Effects of rapid weight gain on tylosin and enrofloxacin pharmacokinetics in turkeys - dosage modelling and validation based on pharmacokinetic-pharmacodynamic integration
2016/21/D/NZ7/01053
Keywords
Descriptors
- NZ7_14: Farmacja, farmakoterapia, farmakologia
- NZ7_11: Weterynaryjna ochrona zdrowia publicznego
Panel
NZ7 – Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology
Host institution
Uniwersytet Przyrodniczy we Wrocławiu, Wydział Medycyny Weterynaryjnej
Voivodeship: dolnośląskie
Principal investigator (from the host institution)
Number of co-investigators in the project: 3
Call
SONATA 11 – announced on 2016-03-15
- Amount awarded
- 214 730 PLN
- Project start date
- 2017-01-18
- Project end date
- 2020-01-17
- Project duration
- 36 months (the same as in the proposal)
- Project status
- Project settled
Project description
Download the project description in a pdf file
Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Equipment purchased [PL]
- komputer. Cost: 3 000 PLN
- program farmakokinetyczny Phoenix WinNonlin - dwuletnia licencja akademicka - 2017. Cost: 12 000 PLN
- program farmakokinetyczny Phoenix WinNonlin - dwuletnia licencja akademicka - 2019. Cost: 12 000 PLN
- urządzenie klimatyzacyjne. Cost: 2 900 PLN
- zasilacz awaryjny (UPS) o mocy wyjściowej 6000VA/5400W. Cost: 17 822 PLN
Information in the final report
Publication in academic press/journals (3)
-
Allometric analysis of tylosin tartrate pharmacokinetics in growing male turkeys
- Authors:
- Poźniak, B., Tikhomirov, M., Motykiewicz‐Pers, K., Bobrek, K., & Świtała, M.
- Academic press:
- Journal of Veterinary Science (year: 2020, volume: 21(3), pages: e35), Publisher: Korean Society of Veterinary Science
- Status:
- Published
- DOI:
- 10.4142/jvs.2020.21.e35 – link to the publication
-
The influence of age and body weight gain on enrofloxacin pharmacokinetics in turkeys—Allometric approach to dose optimization.
- Authors:
- Poźniak, B., Tikhomirov, M., Motykiewicz‐Pers, K., Bobrek, K., & Świtała, M.
- Academic press:
- Journal of Veterinary Pharmacology and Therapeutics (year: 2020, volume: 43(1), pages: 67-78), Publisher: Wiley
- Status:
- Published
- DOI:
- 10.1111/jvp.12833 – link to the publication
-
Allometric Optimization of Enrofloxacin Dosage in Growing Male Turkeys: Empirical Evidence for Improved Internal Exposure
- Authors:
- Poźniak, B., Tikhomirov, M., Motykiewicz‐Pers, K., Bobrek, K., & Świtała, M.
- Academic press:
- Antibiotics (year: 2020, volume: 9(12), pages: 925), Publisher: MDPI
- Status:
- Published
- DOI:
- 10.3390/antibiotics9120925 – link to the publication
Articles in post-conference publications (1)
-
Allometric scaling of enrofloxacin dosing as a tool to optimize antibiotic use in rapidly growing turkeys
- Authors:
- Błażej Poźniak, Marta Tikhomirov, Karolina Motykiewicz-Pers, Kamila Bobrek, Piotr Okoniewski, Marcin Świtała
- Conference:
- 14th International Congress of the European Association for Veterinary Pharmacology and Toxicology (year: 2018, pages: 58-59), Publisher: Wiley
- Date:
- conference 24-27.06.2018
- Status:
- Published