Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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Studies on molecular mechanism of antiviral activity of Chelidonium majus L. latex

2016/21/N/NZ6/00997

Keywords:

antiviral activity defense-related proteins medicinal plants

Descriptors:

  • NZ6_5: Virology
  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology
  • NZ2_3: Proteomics

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Oskar Musidlak 

Number of co-investigators in the project: 2

Call: PRELUDIUM 11 - announced on 2016-03-15

Amount awarded: 144 000 PLN

Project start date (Y-m-d): 2017-01-16

Project end date (Y-m-d): 2021-01-15

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (5)
  • Book publications / chapters in book publications (2)
  1. Przeciwwirusowe związki izolowane z roślin
    Authors:
    Robert Nawrot1, Alicja Warowicka, Oskar Musidlak, Martyna Węglewska, Sophia Bałdysz, Anna Goździcka-Józefiak
    Academic press:
    Postępy Biochemii (rok: 2020, tom: 66, strony: 45308), Wydawca: Polskie Towarzystwo Biochemiczne
    Status:
    Published
    DOI:
    10.18388/pb.2020_361 - link to the publication
  2. Which Plant Proteins Are Involved in Antiviral Defense? Review on In Vivo and In Vitro Activities of Selected Plant Proteins against Viruses.
    Authors:
    Musidlak Oskar, Robert Nawrot, Anna Goździcka-Józefiak
    Academic press:
    International Journal of Molecular Sciences (rok: 2017, tom: 18, strony: -), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms18112300 - link to the publication
  3. Combined Protein and Alkaloid Research of Chelidonium majus Latex Reveals CmMLP1 Accompanied by Alkaloids with Cytotoxic Potential to Human Cervical Carcinoma Cells
    Authors:
    Robert Nawrot, Alicja Warowicka, Piotr Józef Rudzki, Oskar Musidlak, Katarzyna Magdalena Dolata, Jacek Musijowski, Elżbieta Urszula Stolarczyk, Anna Goździcka-Józefiak
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 22, strony: 45307), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms222111838 - link to the publication
  4. Protoberberine compounds extracted from Chelidonium majus L. as novel natural photosensitizers for cancer therapy
    Authors:
    Alicja Warowicka, Łukasz Popenda, Grażyna Bartkowiak, Oskar Musidlak, Jagoda Litowczenko-Cybulska, Dorota Kuźma, Robert Nawrot, Stefan Jurga, Anna Goździcka-Józefiak
    Academic press:
    Phytomedicine (rok: 2019, tom: 64, strony: -), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.phymed.2019.152919 - link to the publication
  5. The Activity of Chelidonium majus L. Latex and Its Components on HPV Reveal Insights into the Antiviral Molecular Mechanism
    Authors:
    Oskar Musidlak, Alicja Warowicka, Justyna Broniarczyk, Damian Adamczyk, Anna Goździcka-Józefiak, Robert Nawrot
    Academic press:
    International Journal of Molecular Sciences (rok: 2022, tom: 23, strony: 45321), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms23169241 - link to the publication
  1. Traditional use and perspectives for the application of plant latex and its constituents in agriculture, medicine and industry—A follow-up of ABR volume 93 Latex, laticifers and their molecular components from functions to possible applications"
    Authors:
    Robert Nawrot, Oskar Musidlak, Sophia Bałdysz, Martyna Węglewska, Alicja Warowicka, Anna Goździcka- Józefiak
    Book:
    Advances in Botanical Research (Volume 100): Past, Current and Future Topics (rok: 2021, tom: 100, strony: 301-327), Wydawca: Academic Press
    Status:
    Published
  2. Plant latex proteins and their functions
    Authors:
    Oskar Musidlak, Sophia Bałdysz, Michalina Krakowiak, Robert Nawrot
    Book:
    Latex, Laticifers and Their Molecular Components: From Functions to Possible Applications (rok: 2020, tom: 93, strony: 55-97), Wydawca: Academic Press
    Status:
    Published

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