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Scaling up of protein chromatography

2016/22/M/ST8/00193

Keywords

Descriptors

  • ST8_1: Inżynieria chemiczna, chemia techniczna, inżynieria środowiska, inżynieria sanitarna, inżynieria procesowa

Panel

ST8 – Production and processes engineering: modelling, product design, process design and control, construction methods and engineering, power units and systems

Host institution

Politechnika Rzeszowska im. Ignacego Łukasiewicza, Wydział Chemiczny

Voivodeship: podkarpackie

Other projects carried out by the institution »

Principal investigator (from the host institution)

prof. Dorota Antos

Number of co-investigators in the project: 7

Call

HARMONIA 8 – announced on 2016-06-15

Amount awarded
531 700 PLN
Project start date
2017-04-10
Project end date
2020-04-09
Project duration
36 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. w grancie HARMONIA nie wolno kupować aparatury - nie zakupiono.

Information in the final report

Publication in academic press/journals (3)

  1. Prediction tool for loading, isocratic elution, gradient elution and scaling up of ion exchange chromatography of proteins

    Authors:
    Marek W., Sauer D., Dürauer A., Jungbauer A., Piatkowski W., Antos D.
    Academic press:
    J. Chromatogr. A (year: 2018, volume: 1566, pages: 89–101), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.chroma.2018.06.057. – link to the publication

  2. Effect of flow behavior in extra-column volumes on the retention pattern of proteins in a small column

    Authors:
    Baran K., Marek W.K., Piątkowski W., Antos D.
    Academic press:
    J. Chromatogr. A (year: 2019, volume: 1598, pages: 154–162), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.chroma.2019.03.060 – link to the publication

  3. Scale up of a chromatographic capture step for a clarified bacterial homogenate – influence of mass transport limitationand competitive adsorption of impurities,

    Authors:
    Kołodziej M., Sauer D.G., Beck J., Marek W K., Hahn R., Jungbauer A.,, Dürauer A., Piątkowski W., Antos D.
    Academic press:
    J. Chromatogr. A (year: 2020, volume: 1618, 460856;, pages: 46033), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.chroma.2020.460856 – link to the publication

Articles in post-conference publications (9)

  1. Scale up of a chromatographic capture step for a clarified bacterial homogenate – influence of feed viscosity and competitive adsorption of impurities

    Authors:
    Kołodziej M., Sauer D.G., Beck J., Marek W.K., Hahn R., Jungbauer A, Dürauer A., Piątkowski W., Antos D.
    Conference:
    PREP 2019, Baltimore, USA (year: 2019, pages: P-M-114), Publisher: Organizing Committee
    Date:
    conference 2019-07-7-10
    Status:
    Published

  2. Mathematical Tool for Design and Scaling up Protein Chromatography

    Authors:
    Marek W.K., Piątkowski W., Antos D.
    Conference:
    23 Polish Conference on Chemical & Process Engineering, Jachranka (year: 2019, pages: 100; Book of Abstracts L 04-21), Publisher: Polish Academy of Science – Committee of Chemical & Process Engineering
    Date:
    conference 2019-06-2-5
    Status:
    Published

  3. Scalability of mini-columns in protein chromatograph

    Authors:
    Wojciech Marek, Jakub Gac, Krystian Baran, Wojciech Piątkowski, Dorota Antos
    Conference:
    SPICA 2018 (year: 2018, pages: Lecture - OC17), Publisher: The Scientific Committee
    Date:
    conference October 7-10, 2018, Darmstadt, Germany.
    Status:
    Published

  4. Pitfalls in Design and Scaling up Protein Chromatography

    Authors:
    Michał Kołodziej, Izabela Poplewska, Wojciech Piątkowski, Dorota Antos
    Conference:
    PEGS Europe (year: 2018, pages: Kyenote Lecture - 5C-14:35), Publisher: CHI, 250 First Avenue, Suite 300 Needham, MA 02494, USA
    Date:
    conference November 15-16, Lisboa, Portugal
    Status:
    Published

  5. Effect of flow behavior in extra-column volumes on the retention pattern of proteins in small columns

    Authors:
    Baran K., Marek W.K., Poplewska I., Piątkowski W., Antos
    Conference:
    ECCE12/ECAB5, 2019, Florence, Italy (year: 2019, pages: P 403), Publisher: Organizing Committee
    Date:
    conference 2019-09-15-19
    Status:
    Published

  6. Predicting Tool for Design and Scaling up Protein Chromatography

    Authors:
    Wojciech Kazimierz Mareka, Dominik Sauer, Astrid Dürauer, Alois Jungbauer, Wojciech Piątkowskia, Dorota Antos
    Conference:
    PEGS Europe (year: 2018, pages: Poster-C-49), Publisher: CHI, 250 First Avenue, Suite 300 Needham, MA 02494, USA
    Date:
    conference November 15-16, Lisboa, Portugal
    Status:
    Published

  7. Pitfalls to avoid when modelling and scale up of protein chromatography

    Authors:
    Jakub Gac, Wojciech Marek, Wojciech Piątkowski, Dorota Antos
    Conference:
    PREP2018 (year: 2018, pages: Lecture 212), Publisher: Organizing Committee
    Date:
    conference July 8-11, Baltimore, USA
    Status:
    Published

  8. Effect of extra-column volumes on the efficiency of protein chromatography

    Authors:
    Baran K., Marek W.K., Piątkowski W., Antos D.
    Conference:
    23 Polish Conference on Chemical & Process Engineering, Jachranka (year: 2019, pages: 6 - Book of Abstracts P-2-02), Publisher: Polish Academy of Science – Committee of Chemical & Process Engineering
    Date:
    conference 2019-06-2-5
    Status:
    Published

  9. Moment Analysis Technique for Scaling-up Protein Chromatography

    Authors:
    Wojciech Marek, Astrid Dürauer,Alois Jungbauer, Wojciech Piątkowski, Dorota Antos
    Conference:
    PREP 2017 (year: 2017, pages: L-211), Publisher: Organizing Committee
    Date:
    conference 16-18.06.2017, Philadelphia, USA
    Status:
    Published

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