Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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The impact of the oxidative stress-mediated activation of p66Shc signaling pathway on mitochondrial bioenergetics and reactive oxygen species level in human breast cancer cell lines MDA-MB-231 and MCF-7.

2016/21/N/NZ1/00278

Keywords:

p66Shc mitochondria oxidative stress reactive oxygen species breast cancer

Descriptors:

  • NZ1_2:
  • NZ1_1:

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polskiej Akademii Nauk

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Monika Prill 

Number of co-investigators in the project: 2

Call: PRELUDIUM 11 - announced on 2016-03-15

Amount awarded: 100 000 PLN

Project start date (Y-m-d): 2017-02-13

Project end date (Y-m-d): 2021-09-12

Project duration:: 55 months (the same as in the proposal)

Project status: Project settled

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (2)
  1. p66Shc Protein—Oxidative Stress Sensor or Redox Enzyme: Its Potential Role in Mitochondrial Metabolism of Human Breast Cancer
    Authors:
    Monika Prill, Vilma A. Sardão, Mateusz Sobczak, Dominika Nowis, Jedrzej Szymanski and Mariusz R. Wieckowski
    Academic press:
    Cancers (rok: 2024, tom: 16 (19), strony: 3324), Wydawca: MDPI
    Status:
    Submitted
    DOI:
    10.3390/cancers16193324 - link to the publication
  2. Ras, TrkB, and ShcA Protein Expression Patterns in Pediatric Brain Tumors
    Authors:
    Monika Prill, Agnieszka Karkucinska-Wieckowska, Magdalena Lebiedzinska-Arciszewska, Giampaolo Morciano, Agata Charzynska, Michal Dabrowski, Maciej Pronicki, Paolo Pinton, Wieslawa Grajkowska, Mariusz R Wieckowski
    Academic press:
    Journal of Clinical Medicine (rok: 2021, tom: 10, strony: 2219), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/jcm10102219 - link to the publication

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