2: Biochemistry
  • NZ1_10: Microbiology

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Uniwersytet Gdański, Wydział Biologii

woj. pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Monika Maciąg-Dorszyńska 

Number of co-investigators in the project: 2

Call: SONATA 12 - announced on 2016-09-15

Amount awarded: 678 200 PLN

Project start date (Y-m-d): 2017-07-13

Project end date (Y-m-d): 2023-07-12

Project duration:: 72 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Ekran do urządzenia fosfo-imager (40 000 PLN)
  2. Termomikser (15 000 PLN)
  3. Wytrząsarka (20 000 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  1. The Role of Metabolites in the Link between DNA Replication and Central Carbon Metabolism in Escherichia coli
    Authors:
    Klaudyna Krause, Monika Maciag-Dorszynska, Anna Wosinski, Lidia Gaffke, Joanna Morcinek-Orłowska, Estera Rintz, Patrycja Bielanska, Agnieszka Szalewska-Pałasz, Georgi Muskhelishvili, Grzegorz Wegrzyn
    Academic press:
    Gene (rok: 2020, tom: 11(4), strony: 447), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/genes11040447 - link to the publication
  2. Multiple links connect central carbon metabolism to DNA replication initiation and elongation in Bacillus subtilis
    Authors:
    Hamid Nouri, Anne-Françoise Monnier, Solveig Fossum-Raunehaug, Monika Maciąg-Dorszyńska, Armelle Cabin-Flaman, François Képès, Grzegorz Węgrzyn, Agnieszka Szalewska-Pałasz, Vic Norris, Kirsten Skarstad, and Laurent Janniere
    Academic press:
    DNA Research (rok: 2018, tom: 25, strony: 641–653), Wydawca: Oxford Academic
    Status:
    Published
    DOI:
    10.1093/dnares/dsy031 - link to the publication
  3. The Absence of (p)ppGpp Renders Initiation of Escherichia coli Chromosomal DNA Synthesis Independent of Growth Rates
    Authors:
    Llorenç Fernández-Coll, Monika Maciag-Dorszynska, Krishma Tailor, Stephen Vadia, Petra Anne Levin, Agnieszka Szalewska-Palasz, and Michael Cashel
    Academic press:
    mbio (rok: 2020, tom: 11, strony: e03223-19), Wydawca: ASM
    Status:
    Published
    DOI:
    10.1128/mBio.03223-19 - link to the publication