Elaboration and characteristics of biocomposites with anti-virulent and anti-bacterial properties against Pseudomonas aeruginosa
2016/21/B/NZ6/01157
Keywords
Descriptors
- NZ6_4: Bakteriologia
- NZ6_5: Wirusologia
- ST5_11: Synteza biomateriałów
Panel
NZ6 – Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology
Host institution
Uniwersytet Wrocławski, Wydział Nauk Biologicznych
Voivodeship: dolnośląskie
Principal investigator (from the host institution)
Number of co-investigators in the project: 11
Call
OPUS 11 – announced on 2016-03-15
- Amount awarded
- 1 480 600 PLN
- Project start date
- 2017-05-19
- Project end date
- 2022-05-18
- Project duration
- 60 months (the same as in the proposal)
- Project status
- Project settled
Project description
Download the project description in a pdf file
Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Equipment purchased [PL]
- zestaw dwóch kuwet kwarcowych pozwalających na ocenę dyfuzji w insertach z zastosowaniem techniki interferometrii laserowej z układem stabilizującym temperaturę. Cost: 50 000 PLN
- System do Real-Time qPCR typu CFX96 Touch System. Cost: 150 000 PLN
- czytnik mikropłytek VARIOSKAN LUX THERMO. Cost: 140 000 PLN
- kamera ORCA-Flasch CMOS do mikroskopu konfokalnego. Cost: 150 000 PLN
- zestaw laserów i MCOMB.
Information in the final report
Publication in academic press/journals (17)
-
Editorial Special Issue: Bacteriophages and Biofilms
- Authors:
- Zuzanna Drulis-Kawa, Barbara Maciejewska
- Academic press:
- Viruses (year: 2021, volume: 13, pages: 257), Publisher: MDPI
- Status:
- Published
- DOI:
- 10.3390/v13020257 – link to the publication
-
Antitumor Activity of Pt(II), Ru(III) and Cu(II) Complexes
- Authors:
- Katarzyna Gałczynska, Zuzanna Drulis-Kawa and Michał Arabski
- Academic press:
- Molecules (year: 2020, volume: 25, pages: Jul 31;25(15):3492), Publisher: MDPI
- Status:
- Published
- DOI:
- 10.3390/molecules25153492. – link to the publication
-
Modelling experimentally measured of ciprofloxacin antibiotic diffusion in Pseudomonas aeruginosa biofilm formed in artificial sputum medium
- Authors:
- Tadeusz Kosztołowicz, Ralf Metzler, Sławomir Wa̡sik, Michał Arabski
- Academic press:
- PlosONE (year: 2020, volume: 15, pages: Dec 3;15(12):e0243003.), Publisher: PLOS
- Status:
- Published
- DOI:
- 10.1371/journal.pone.0243003 – link to the publication
-
Preparation of a New Biocomposite Designed for Cartilage Grafting with Antibiofilm Activity
- Authors:
- Sara Targonska, Justyna Rewak-Soroczynska, Agata Piecuch, Emil Paluch, Damian Szymanski, and Rafal J. Wiglusz
- Academic press:
- ACS Omega (year: 2020, volume: 38, pages: 5, 38, 24546–24557), Publisher: ACS Publications
- Status:
- Published
- DOI:
- 10.1021/acsomega.0c03044 – link to the publication
-
The Influence of Ozonated Olive Oil-Loaded and Copper-Doped Nanohydroxyapatites on Planktonic Forms of Microorganisms
- Authors:
- Wojciech Zakrzewski, Maciej Dobrzynski, Joanna Nowicka, Magdalena Pajaczkowska, Maria Szymonowicz, Sara Targonska, Paulina Sobierajska, Katarzyna Wiglusz, Wojciech Dobrzynski, Adam Lubojanski, Sebastian Fedorowicz, Zbigniew Rybak and Rafal J. Wiglusz
- Academic press:
- Nanomaterials (year: 2020, volume: 10,, pages: 1997), Publisher: MDPI
- Status:
- Published
- DOI:
- 10.3390/nano10101997 – link to the publication
-
The In Vitro Anti-Pseudomonal Activity of Cu2+, Strawberry Furanone, Gentamicin, and Lytic Phages Alone and in Combination: Pros and Cons
- Authors:
- Agata Dorotkiewicz-Jach, Pawel Markwitz, Zuzanna Drulis-Kawa
- Academic press:
- International Journal of Molecular Sciences (year: 2021, volume: 22, pages: 11562), Publisher: MDPI
- Status:
- Published
- DOI:
- 10.3390/ijms22189830 – link to the publication
-
Targeting biofilms using phages and their enzymes
- Authors:
- Joana Azeredo, Pilar Garcıa, Zuzanna Drulis-Kawa
- Academic press:
- Current Opinion in Biotechnology (year: 2021, volume: 68, pages: 251–261), Publisher: Elsevier Ltd.
