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Information of the project and the call

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Physiological characterization of the HtrA4 protease, including its role in apoptosis.

2016/21/N/NZ3/03263

Keywords:

HtrA proteases HtrA4 protein apoptosis necrosis

Descriptors:

  • NZ3_2: Cell physiology
  • NZ3_3: Apoptosis
  • NZ1_1: Molecular biology

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Uniwersytet Gdański, Wydział Biologii

woj. pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Tomasz Wenta 

Number of co-investigators in the project: 2

Call: PRELUDIUM 11 - announced on 2016-03-15

Amount awarded: 99 996 PLN

Project start date (Y-m-d): 2017-03-07

Project end date (Y-m-d): 2019-03-06

Project duration:: 24 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (4)
  • Articles in post-conference publications (6)
  1. HtrA4 Protease Promotes Chemotherapeutic-Dependent Cancer Cell Death
    Authors:
    Tomasz Wenta, Michal Rychlowski, Miroslaw Jarzab, Barbara Lipinska
    Academic press:
    Cells (rok: 2019, tom: 8, strony: 45312), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cells8101112 - link to the publication
  2. Immune response against HtrA proteases in children with cutaneous mastocytosis
    Authors:
    Joanna Renke, Sabina Kędzierska-Mieszkowska, Magdalena Lange, Bogusław Nedoszytko, Anna Liberek, Katarzyna Plata-Nazar, Marcin Renke, Tomasz Wenta, Dorota Żurawa-Janicka, Joanna Skórko-Glonek, Barbara Lipińska
    Academic press:
    Acta Biochimica Polonica (rok: 2018, tom: 65, strony: 45299), Wydawca: Acta Biochimica Polonica
    Status:
    Published
    DOI:
    10.18388/abp.2018_2623 - link to the publication
  3. HtrA3 is a cellular partner of cytoskeleton proteins and TCP1α chaperonin
    Authors:
    Tomasz Wenta, Dorota Zurawa-Janicka, Michal Rychlowski, Miroslaw Jarzab, Przemyslaw Glaza, Andrea Lipinska, Krystyna Bienkowska-Szewczyk, Anna Herman-Antosiewicz, Joanna Skorko-Glonek, Barbara Lipinska
    Academic press:
    Journal of Proteomics (rok: 2018, tom: 177, strony: 88-111), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jprot.2018.02.022 - link to the publication
  4. Cellular substrates and pro-apoptotic function of the human HtrA4 protease
    Authors:
    Tomasz Wenta, Miroslaw Jarzab, Michal Rychlowski, Monika Borysiak, Anna Latala, Dorota Zurawa-Janicka, Anna Filipek, Barbara Lipinska
    Academic press:
    Journal of Proteomics (rok: 2019, tom: 209, strony: 45310), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jprot.2019.103505 - link to the publication
  1. HtrA4 interacts with pro-apoptotic and cytoskeleton proteins, and promotes chemotherapeutic-induced death of cancer cells
    Authors:
    Tomasz Wenta, Monika Borysiak, Anna Latala, Małgorzata Sakowicz, Barbara Lipinska
    Conference:
    VI International Caparica Conference on Analytical Proteomics 2019 (rok: 2019, ), Wydawca: University NOVA of Lisbon
    Data:
    konferencja 8-11.07
    Status:
    Published
  2. HtrA4 promuje apoptozę komórek gruczolakoraka płuc traktowanych etopozydem
    Authors:
    Anna Latała, Tomasz Wenta, Barbara Lipińska
    Conference:
    IV Studencka Konferencja Biologii Medycznej "Biofuzje" (rok: 2019, ), Wydawca: Uniwersytet Warszawski
    Data:
    konferencja 24-26.05
    Status:
    Published
  3. Involvement of the HtrA4 serine protease in promotion of etoposide-dependent death of lung cancer cells
    Authors:
    Anna Latala, Tomasz Wenta, Barbara Lipinska
    Conference:
    II Konferencja Doktorantów Pomorza BioMED Session (rok: 2018, ), Wydawca: Katedra Biologii Molekularnej Uniwersytetu Gdańskiego
    Data:
    konferencja 7,12
    Status:
    Published
  4. Identification of the cellular partners of the HtrA4 human protease
    Authors:
    Monika Borysiak, Tomasz Wenta, Barbara Lipinska
    Conference:
    II Konferencja Doktorantów Pomorza BioMed Session (rok: 2018, ), Wydawca: Katedra Biologii Molekularnej Uniwersytetu Gdańskiego
    Data:
    konferencja 7,12
    Status:
    Published
  5. Identification of the cellular partners of the proapoptotic HtrA4 protease
    Authors:
    Tomasz Wenta, Monika Borysiak, Anna Latała, Bartosz Isański, Karol Jasiński, Małgorzata Sakowicz, Barbara Lipińska
    Conference:
    3rd Congress of Polish Biosciences BIO2018 Through interdisciplinary approach into new solutions" (rok: 2018, ), Wydawca: Acta Biochimica Polonica
    Data:
    konferencja 18-21.09
    Status:
    Published
    DOI:
    link to the publication
  6. Physiological characterization of the proapoptotic HtrA4 protease
    Authors:
    Tomasz Wenta, Monika Borysiak, Anna Latała, Karol Jasiński, Małgorzata Sakowicz, Barbara Lipińska
    Conference:
    15TH HORIZONS IN MOLECULAR BIOLOGY. International PhD Student Symposium and Career Fair for Life Sciences (rok: 2018, ), Wydawca: CUVILLIER VERLAG
    Data:
    konferencja 10-13.09
    Status:
    Published

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