Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Effect of Zearalenone on hepatocytes of cows with clinical and subclinical ketosis

2016/21/D/NZ9/01301

Keywords:

zearalenone micotoxins cow ketosis

Descriptors:

  • NZ9_11: Biohazards, biological containment, biosafety, biosecurity
  • NZ9_9: Environmental biotechnology

Panel:

NZ9 - Fundamentals of applied life sciences and biotechnology: agricultural, forestry, horticulture, animal production and fishery, food and nutrition sciences, industrial biosciences, environmental biotechnology and remediation

Host institution :

Uniwersytet Rolniczy im. Hugona Kołłątaja w Krakowie, Wydział Hodowli i Biologii Zwierząt

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Justyna Barć 

Number of co-investigators in the project: 2

Call: SONATA 11 - announced on 2016-03-15

Amount awarded: 605 650 PLN

Project start date (Y-m-d): 2017-02-07

Project end date (Y-m-d): 2021-06-06

Project duration:: 52 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Aparat do elektroforezy Mini-PROTEAN Tetra Cell z modułem do elektrotransfertu Mini Trans-Blot Module i zasilaczem PowerPac HC Power Supply (20 000 PLN)

Information in the final report

  • Publication in academic press/journals (1)
  • Articles in post-conference publications (7)
  1. Short Culture of Bovine Hepatocytes Biopsied from Dairy Cows as a Model for Toxicological Studies—CYP 1A1 Activity Response to Zearalenone Treatment
    Authors:
    Barć, J.; Flaga, J.; Kozubek, A.; Kowalski, Z.M.
    Academic press:
    International Journal of Molecular Sciences (rok: 2023, tom: 24, strony: 12344), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms241512344 - link to the publication
  1. Effect of zearalenone treatment on the expression of genes involved in lipids and glucose metabolism in bovine hepatocytes in vitro
    Authors:
    Justyna Barć, Magdalena Cich, Aleksandra Falasa, Zygmunt Maciej Kowalski
    Conference:
    6th International Conference of Cell Biology (rok: 2020, ), Wydawca: Jagiellonian University
    Data:
    konferencja 6-8.11.2020
    Status:
    Published
  2. The effect of zearalenone on CYP1A1 activity and mRNA expression in bovine hepatocytes
    Authors:
    Barć J., Dziubka A., Korytkowski Ł, Kowalski Z. M.
    Conference:
    XLVII Sesja Naukowa Sekcji Żywienia Zwierząt Komitetu Nauk Zootechnicznych i Akwakultury Polskiej Akademii Nauk (rok: 2018, ), Wydawca: -
    Data:
    konferencja 28-29.06.2018
    Status:
    Published
  3. Evaluation of the research model of in vitro culture of ketotic hepatocytes for toxicological and nutrigenomics studies
    Authors:
    J. Barć, Ł. Korytkowski, J. Flaga, O. Lasek, Z. M. Kowalski
    Conference:
    22nd European Society of Veterinary and Comparative Nutrition Congress (rok: 2018, ), Wydawca: ESVCN
    Data:
    konferencja 6-8.09.2018
    Status:
    Published
  4. Zearalenone affects lipid metabolism and induces inflammatory response in ketotic cows
    Authors:
    Barć J., Lasek O., Flaga J., Kowalski Z. M.
    Conference:
    ESVCN Congress 2021 (rok: 2021, ), Wydawca: -
    Data:
    konferencja 9-11.09.2021
    Status:
    Published
  5. Ketotic hepatocytes are less resistant to effect of zearalenone on expression of glucose metabolism
    Authors:
    J. Barć, O. Lasek, Z.M. Kowalski
    Conference:
    72nd Annual Meeting of the European Federation of Animal Science in Davos (rok: 2021, ), Wydawca: -
    Data:
    konferencja 30.08.2021-3.09.2021
    Status:
    Published
  6. Effect of zearalenone treatment on lipid metabolism in primary culture of ketotic bovine hepatocytes in vitro
    Authors:
    Barć J., Kowalski Z. M.
    Conference:
    XIIIth International Symposium on Ruminant Physiology (ISRP) (rok: 2019, ), Wydawca: Cambridge University Press
    Data:
    konferencja 44077
    Status:
    Published
  7. Evaluation of bovine hepatocytes culture from liver biopsies for toxicological and nutrigenomics studies
    Authors:
    J. Barć, E. Witkoś, Z.M. Kowalski
    Conference:
    XIV Conference of Young Researchers, Physiology and Biochemistry in Animal Nutrition (rok: 2017, ), Wydawca: Agencja Wydawniczo-Poligraficzna GIMPO, Mieczysław Pohl
    Data:
    konferencja 14-15.09.2017
    Status:
    Published

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