The measurement of oxidative stress status by fluorescence detection of spin-trapped adducts with reactive nitrogen and oxygen species

2016/23/D/ST4/01576

Keywords

Descriptors

  • ST4_3: Metody spektroskopowe i spektrometryczne
  • ST4_6: Chemia analityczna

Panel

ST4 – Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution

Uniwersytet Gdański, Wydział Chemii

Voivodeship: pomorskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr Krzysztof Michał Żamojć

Number of co-investigators in the project: 3

Call

SONATA 12 – announced on 2016-09-15

Amount awarded
633 085 PLN
Project start date
2017-07-13
Project end date
2022-07-12
Project duration
60 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Wysokosprawny chromatograf cieczowy (HPLC) z detektorem UV-DAD i fluorescencyjnym (np. Dionex Ultimate 3000 LC System). Cost: 251 600 PLN

Information in the final report

Publication in academic press/journals (12)

  1. Key role of histidine residues orientation in affinity binding of model pentapeptides with Ni2+ ions: A theoretical supported experimental study

    Authors:
    Krzysztof Żamojć, Dariusz Wyrzykowski, Giuseppina Sabatino, Anna Maria Papini, Robert Wieczorek, Lech Chmurzyński, Joanna Makowska
    Academic press:
    Journal of Molecular Liquids (year: 2021, volume: 341, pages: 117414), Publisher: ELSEVIER, RADARWEG 29, 1043 NX AMSTERDAM, NETHERLANDS
    Status:
    Published
    DOI:
    10.1016/j.molliq.2021.117414 – link to the publication
  2. Physicochemical nature of sodium dodecyl sulfate interactions with bovine serum albumin revealed by interdisciplinary approaches

    Authors:
    Aleksandra Tesmar, Małgorzata M. Kogut, Krzysztof Żamojć, Ola Grabowska, Katarzyna Chmur, Sergey A. Samsonov, Joanna Makowska, Dariusz Wyrzykowski, Lech Chmurzyński
    Academic press:
    Journal of Molecular Liquids (year: 2021, volume: 340, pages: 117185), Publisher: ELSEVIER, RADARWEG 29, 1043 NX AMSTERDAM, NETHERLANDS
    Status:
    Published
    DOI:
    10.1016/j.molliq.2021.117185 – link to the publication
  3. Fluorescence quenching studies on the interactions between chosen fluoroquinolones and selected stable TEMPO and PROXYL nitroxides

    Authors:
    Krzysztof Żamojć, Irena Bylińska, Wiesław Wiczk, Lech Chmurzyński
    Academic press:
    International Journal of Molecular Sciences (year: 2021, volume: 22, pages: Article number: 885), Publisher: MDPI, ST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND
    Status:
    Published
    DOI:
    10.3390/ijms22020885 – link to the publication
  4. Effect of tetraphenylborate on physicochemical properties of bovine serum albumin

    Authors:
    Ola Grabowska, Małgorzata M. Kogut, Krzysztof Żamojć, Sergey A. Samsonov, Joanna Makowska, Aleksandra Tesmar, Katarzyna Chmur, Dariusz Wyrzykowski, Lech Chmurzyński
    Academic press:
    Molecules (year: 2021, volume: 26, pages: 6565), Publisher: MDPI, ST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND
    Status:
    Published
  5. On the effect of pH, temperature, and surfactant structure on bovine serum albumin–cationic/anionic/nonionic surfactants interactions in cacodylate buffer – fluorescence quenching studies supported by UV spectrophotometry and CD spectroscopy

    Authors:
    Krzysztof Żamojć, Dariusz Wyrzykowski, Lech Chmurzyński
    Academic press:
    International Journal of Molecular Sciences (year: 2022, volume: 23, pages: 41), Publisher: MDPI, ST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND
    Status:
    Published
    DOI:
    10.3390/ijms23010041 – link to the publication
  6. Interactions of Aβ1-42 peptide and its three fragments (Aβ8-12, Aβ8-13, and Aβ5-16) with selected nonsteroidal drugs and compounds of natural origin

    Authors:
    Krzysztof Żamojć, Karolina Streńska, Dariusz Wyrzykowski, Lech Chmurzyński, Joanna Makowska
    Academic press:
    Symmetry (year: 2020, volume: 12, pages: Article number: 1579), Publisher: MDPI, ST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND
    Status:
    Published
    DOI:
    10.3390/sym12101579 – link to the publication
  7. Copper(II) complexation by fragment of central part of FBP28 protein from Mus musculus

    Authors:
    Joanna Makowska, Krzysztof Żamojć, Dariusz Wyrzykowski, Wiesław Wiczk, Lech Chmurzyński
    Academic press:
    Biophysical Chemistry (year: 2018, volume: 241, pages: 55-60), Publisher: ELSEVIER SCIENCE BV, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
    Status:
    Published
    DOI:
    10.1016/j.bpc.2018.08.002 – link to the publication
  8. The influence of the type of substituents and the solvent on the interactions between different coumarins and selected TEMPO analogues – Fluorescence quenching studies

