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The development of spectroscopic analysis of lipid droplets in vitro: biochemistry, and their localisation in relation to the biological function

2016/22/M/ST4/00150

Keywords:

Raman FT-IR imaging chemometrics

Descriptors:

  • ST4_3: Molecular architecture and structure
  • ST4_13: Solid-state chemistry, surface physicochemistry

Panel:

ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution :

Uniwersytet Jagielloński, Wydział Chemii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Małgorzata Barańska 

Number of co-investigators in the project: 10

Call: HARMONIA 8 - announced on 2016-06-15

Amount awarded: 949 000 PLN

Project start date (Y-m-d): 2017-04-11

Project end date (Y-m-d): 2022-04-10

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (12)
  1. Diversity among endothelial cell lines revealed by Raman and Fourier-transform infrared spectroscopic imaging
    Authors:
    Ewelina Szafraniec, Ewelina Wiercigroch, Krzysztof Czamara, Katarzyna Majzner, Emilia Staniszewska-Slezak, Katarzyna M. Marzec, Kamilla Malek, Agnieszka Kaczor, Malgorzata Baranska
    Academic press:
    Analyst (rok: 2018, tom: 143, strony: 4323-4334), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/c8an00239h - link to the publication
  2. FT-IR Spectroscopic Imaging of Endothelial Cells Response to Tumor Necrosis Factor-α: To Follow Markers of Inflammation Using Standard and High-Magnification Resolution
    Authors:
    Ewelina Wiercigroch, Emilia Staniszewska-Slezak, Kinga Szkaradek, Tomasz Wojcik, Yukihiro Ozaki, Malgorzata Baranska, Kamilla Malek
    Academic press:
    Analytical Chemistry (rok: 2018, tom: 90, strony: 3727-3736), Wydawca: ACS Publications
    Status:
    Published
    DOI:
    10.1021/acs.analchem.7b03089 - link to the publication
  3. Lipid Droplet Composition Varies Based on Medaka Fish Eggs Development as Revealed by NIR-, MIR-, and Raman Imaging
    Authors:
    E. Bik, M. Ishigaki, A. Blat, A. Jasztal, Y. Ozaki, K. Malek , M. Baranska
    Academic press:
    Molecules (rok: 2020, tom: 25, strony: 45306), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/molecules25040817 - link to the publication
  4. Lipid droplets in mammalian eggs are utilized during embryonic diapause
    Authors:
    Roberta Arena, Simona Bisogno, Łukasz Gąsior, Joanna Rudnicka, Laura Bernhardt, Thomas Haaf, Federica Zacchini, Michał Bochenek, Kinga Fic, Ewelina Bik, Małgorzata Barańska, Anna Bodzoń-Kułakowska, Piotr Suder, Joanna Depciuch,Artur Gurgul, Zbigniew Polański, and Grażyna E. Ptak
    Academic press:
    Proceedings of the National Academy of Sciences of the United States of America (rok: 2021, tom: 118, strony: 45300), Wydawca: National Academy of Sciences
    Status:
    Published
    DOI:
    10.1073/pnas.2018362118 - link to the publication
  5. Eosinophils and Neutrophils—Molecular Differences Revealed by Spontaneous Raman, CARS and Fluorescence Microscopy
    Authors:
    Aleksandra Dorosz, Marek Grosicki, Jakub Dybas, Ewelina Matuszyk, Marko Rodewald, Tobias Meyer, Jürgen Popp, Kamilla Malek, Malgorzata Baranska
    Academic press:
    Cells (rok: 2020, tom: 9, strony: 45306), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cells9092041 - link to the publication
  6. Identification of inflammatory markers in eosinophilic cells of the immune system: fluorescence, Raman and CARS imaging can recognize markers but differently
    Authors:
    Aleksandra Borek-Dorosz, Marek Grosicki, Jakub Dybas, Ewelina Matuszyk, Marko Rodewald, Tobias Meyer-Zedler, Michael Schmitt, Juergen Popp, Kamilla Malek, Malgorzata Baranska
    Academic press:
    Cellular and Molecular Life Sciences (rok: 2022, tom: 79, strony: 45303), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s00018-021-04058-4 - link to the publication
  7. Tunicamycin induced endoplasmic reticulum changes in endothelial cells investigated in vitro by confocal Raman imaging
    Authors:
    E. Bik, N. Mielniczek, M. Jarosz, J. Denbigh, R. Budzynska, M. Baranska, K. Majzner
    Academic press:
    Analyst (rok: 2019, tom: 144, strony: 6561–6569), Wydawca: The Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/c9an01456j - link to the publication
  8. Differential response of liver sinusoidal endothelial cells and hepatocytes to oleic and palmitic acid revealed by Raman and CARS imaging
    Authors:
    E. Matuszyk, E. Sierka, M. Rodewald, H. Bae, T. Meyer, E. Kus, S. Chlopicki, M. Schmitt,J. Popp, M. Barańska
    Academic press:
    BBA - Molecular Basis of Disease (rok: 2020, tom: 1866, strony: 165763–165772), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbadis.2020.165763 - link to the publication
  9. Raman imaging highlights biochemical heterogeneity ofhuman eosinophils versus human eosinophilic leukemia cellline
    Authors:
    A. Rygula, R. Ferreira Fernandes, M. Grosicki, B. Kukla, P. Leszczenko, D. Augustynska, A. Cernescu, A. Dorosz, K. Malek, M, Baranska
    Academic press:
    British Journal of Haematology (rok: 2019, tom: 186, strony: 685 - 694), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1111/bjh.15971 - link to the publication
  10. Comparison of standard and HD FT-IR with multimodal CARS/TPEF/SHG/FLIMS imaging in the detection of the early stage of pulmonary metastasis of murine breast cancer
    Authors:
    Karolina Chrabaszcz, Tobias Meyer, Hyeonsoo Bae, Michael Schmitt, Agnieszka Jasztal, Marta Smeda, Marta Stojak, Jürgen Popp, Kamilla Malek, Katarzyna M. Marzec
    Academic press:
    Analyst (rok: 2020, tom: 145, strony: 4982-4990), Wydawca: The Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/d0an00762e - link to the publication
  11. Raman spectroscopy – based insight into lipid droplets presence and contents in liver sinusoidal endothelial cells and hepatocytes
    Authors:
    E.Szafraniec, E.Kus, A.Wislocka, B.Kukla, E.Sierka, V.Untereiner, G.Sockalingum, S.Chlopicki, M. Baranska
    Academic press:
    Journal of Biophotonics (rok: 2019, tom: 14, strony: 45302), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1002/jbio.201800290 - link to the publication
  12. Label-free in vivo Raman microspectroscopic imaging of the macromolecular architecture of oocytes
    Authors:
    Philip Heraud, Katarzyna Maria Marzec, Qing‒Hua Zhang, Wai Shan Yuen, John Carroll, Bayden R. Wood
    Academic press:
    Scientific Reports (rok: 2017, tom: 7, strony: 45301), Wydawca: Nature
    Status:
    Published
    DOI:
    10.1038/s41598-017-08973-0 - link to the publication

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