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Detailed mechanism of resting state membrane raft formation via dissecting the MPP1-flotillins/lipids interactions in vitro

2016/21/B/NZ1/02821

Keywords

Descriptors

  • NZ1_2: Biochemia
  • NZ1_11: Inne zagadnienia pokrewne
  • NZ3_1: Biologia komórki

Panel

NZ1 – Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution

Uniwersytet Wrocławski, Wydział Biotechnologii

Voivodeship: dolnośląskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr hab. Aleksander Ryszard Czogalla

Number of co-investigators in the project: 5

Call

OPUS 11 – announced on 2016-03-15

Amount awarded
960 480 PLN
Project start date
2017-01-12
Project end date
2021-01-11
Project duration
48 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Komora CO2 z wytrząsaniem i nawilżaniem atmosfery. Cost: 90 000 PLN
  2. Osmometr Marcel OS3000.

Information in the final report

Publication in academic press/journals (5)

  1. MPP1 Determines the Mobility of Flotillins and Controls the Confinement of Raft-Associated Molecules

    Authors:
    Agnieszka Biernatowska, Karolina Wójtowicz, Tomasz Trombik, Aleksander F. Sikorski, Aleksander Czogalla
    Academic press:
    Cells (year: 2022, volume: 11, pages: 311), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/cells11030311 – link to the publication

  2. Molecular characterization of direct interactions between MPP1 and flotillins

    Authors:
    Agnieszka Biernatowska, Paulina Olszewska, Krzysztof Grzymajło, Dominik Drabik, Sebastian Kraszewski, Aleksander F. Sikorski, Aleksander Czogalla
    Academic press:
    Scientific Reports (year: 2021, volume: 11, pages: 14751), Publisher: NATURE RESEARCH, Berlin, Germany
    Status:
    Published
    DOI:
    10.1038/s41598-021-93982-3 – link to the publication

  3. Not Just Another Scaffolding Protein Family: The Multifaceted MPPs

    Authors:
    Agnieszka Chytła, Weronika Gajdzik-Nowak, Paulina Olszewska, Agnieszka Biernatowska , Aleksander F Sikorski, Aleksander Czogalla
    Academic press:
    Molecules (year: 2020, volume: 25, pages: 4954), Publisher: MDPI, Basel, Switzerland
    Status:
    Published
    DOI:
    10.3390/molecules25214954 – link to the publication

  4. High-Level Expression of Palmitoylated MPP1 Recombinant Protein in Mammalian Cells

    Authors:
    Agnieszka Chytła, Weronika Gajdzik-Nowak, Agnieszka Biernatowska, Aleksander F. Sikorski, Aleksander Czogalla
    Academic press:
    Membranes (year: 2021, volume: 11, pages: 715), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/membranes11090715 – link to the publication

  5. Interaction of membrane palmitoylated protein-1 with model lipid membranes

    Authors:
    Mohamed Elderdfi, Aleksander F. Sikorski
    Academic press:
    General Physiology and Biophysics (year: 2018, volume: 37, pages: 603–617), Publisher: AEPress, Bratislava, Slovakia
    Status:
    Published
    DOI:
    10.4149/gpb_2018029 – link to the publication

Articles in post-conference publications (3)

  1. High affinity interaction of MPP1 with flotillins in vitro

    Authors:
    Paulina Olszewska, Krzysztof Grzymajło, Aleksander Czogalla, Agnieszka Biernatowska
    Conference:
    43rd FEBS Congress Biochemistry Forever (year: 2018, pages: 370), Publisher: FEBS Press and John Wiley & Sons Ltd.
    Date:
    conference 07-12 lipca
    Status:
    Published

  2. Mapping of MPP1 palmitoylation sites using AcylPEGExchange (APE) method

    Authors:
    W. Gajdzik-Nowak, A. Chytła, A. Biernatowska, A. Czogalla
    Conference:
    44th FEBS Congress (year: 2019, pages: 353), Publisher: FEBS Press and John Wiley & Sons Ltd.
    Date:
    conference 06-11.07.2019
    Status:
    Published

  3. Mapping interaction site in MPP1 for flotillins

    Authors:
    P. Olszewska, K. Grzymajło, A. Czogalla, A. Biernatowska
    Conference:
    44th FEBS Congress (year: 2019, pages: 56), Publisher: FEBS Press and John Wiley & Sons Ltd.
    Date:
    conference 06-11.07.2019
    Status:
    Published

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