Immunomodulatory activities of cathelicidin LL-37 and its amphipathic analogs in urinary tract infections
2016/21/N/NZ6/02213
Keywords
Descriptors
- NZ6_4: Bakteriologia
Panel
NZ6 – Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology
Host institution
Uniwersytet Medyczny w Białymstoku, Wydział Lekarski z Oddziałem Stomatologii i Oddziałem Nauczania w Języku Angielskim
Voivodeship: podlaskie
Principal investigator (from the host institution)
Number of co-investigators in the project: 3
Call
PRELUDIUM 11 – announced on 2016-03-15
- Amount awarded
- 149 160 PLN
- Project start date
- 2017-01-13
- Project end date
- 2021-07-12
- Project duration
- 54 months (the same as in the proposal)
- Project status
- Project settled
Project description
Download the project description in a pdf file
Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
Publication in academic press/journals (2)
-
Nanoantibiotics containing membrane-active human cathelicidin LL-37 or synthetic ceragenins attached to the surface of magnetic nanoparticles as novel and innovative therapeutic tools: current status and potential future applications
- Authors:
- Wnorowska Urszula, Fiedoruk Krzysztof, Piktel Ewelina, Prasad Suhanya Veronica, Sulik Magdalena, Janion Marianna, Daniluk Tamara, Savage Paul, Bucki Robert
- Academic press:
- Journal of Nanobiotechnology (year: 2020, volume: 18, pages: 18), Publisher: Springer Nature
- Status:
- Published
- DOI:
- 10.1186/s12951-019-0566-z – link to the publication
-
Use of ceragenins as a potential treatment for urinary tract infections
- Authors:
- Wnorowska Urszula, Piktel S.D. Ewelina, Durnaś Bonita, Fiedoruk Krzysztof, Savage Paul B., Bucki Robert
- Academic press:
- BMC Infectious Diseases (year: 2019, volume: 19,1, pages: Article number: 369, 13pp), Publisher: Springer Nature
- Status:
- Published
- DOI:
- 10.1186/s12879-019-3994-3 – link to the publication
Articles in post-conference publications (4)
-
A place for ceragenis and LL-37 peptide in treatment of urinary tract infections
- Authors:
- Urszula Wnorowska, Ewelina Piktel, Bonita Durnaś, P. Savage, Mateusz Cieśluk, Piotr Deptuła, Robert Bucki.
- Conference:
- 3rd Gulf Congress of Clinical Microbiology & Infectious Diseases GCCMID (year: 2018, pages: 78), Publisher: Emirates Infectious Diseases Society
- Date:
- conference 7-10 Listopad
- Status:
- Published
-
Aktywność przeciwbakteryjna peptydu LL - 37 oraz ceragenin w modelu in vitro zakażenia układu moczowego
- Authors:
- Urszula Wnorowska, Ewelina Piktel, Paul B. Savage, Robert Bucki
- Conference:
- 60 Zjazd Naukowy Polskiego Towarzystwa Chemicznego (year: 2017, pages: 1118), Publisher: Polskie Towarzystwo Chemiczne
- Date:
- conference 17-21 wrzesień
- Status:
- Published
-
Activity of ceragenins against Escherichia coli strains involved in the urinary tract infections
- Authors:
- Gołaszewska Agnieszka, Wnorowska Urszula, Cieśluk Mateusz, Fiedoruk Krzysztof, Prasad Suhanya Veronica, Durnaś Bonita
- Conference:
- 14TH Bialystok International Medical Congress for Young Scientists (year: 2019, pages: 74), Publisher: Uniwersytet Medyczny w Białymstoku
- Date:
- conference 17.05-18.05.2019
- Status:
- Published
-
Synergistyczne oddziaływanie peptydu LL-37 i cerageniny CSA-131 w stosunku do klinicznych szczepów E. coli izolowanych od pacjentów z zakażeniem układu moczowego
- Authors:
- Urszula Wnorowska, Ewelina Piktel, Grzegorz Michalak, Paul B. Savage, Robert Bucki
- Conference:
- V Konferencja Związki Biologicznie Czynne: aktywność, struktura, synteza (year: 2017, pages: 87), Publisher: Uniwersytet w Białymstoku
- Date:
- conference 09-11 czerwca
- Status:
- Published