Projects funded by the NCN
The Design, Synthesis and the Structural Analysis of Small-Molecule Probes for the Targeting of USP2 Deubiquitinase
2016/23/N/ST5/01588
Keywords:
USP2 Ub chemical probe NMR spectroscopy multicomponent reactions linear synthesis
Descriptors:
- NZ1_2: Biochemistry
- ST5_16:
Panel:
ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering
Host institution :
UNIWERSYTET JAGIELLOŃSKI, Wydzial Chemii UJ
woj. małopolskie
Principal investigator (from the host institution):
Number of co-investigators in the project: 2
Call: PRELUDIUM 12 - announced on 2016-09-15
Amount awarded: 50 000 PLN
Project start date (Y-m-d): 2017-10-05
Project end date (Y-m-d): 2018-10-04
Project duration:: 12 months (the same as in the proposal)
Project status: Project settled
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Publication in academic press/journals (1)
- Identification of Small-Molecule Inhibitors of USP2aAuthors:Marcin D. Tomala, Katarzyna Magiera-Mularz, Katarzyna Kubica , Sylwia Krzanik, Bartosz Zieba, Bogdan Musielak, Marcin Pustula, Grzegorz M. Popowicz, Michael Sattler, Grzegorz Dubin, Lukasz Skalniak, Tad A. HolakAcademic press:European Journal of Medicinal Chemistry (rok: 2018, tom: 150, strony: 261-267), Wydawca: ElsevierStatus:PublishedDOI:10.1016/j.ejmech.2018.03.009 - link to the publication