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Involvement of carbon monoxide (CO) in gastroprotection against experimental ischemia/reperfusion-induced gastric erosions

2016/23/N/NZ4/01890

Keywords

Descriptors

  • NZ4_2: Fizjologia

Panel

NZ4 – Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Lekarski

Voivodeship: małopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr Katarzyna Anna Magierowska

Number of co-investigators in the project: 2

Call

PRELUDIUM 12 – announced on 2016-09-15

Amount awarded
49 800 PLN
Project start date
2017-08-09
Project end date
2019-08-08
Project duration
24 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (3)

  1. Alterations in Gastric Mucosal Expression of Calcitonin Gene-Related Peptides, Vanilloid Receptors, and Heme Oxygenase-1 Mediate Gastroprotective Action of Carbon Monoxide against Ethanol-Induced Gastric Mucosal Lesions.

    Authors:
    Magierowska K, Wojcik D, Chmura A, Bakalarz D, Wierdak M, Kwiecien S, Sliwowski Z, Brzozowski T, Magierowski M.
    Academic press:
    Int J Mol Sci (year: 2018, volume: 19 (10), pages: 46037), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms19102960 – link to the publication

  2. Emerging role of carbon monoxide in regulation of cellular pathways and in the maintenance of gastric mucosal integrity

    Authors:
    Magierowska K, Brzozowski T, Magierowski M
    Academic press:
    Pharmacological Research (year: 2018, volume: 129, pages: 56-64), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.phrs.2018.01.008. – link to the publication

  3. Oxidative gastric mucosal damage induced by ischemia/reperfusion and the mechanisms of its prevention by carbon monoxide-releasing tricarbonyldichlororuthenium (II) dimer

    Authors:
    Katarzyna Magierowska, Edyta Korbut, Magdalena Hubalewska-Mazgaj, Marcin Surmiak, Anna Chmura, Dominik Bakalarz, Grzegorz Buszewicz, Dagmara Wójcik, Zbigniew Śliwowski, Grzegorz Ginter, Tomasz Gromowski, Sławomir Kwiecień, Tomasz Brzozowski, Marcin Magierowski
    Academic press:
    Free Radical Biology & Medicine (year: 2019, volume: online, pages: S0891-5849(19)31177-3), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.freeradbiomed.2019.09.032 – link to the publication

Articles in post-conference publications (3)

  1. ATP-dependent potassium channels, soluble guanylyl cyclase and endogenous prostaglandins in carbon monoxide-mediated prevention against oxidative ischemia/reperfusion-induced gastric damage

    Authors:
    Katarzyna Magierowska, Edyta Korbut, Dominik Bakalarz, Dagmara Wójcik, Magdalena Hubalewska-Mazgaj, Marcin Surmiak, Zbigniew Sliwowski, Grzegorz Buszewicz, Grzegorz Ginter, Anna Chmura, Slawomir Kwiecien, Tomasz Brzozowski, Marcin Magierowski
    Conference:
    United European Gastroenterology Week (year: 2019, pages: 964; P1925), Publisher: United European Gastroenterology Journal
    Date:
    conference 19-23.10.2019
    Status:
    Published

  2. Role of gaseous mediator carbon monoxide in physiology and pathology of gastrointestinal tract

    Authors:
    Sliwowski Z, Magierowska K, Magierowski M, Kwiecien S, Hubalewska-Mazgaj M, Chmura A, Ginter G, Brzozowski T.
    Conference:
    27th Congress of the Polish Physiological Society (year: 2017, pages: 81), Publisher: Polish Pharmacological Society
    Date:
    conference 21-22 wrzesień 2017
    Status:
    Published

  3. Carbon monoxide released from its pharmacological donor prevents gastric mucosa against oxidative ischemia/reperfusion-induced injury by the involvement of the atpdependent potassium channels and nitric oxide synthase activity

    Authors:
    Katarzyna Magierowska, Edyta Korbut, Dominik Bakalarz, Dagmara Wojcik, Zbigniew Sliwowski, Grzegorz Ginter, Anna Chmura, Slawomir Kwiecien, Marcin Magierowski, Tomasz Brzozowski
    Conference:
    Digestive Diseases Week 2019 (year: 2019, pages: S503), Publisher: American Gastroenterological Association
    Date:
    conference 18-21.05.2019
    Status:
    Published

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