    Authors:
    Krzysztof Żamojć, Wiesław Wiczk, Lech Chmurzyński
    Academic press:
    Chemical Physics (year: 2018, volume: 513, pages: 188-194), Publisher: ELSEVIER SCIENCE BV, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
    Status:
    Published
    DOI:
    10.1016/j.chemphys.2018.08.005 – link to the publication
  9. On the use of acridinium indicators for the chemiluminecent determination of the total antioxidant capacity of dietary supplements

    Authors:
    Karol Krzymiński, Alexander Roshal, Paweł Rudnicki-Velasquez, Krzysztof Żamojć
    Academic press:
    Luminescence (year: 2019, volume: 34, pages: 512-519), Publisher: WILEY, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
    Status:
    Published
    DOI:
    10.1002/bio.3629 – link to the publication
  10. Tautomerism of N-substituted acridin-9-amines in the context of dynamic NMR and matrix isolation-FT-IR spectroscopy supported by DFT calculations and structural analysis

    Authors:
    Karol Krzymiński, Beata Zadykowicz, Piotr Storoniak, Michał Wera, Krzysztof Żamojć
    Academic press:
    Journal of Molecular Structure (year: 2020, volume: 1218, pages: Article number: 128424), Publisher: ELSEVIER, RADARWEG 29, 1043 NX AMSTERDAM, NETHERLANDS
    Status:
    Published
    DOI:
    10.1016/j.molstruc.2020.128424 – link to the publication
  11. A pentapeptide with tyrosine moiety as fluorescent chemosensor for selective nanomolar-level detection of copper(II) ions

    Authors:
    Krzysztof Żamojć, Dominik Kamrowski, Magdalena Zdrowowicz, Dariusz Wyrzykowski, Wiesław Wiczk, Lech Chmurzyński, Joanna Makowska
    Academic press:
    International Journal of Molecular Sciences (year: 2020, volume: 20, pages: Article number: 743), Publisher: MDPI, ST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND
    Status:
    Published
    DOI:
    10.3390/ijms21030743 – link to the publication
  12. Dihydroxy-substituted coumarins as fluorescent probes for nanomolar-level detectionk of the 4-amino-TEMPO spin label

    Authors:
    Krzysztof Żamojć, Magdalena Zdrowowicz, Aleksandra Hać, Maciej Witwicki, Paweł Rudnicki-Velasquez, Dariusz Wyrzykowski, Wiesław Wiczk, Lech Chmurzyński
    Academic press:
    International Journal of Molecular Sciences (year: 2019, volume: 20, pages: Article number: 3802), Publisher: MDPI, ST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND
    Status:
    Published
    DOI:
    10.3390/ijms20153802 – link to the publication

Articles in post-conference publications (3)

  1. Wykorzystanie pułapek spinowych w oznaczaniu wolnych rodników

    Authors:
    Krzysztof Żamojć, Joanna Makowska, Dariusz Wyrzykowski, Lech Chmurzyński
    Conference:
    XI Ogólnopolskie Sympozjum Nauka i przemysł - metody spektroskopowe w praktyce, nowe wyzwania i możliwości (year: 2019, pages: 110-113), Publisher: Wydawnictwo Uniwersytetu Marii Curie-Skłodowskiej, Lublin
    Date:
    conference 25-27 czerwca 2019 r.
    Status:
    Published
  2. Badania aktywności przeciwutleniającej związków kompleksowych oksowanadu(IV)

    Authors:
    Aleksandra Tesmar, Dariusz Wyrzykowski, Krzysztof Żamojć, Joanna Makowska, Lech Chmurzyński
    Conference:
    XI Ogólnopolskie Sympozjum Nauka i przemysł - metody spektroskopowe w praktyce, nowe wyzwania i możliwości (year: 2019, pages: 118-121), Publisher: Wydawnictwo Uniwersytetu Marii Curie-Skłodowskiej, Lublin
    Date:
    conference 25-27 czerwca 2019 r.
    Status:
    Published
  3. Wykorzystanie metody kalorymetrycznej oraz spektroskopii fluorescencyjnej do badania oddziaływań fragmentu białka AB(1-42) z jonami miedzi(II)

    Authors:
    Joanna Makowska, Krzysztof Żamojć, Dariusz Wyrzykowski, Wiesław Wiczk, Lech Chmurzyński
    Conference:
    XI Ogólnopolskie Sympozjum Nauka i przemysł - metody spektroskopowe w praktyce, nowe wyzwania i możliwości (year: 2019, pages: 114-117), Publisher: Wydawnictwo Uniwersytetu Marii Curie-Skłodowskiej, Lublin
    Date:
    conference 25-27 czerwca 2019 r.
    Status:
    Published

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Graphic design and implementation: Jakub Piotrowski