Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Studies of new funtionalized derivatives of flake graphene oxide using long-term spheroid culture towards selective uptake by cancer cells.

2016/21/B/ST5/01774

Keywords:

graphene oxide reduced graphene oxide modyfied form of graphene Lab-on-a-Chip cytotoxicity

Descriptors:

  • ST5_3: Surface modification
  • ST5_19:

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Politechnika Warszawska, Wydział Chemiczny

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Zbigniew Brzózka 

Number of co-investigators in the project: 9

Call: OPUS 11 - announced on 2016-03-15

Amount awarded: 743 880 PLN

Project start date (Y-m-d): 2017-02-10

Project end date (Y-m-d): 2020-02-09

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Mikroskop świetlny odwrócony z systemem kontroli temperatury i modułem zliczania komórek (69 000 PLN)
  2. System plazmowej aktywacji powierzchni elementów mikrosystemów bioanalitycznych (80 000 PLN)

Information in the final report

  • Publication in academic press/journals (6)
  • Book publications / chapters in book publications (2)
  1. Cytotoxic properties of graphene derivatives depending on origin and type of cell line
    Authors:
    Agnieszka Zuchowska, Bartlomiej Dabrowski, Elzbieta Jastrzebska, Marta MazurkiewiczPawlicka , Artur Malolepszy, Leszek Stobinski, Maciej Trzaskowski, Zbigniew Brzozka
    Academic press:
    Journal of Materials Research (rok: 2020, tom: 35, strony: 45302), Wydawca: Cambridge Core
    Status:
    Published
    DOI:
    10.1557/jmr.2020.201 - link to the publication
  2. 3D and 2D cell models in a novel microfluidic tool for evaluation of highly chemically and microbiologically pure graphene oxide (GO) as an effective drug carrier
    Authors:
    A. Zuchowska, A. Buta, B. Dabrowski, E. Jastrzebska, K. Zukowski, Z. Brzozka
    Academic press:
    Sensors and Actuators B: Chemical (rok: 2020, tom: 302, strony: 127064), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.snb.2019.127064 - link to the publication
  3. Different action of nanoencapsulated meso-tetraphenylporphyrin in breast spheroid co-culture and mono-culture under microfluidic conditions
    Authors:
    Agnieszka Zuchowska, Katarzyna Marciniak, Urszula Bazylinska, Elzbieta Jastrzebska, Kazimiera A.Wilk, Zbigniew Brzozka
    Academic press:
    Sensors and Actuators B (rok: 2018, tom: 275, strony: 69-77), Wydawca: ELSEVIER
    Status:
    Published
    DOI:
    10.1016/j.snb.2018.08.037 - link to the publication
  4. Nanoconjugates of graphene oxide derivatives and meso-tetraphenylporphyrin: A new avenue for anticancer photodynamic therapies - Cell-on-a-Chip analysis
    Authors:
    A. Zuchowska, A. Kasprzak, B. Dabrowski, K. Kaminska, M. Poplawska, Z. Brzozka
    Academic press:
    New Journal of Chemistry (rok: 2020, tom: 44, strony: 18770-18779), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/D0NJ04189K - link to the publication
  5. Functionalization of graphene: does the organic chemistry matter?
    Authors:
    Artur Kasprzak, Agnieszka Zuchowska, Magdalena Poplawska
    Academic press:
    Beilstein Journal of Organic Chemistry (rok: 2018, tom: 14, strony: 2018-2026), Wydawca: Beilstein-Institut
    Status:
    Published
    DOI:
    10.3762/bjoc.14.177 - link to the publication
  6. Well-defined graphene oxide as a potential component in lung cancer therapy
    Authors:
    Agnieszka Zuchowska, Elzbieta Jastrzebska, Marta Mazurkiewicz-Pawlicka, Artur Malolepszy, Leszek Stobinski, Maciej Trzaskowski, Zbigniew Brzozka
    Academic press:
    Current Cancer Drug Targets (rok: 2020, tom: 20, strony: 45303), Wydawca: Bentham Science
    Status:
    Published
    DOI:
    10.2174/1568009619666191021113807 - link to the publication
  1. Lab-on-a-chip systems for cellomics-materials and technology
    Authors:
    Kalinowska, D., Tokarska, K., Grabowska-Jadach, I., Dybko, A., Brzozka, Z.
    Book:
    Cardiac Cell Culture Technologies (rok: 2018, tom: -, strony: 23-53), Wydawca: Springer
    Status:
    Published
  2. Organ-on-a-chip Systems
    Authors:
    Szuplewska, A., Chudy, M., Brzozka, Z.
    Book:
    Cardiac Cell Culture Technologies (rok: 2018, tom: -, strony: 55-78), Wydawca: Springer
    Status:
    Published

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