Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Evaluation of photoinactivation potential in the eradication of Streptococcus agalactiae carrier-state in the urogenital system: in vitro and in vivo studies

2016/23/B/NZ7/03236

Keywords:

cytotoxicity GBS carrier state mutagenicity photoinactivation Streptococcus agalactiae

Descriptors:

  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

woj. pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Mariusz Grinholc 

Number of co-investigators in the project: 4

Call: OPUS 12 - announced on 2016-09-15

Amount awarded: 671 600 PLN

Project start date (Y-m-d): 2017-10-02

Project end date (Y-m-d): 2021-10-01

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Inkubator CO2 (25 000 PLN)
  2. System do hodowli biofilmu w warunkach stałego przepływu (2 szt.) (20 000 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  • Articles in post-conference publications (1)
  1. Optimization of Streptococcus agalactiae Biofilm Culture in a Continuous Flow System for Photoinactivation Studies
    Authors:
    Michal K. Pieranski, Michal Rychlowsk, Mariusz Grinholc
    Academic press:
    Pathogens (rok: 2021, tom: 10, strony: 1212), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/pathogens10091 - link to the publication
  2. Increased photoinactivation stress tolerance of Streptococcus agalactiae upon consecutive sublethal phototreatments
    Authors:
    Michał Pierański, Izabela Sitkiewicz, Mariusz Grinholc
    Academic press:
    Free Radical Biology and Medicine (rok: 2020, tom: 160, strony: 657-669), Wydawca: Elsevier Scientific Inc
    Status:
    Published
    DOI:
    10.1016/j.freeradbiomed.2020.09.003 - link to the publication
  3. An extended Logistic model of photodynamic inactivation for various levels of irradiation intensity using the example of Streptococcus agalactiae
    Authors:
    M. Brasel, M. Pieranski, M. Grinholc
    Academic press:
    Scientific Reports (rok: 2020, tom: 10, strony: 14168), Wydawca: Nature Publishing Group
    Status:
    Published
    DOI:
    10.1038/s41598-020-71033-7 - link to the publication
  4. Antimicrobial Blue Light Photoinactivation of Pseudomonas aeruginosa: Quorum Sensing Signaling Molecules, Biofilm Formation and Pathogenicity.
    Authors:
    Fila G., Krychowiak M., Rychlowski M., Bielawski K.P., Grinholc M.
    Academic press:
    Journal of Biophotonics (rok: 2018, tom: 11, strony: 45303), Wydawca: WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
    Status:
    Published
    DOI:
    10.1002/jbio.201800079 - link to the publication
  1. MODELLING OF DYNAMIC PROPERTIES OF PHOTOINACTIVATION PROCESS
    Authors:
    M.K. Pieranski, M. Brasel, M. Grinholc
    Conference:
    Light&Life 18th Congress of the European Society for Photobiology (rok: 2019, ), Wydawca: MCI Spain Event Services
    Data:
    konferencja 25-30.08
    Status:
    Published

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