Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Mechanism of incorporation of lipid liquid crystalline drug carriers - cubosomes and and hexosomes into lipid membranes

2016/23/B/ST4/03295

Keywords:

Langmuir-Blodgett monolayer cubosome liquid crystalline phase surface pressure voltammetry

Descriptors:

  • ST4_5: Analytical chemistry

Panel:

ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution :

Uniwersytet Warszawski, Wydział Chemii

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Renata Bilewicz 

Number of co-investigators in the project: 5

Call: OPUS 12 - announced on 2016-09-15

Amount awarded: 924 420 PLN

Project start date (Y-m-d): 2017-07-17

Project end date (Y-m-d): 2021-06-16

Project duration:: 47 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. interfejs.
  2. Układ Wanna Langmuira-Blodgett z mikrowanienką (140 000 PLN)

Information in the final report

  • Publication in academic press/journals (8)
  1. PM-IRRAS Study on the Effect of Phytantriol-Based Cubosomes on DMPC Bilayers as Model Lipid Membranes
    Authors:
    Julia Alvarez-Malmagro, Dorota Matyszewska, Ewa Nazaruk, Piotr Szwedziak and Renata Bilewicz
    Academic press:
    Langmuir (rok: 2019, tom: 35, strony: 16650−16660), Wydawca: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acs.langmuir.9b02974 - link to the publication
  2. Electrogenic transport of Na+/K+ -ATPase incorporated in lipidic cubic phases as a model biomimetic membrane
    Authors:
    Martina Zatloukalova, Ewa Nazaruk, Renata Bilewicz
    Academic press:
    Electrochimica Acta (rok: 2019, tom: 310, strony: 113-121), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.electacta.2019.04.082 - link to the publication
  3. Impact of pH and cell medium on the interaction of doxorubicin with lipoic acid cyclodextrin conjugate as the drug carrier
    Authors:
    Olga Swiech, Maciej Majdecki, Lidia J. Opuchlik, Renata Bilewicz
    Academic press:
    Journal of Inclusion Phenomena and Macrocyclic Chemistry (rok: 2020, tom: 97, strony: 129–136), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s10847-020-00994-z - link to the publication
  4. Lipidic Liquid Crystalline Cubic Phases and Magnetocubosomes as Methotrexate Carriers
    Authors:
    Monika Mierzwa, Adrianna Cytryniak, Paweł Krysiński and Renata Bilewicz
    Academic press:
    Nanomaterials (rok: 2019, tom: 9, strony: 636-652), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/nano9040636 - link to the publication
  5. Voltammetric and biological studies of folate-targeted non-lamellar lipid mesophases
    Authors:
    Marlena Godlewska, Agnieszka Majkowska-Pilip, Anna Stachurska, Jan F. Biernat, Damian Gaweł, Ewa Nazaruk
    Academic press:
    Electrochimica Acta (rok: 2019, tom: 299, strony: 45302), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.electacta.2018.12.164 - link to the publication
  6. Voltammetric/UV–Vis study of temozolomide inclusion complexes with cyclodextrin derivatives
    Authors:
    Agata Krzak, Renata Bilewicz
    Academic press:
    Bioelectrochemistry (rok: 2020, tom: 136, strony: 107587), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bioelechem.2020.107587 - link to the publication
  7. How do lipid nanocarriers – Cubosomes affect electrochemical properties of DMPC bilayers deposited on gold (111) electrodes?
    Authors:
    Julia Alvarez-Malmagro, Elżbieta Jabłonowska, Ewa Nazaruk, Piotr Szwedziak, Renata Bilewicz
    Academic press:
    Bioelectrochemistry (rok: 2020, tom: 134, strony: 107516), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bioelechem.2020.107516 - link to the publication
  8. Lipid membranes exposed to dispersions of phytantriol and monoolein cubosomes: Langmuir monolayer and HeLa cell membrane studies
    Authors:
    Elżbieta Jabłonowska, Dorota Matyszewska, Ewa Nazaruk, Marlena Godlewska, Damian Gaweł, Renata Bilewicz
    Academic press:
    Biochimica et Biophysica Acta (BBA) - General Subjects (rok: 2021, tom: 1865, strony: 129738), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbagen.2020.129738 - link to the publication

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