- Status:
- Published
- DOI:
- 10.1016/j.c – link to the publication
-
Complex Signaling Networks Controlling Dynamic Molecular Changes in Pseudomonas aeruginosa Biofilm
- Authors:
- Grzegorz Guła, Agata Dorotkiewicz-Jach, Kamila Korzekwa, Miguel A. Valvano, Zuzanna Drulis-Kawa
- Academic press:
- Current Medicinal Chemistry (year: 2019, volume: 26, pages: 1979-1993), Publisher: Bentham Science Publishers
- Status:
- Published
- DOI:
- 10.2174/0929867325666180912110151 – link to the publication
-
Quenching of the Eu3+ Luminescence by Cu2+ Ions in the Nanosized Hydroxyapatite Designed for Future Bio-Detection
- Authors:
- Katarzyna Szyszka, Sara Targonska, Agnieszka Lewinska, Adam Watras, Rafal J. Wiglusz
- Academic press:
- Nanomaterials (year: 2021, volume: 11, pages: 464), Publisher: MDPI
- Status:
- Published
-
Multifunctionality of Nanosized Calcium Apatite Dual-Doped with Li+/Eu3+ Ions Related to Cell Culture Studies and Cytotoxicity Evaluation In Vitro
- Authors:
- Paulina Sobierajska, Blazej Pozniak, Marta Tikhomirov, Julia Miller, Lucyna Mrowczynska, Agata Piecuch, Justyna Rewak-Soroczynska, Agata Dorotkiewicz-Jach, Zuzanna Drulis-Kawa, Rafal J. Wiglusz
- Academic press:
- Biomolecules (year: 2021, volume: 11, pages: 1388), Publisher: MDPI
- Status:
- Published
- DOI:
- 10.3390/biom11091388 – link to the publication
-
New Approach to Antifungal Activity of Fluconazole Incorporated into the Porous 6-Anhydro--L-Galacto--D -Galactan Structures Modified with Nanohydroxyapatite for Chronic-Wound Treatments—In Vitro Evaluation
- Authors:
- Justyna Rewak-Soroczynska, Paulina Sobierajska, Sara Targonska, Agata Piecuch, Lukasz Grosman, Jaroslaw Rachuna, SlawomirWasik, Michal Arabski, Rafal Ogorek and Rafal J. Wiglusz
- Academic press:
- International Journal of Molecular Sciences (year: 2021, volume: 22, pages: 3112), Publisher: MDPI
- Status:
- Published
- DOI:
- 10.3390/ijms22063112 – link to the publication
-
Selective cytotoxicity and antifungal properties of copper(II) and cobalt(II) complexes with imidazole-4-acetate anion or 1-allylimidazole
- Authors:
- Katarzyna Gałczyńska, Karol Ciepluch, Łukasz Madej, Krystyna Kurdziel, Barbara Maciejewska, Zuzanna Drulis-Kawa, Aneta Węgierek-Ciuk Anna Lankoff, Michał Arabski
- Academic press:
- Scientific Reports (year: 2019, volume: Jul 5;9(1), pages: Jul 5;9(1):9777.), Publisher: Springer Nature
- Status:
- Published
- DOI:
- 10.1038/s41598-019-46224-6. – link to the publication
-
Applications of bacteriophages versus phage enzymes to combat and cure bacterial infections: an ambitious and also a realistic application?
- Authors:
- Barbara Maciejewska, Tomasz Olszak, Zuzanna Drulis-Kawa
- Academic press:
- Applied Microbiology and Biotechnology (year: 2018, volume: 102, pages: 2563–2581), Publisher: Springer
- Status:
- Published
- DOI:
- 10.1007/s00253-018-8811-1 – link to the publication
-
A Study of the Impact of Graphene Oxide on Viral Infection Related to A549 and TC28a2 Human Cell Lines
- Authors:
- Piotr Kuropka, Maciej Dobrzynski, Barbara Bazanow, Dominika Stygar, Tomasz Gebarowski, Anna Leskow, Malgorzata Tarnowska, Katarzyna Szyszka, Malgorzata Malecka, Nicole Nowak, Wieslaw Strek, Rafal J.Wiglusz
- Academic press:
- Materials (year: 2021, volume: 14, pages: 7788), Publisher: MDPI
- Status:
- Published
-
Outer Membrane Vesicles (OMVs) of Pseudomonas aeruginosa Provide Passive Resistance but Not Sensitization to LPS-Specific Phages
- Authors:
- Daria Augustyniak, Tomasz Olszak, Zuzanna Drulis-Kawa
- Academic press:
- Viruses (year: 2022, volume: 14, pages: 121), Publisher: MDPI
- Status:
- Published
- DOI:
- 10.3390/v14010121 – link to the publication
-
Culture media composition influences the antibacterial effect of silver, cupric, and zinc ions against Pseudomonas aeruginosa
- Authors:
- Justyna Rewak-Soroczynska, Agata Dorotkiewicz-Jach *, Zuzanna Drulis-Kawa, Rafal J. Wiglusz
- Academic press:
- Biomolecules (year: 2022, volume: 12(7), pages: 963), Publisher: MDPI
- Status:
- Published
- DOI:
- 10.3390/biom12070963 – link to the publication
-
The Application of Impedance Spectroscopy for Pseudomonas Biofilm Monitoring during Phage Infection
- Authors:
- Grzegorz Guła, Paulina Szymanowska, Tomasz Piasecki , Sylwia Góras, Teodor Gotszalk and Zuzanna Drulis-Kawa
- Academic press:
- Viruses (year: 2020, volume: 12, pages: Apr 7;12(4):407), Publisher: MDPI
- Status:
- Published
- DOI:
- 10.3390/v12040407 – link to the publication
Articles in post-conference publications (1)
-
Przegląd badań aktywności biologicznych jonów lantanowców
- Authors:
- Justyna Rewak-Soroczyńska, Agata Dorotkiewicz-Jach, Rafał J. Wiglusz
- Conference:
- XIV Interdyscyplinarna Konferencja Naukowa TYGIEL 2022 Interdyscyplinarność kluczem do rozwoju konferencja Lublin/online (year: 2022, pages: 162-167), Publisher: Wydawnictwo Naukowe TYGIEL, ul. Głowackiego 35/348, 20-060 Lublin
- Date:
- conference 24-27.03.2022
- Status:
- Published