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Involvement of carbon monoxide (CO) in gastroprotection against experimental ischemia/reperfusion-induced gastric erosions

2016/23/N/NZ4/01890

Keywords:

carbon monoxide gastric ulcers gastroprotection ischemia/reperfusion

Descriptors:

  • NZ4_2: Physiology

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum, Wydział Lekarski

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Katarzyna Magierowska 

Number of co-investigators in the project: 2

Call: PRELUDIUM 12 - announced on 2016-09-15

Amount awarded: 49 800 PLN

Project start date (Y-m-d): 2017-08-09

Project end date (Y-m-d): 2019-08-08

Project duration:: 24 months (the same as in the proposal)

Project status: Project settled

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (3)
  1. Alterations in Gastric Mucosal Expression of Calcitonin Gene-Related Peptides, Vanilloid Receptors, and Heme Oxygenase-1 Mediate Gastroprotective Action of Carbon Monoxide against Ethanol-Induced Gastric Mucosal Lesions.
    Authors:
    Magierowska K, Wojcik D, Chmura A, Bakalarz D, Wierdak M, Kwiecien S, Sliwowski Z, Brzozowski T, Magierowski M.
    Academic press:
    Int J Mol Sci (rok: 2018, tom: 19 (10), strony: 45306), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms19102960 - link to the publication
  2. Emerging role of carbon monoxide in regulation of cellular pathways and in the maintenance of gastric mucosal integrity
    Authors:
    Magierowska K, Brzozowski T, Magierowski M
    Academic press:
    Pharmacological Research (rok: 2018, tom: 129, strony: 56-64), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.phrs.2018.01.008. - link to the publication
  3. Oxidative gastric mucosal damage induced by ischemia/reperfusion and the mechanisms of its prevention by carbon monoxide-releasing tricarbonyldichlororuthenium (II) dimer
    Authors:
    Katarzyna Magierowska, Edyta Korbut, Magdalena Hubalewska-Mazgaj, Marcin Surmiak, Anna Chmura, Dominik Bakalarz, Grzegorz Buszewicz, Dagmara Wójcik, Zbigniew Śliwowski, Grzegorz Ginter, Tomasz Gromowski, Sławomir Kwiecień, Tomasz Brzozowski, Marcin Magierowski
    Academic press:
    Free Radical Biology & Medicine (rok: 2019, tom: online, strony: S0891-5849(19)31177-3), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.freeradbiomed.2019.09.032 - link to the publication
  1. Carbon monoxide released from its pharmacological donor prevents gastric mucosa against oxidative ischemia/reperfusion-induced injury by the involvement of the atpdependent potassium channels and nitric oxide synthase activity
    Authors:
    Katarzyna Magierowska, Edyta Korbut, Dominik Bakalarz, Dagmara Wojcik, Zbigniew Sliwowski, Grzegorz Ginter, Anna Chmura, Slawomir Kwiecien, Marcin Magierowski, Tomasz Brzozowski
    Conference:
    Digestive Diseases Week 2019 (rok: 2019, ), Wydawca: American Gastroenterological Association
    Data:
    konferencja 18-21.05.2019
    Status:
    Published
  2. Role of gaseous mediator carbon monoxide in physiology and pathology of gastrointestinal tract
    Authors:
    Sliwowski Z, Magierowska K, Magierowski M, Kwiecien S, Hubalewska-Mazgaj M, Chmura A, Ginter G, Brzozowski T.
    Conference:
    27th Congress of the Polish Physiological Society (rok: 2017, ), Wydawca: Polish Pharmacological Society
    Data:
    konferencja 21-22 wrzesień 2017
    Status:
    Published
  3. ATP-dependent potassium channels, soluble guanylyl cyclase and endogenous prostaglandins in carbon monoxide-mediated prevention against oxidative ischemia/reperfusion-induced gastric damage
    Authors:
    Katarzyna Magierowska, Edyta Korbut, Dominik Bakalarz, Dagmara Wójcik, Magdalena Hubalewska-Mazgaj, Marcin Surmiak, Zbigniew Sliwowski, Grzegorz Buszewicz, Grzegorz Ginter, Anna Chmura, Slawomir Kwiecien, Tomasz Brzozowski, Marcin Magierowski
    Conference:
    United European Gastroenterology Week (rok: 2019, ), Wydawca: United European Gastroenterology Journal
    Data:
    konferencja 19-23.10.2019
    Status:
    Published

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