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Information of the project and the call

Keywords

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Scaling up of protein chromatography

2016/22/M/ST8/00193

Keywords:

recombinant proteins chromatography scaling up mathematical modeling

Descriptors:

  • ST8_1: Chemical engineering, technical chemistry, environmental engineering, sanitary engineering, engineering of chemical processes

Panel:

ST8 - Production and processes engineering: modelling, product design, process design and control, construction methods and engineering, power units and systems

Host institution :

Politechnika Rzeszowska im. Ignacego Łukasiewicza, Wydział Chemiczny

woj. podkarpackie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Dorota Antos 

Number of co-investigators in the project: 7

Call: HARMONIA 8 - announced on 2016-06-15

Amount awarded: 531 700 PLN

Project start date (Y-m-d): 2017-04-10

Project end date (Y-m-d): 2020-04-09

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. w grancie HARMONIA nie wolno kupować aparatury - nie zakupiono.

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (9)
  1. Effect of flow behavior in extra-column volumes on the retention pattern of proteins in a small column
    Authors:
    Baran K., Marek W.K., Piątkowski W., Antos D.
    Academic press:
    J. Chromatogr. A (rok: 2019, tom: 1598, strony: 154–162), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.chroma.2019.03.060 - link to the publication
  2. Scale up of a chromatographic capture step for a clarified bacterial homogenate – influence of mass transport limitationand competitive adsorption of impurities",
    Authors:
    Kołodziej M., Sauer D.G., Beck J., Marek W K., Hahn R., Jungbauer A.,, Dürauer A., Piątkowski W., Antos D.
    Academic press:
    J. Chromatogr. A (rok: 2020, tom: 1618, 460856;, strony: 45302), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.chroma.2020.460856 - link to the publication
  3. Prediction tool for loading, isocratic elution, gradient elution and scaling up of ion exchange chromatography of proteins"
    Authors:
    Marek W., Sauer D., Dürauer A., Jungbauer A., Piatkowski W., Antos D.
    Academic press:
    J. Chromatogr. A (rok: 2018, tom: 1566, strony: 89–101), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.chroma.2018.06.057. - link to the publication
  1. Effect of flow behavior in extra-column volumes on the retention pattern of proteins in small columns
    Authors:
    Baran K., Marek W.K., Poplewska I., Piątkowski W., Antos
    Conference:
    ECCE12/ECAB5, 2019, Florence, Italy (rok: 2019, ), Wydawca: Organizing Committee
    Data:
    konferencja 2019-09-15-19
    Status:
    Published
  2. Effect of extra-column volumes on the efficiency of protein chromatography
    Authors:
    Baran K., Marek W.K., Piątkowski W., Antos D.
    Conference:
    23 Polish Conference on Chemical & Process Engineering, Jachranka (rok: 2019, ), Wydawca: Polish Academy of Science – Committee of Chemical & Process Engineering
    Data:
    konferencja 2019-06-2-5
    Status:
    Published
  3. Predicting Tool for Design and Scaling up Protein Chromatography
    Authors:
    Wojciech Kazimierz Mareka, Dominik Sauer, Astrid Dürauer, Alois Jungbauer, Wojciech Piątkowskia, Dorota Antos
    Conference:
    PEGS Europe (rok: 2018, ), Wydawca: CHI, 250 First Avenue, Suite 300 Needham, MA 02494, USA
    Data:
    konferencja November 15-16, Lisboa, Portugal
    Status:
    Published
  4. Scalability of mini-columns in protein chromatograph
    Authors:
    Wojciech Marek, Jakub Gac, Krystian Baran, Wojciech Piątkowski, Dorota Antos
    Conference:
    SPICA 2018 (rok: 2018, ), Wydawca: The Scientific Committee
    Data:
    konferencja October 7-10, 2018, Darmstadt, Germany.
    Status:
    Published
  5. Mathematical Tool for Design and Scaling up Protein Chromatography
    Authors:
    Marek W.K., Piątkowski W., Antos D.
    Conference:
    23 Polish Conference on Chemical & Process Engineering, Jachranka (rok: 2019, ), Wydawca: Polish Academy of Science – Committee of Chemical & Process Engineering
    Data:
    konferencja 2019-06-2-5
    Status:
    Published
  6. Pitfalls to avoid when modelling and scale up of protein chromatography
    Authors:
    Jakub Gac, Wojciech Marek, Wojciech Piątkowski, Dorota Antos
    Conference:
    PREP2018 (rok: 2018, ), Wydawca: Organizing Committee
    Data:
    konferencja July 8-11, Baltimore, USA
    Status:
    Published
  7. Moment Analysis Technique for Scaling-up Protein Chromatography
    Authors:
    Wojciech Marek, Astrid Dürauer,Alois Jungbauer, Wojciech Piątkowski, Dorota Antos
    Conference:
    PREP 2017 (rok: 2017, ), Wydawca: Organizing Committee
    Data:
    konferencja 16-18.06.2017, Philadelphia, USA
    Status:
    Published
  8. Pitfalls in Design and Scaling up Protein Chromatography
    Authors:
    Michał Kołodziej, Izabela Poplewska, Wojciech Piątkowski, Dorota Antos
    Conference:
    PEGS Europe (rok: 2018, ), Wydawca: CHI, 250 First Avenue, Suite 300 Needham, MA 02494, USA
    Data:
    konferencja November 15-16, Lisboa, Portugal
    Status:
    Published
  9. Scale up of a chromatographic capture step for a clarified bacterial homogenate – influence of feed viscosity and competitive adsorption of impurities
    Authors:
    Kołodziej M., Sauer D.G., Beck J., Marek W.K., Hahn R., Jungbauer A, Dürauer A., Piątkowski W., Antos D.
    Conference:
    PREP 2019, Baltimore, USA (rok: 2019, ), Wydawca: Organizing Committee
    Data:
    konferencja 2019-07-7-10
    Status:
    Published

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