Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Design of SERS nanosensors for ex vivo detection of inflammatory state in blood vessels

2016/21/B/ST4/02151

Keywords:

surface-enhanced Raman sensors nanosized structures immunochemistry

Descriptors:

  • ST4_3: Molecular architecture and structure
  • ST4_2: Spectroscopic and spectrometric techniques
  • NZ5_5: Diagnostics in human diseases

Panel:

ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution :

Uniwersytet Jagielloński, Wydział Chemii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Kamilla Małek 

Number of co-investigators in the project: 9

Call: OPUS 11 - announced on 2016-03-15

Amount awarded: 861 660 PLN

Project start date (Y-m-d): 2017-02-16

Project end date (Y-m-d): 2021-08-15

Project duration:: 54 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Elementy optyczne, elektroniczne i mechaniczne do spektrometrów (2 szt.) (10 000 PLN)
  2. Komputer (lub laptop) (4 000 PLN)
  3. Monitory 2 szt. (996 PLN)
  4. laser o wzbudzeniu 632.8 nm z łącznikiem laserowym i światłowodami do spektrometru ramanowskiego (180 000 PLN)
  5. Licencja Microsoft Office.
  6. Oprogramowanie specjalistyczne (3 000 PLN)
  7. Komputer (6 000 PLN)
  8. Miernik mocy (22 328 PLN)
  9. Oprogramowanie specjalistyczne (2 szt.) (6 000 PLN)
  10. przenośne dyski o pojemności > 1 TB (3 szt.) (1 200 PLN)
  11. Sfera całkująca z komorą pomiarową dla rejestracji widm UV-Vis ciał stałych (28 000 PLN)

Information in the final report

  • Publication in academic press/journals (6)
  1. ImmunoSERS microscopy for the detection of smooth muscle cells in atherosclerotic plaques
    Authors:
    Ewelina Wiercigroch, Elzbieta Stepula, Lukasz Mateuszuk, Yuying Zhang, Malgorzata Baranska, Stefan Chlopicki, Sebastian Schlücker, Kamilla Malek
    Academic press:
    Biosensors and Bioelectronic (rok: 2019, tom: 133, strony: 79-85), Wydawca: ELSEVIER
    Status:
    Published
    DOI:
    10.1016/j.bios.2019.02.068 - link to the publication
  2. Intracellular pH – Advantages and pitfalls of surface-enhanced Ramanscattering and fluorescence microscopy – A review
    Authors:
    Aleksandra Jaworska, Kamilla Malek, Andrzej Kudelski
    Academic press:
    Spectrochimica Acta Part A: Molecular andBiomolecular Spectroscopy (rok: 2021, tom: 251, strony: 45302), Wydawca: ScienceDirect
    Status:
    Published
    DOI:
    10.1016/j.saa.2020.119410 - link to the publication
  3. Photocatalytical decoration of thin titania coatings with silver nanostructures provides a robust and reproducible SERS signal
    Authors:
    E. Wiercigroch, A. Kisielewska, A. Blat, A. Wislocka, I. Piwoński, K. Malek
    Academic press:
    Journal of Raman Spectroscopy (rok: 2019, tom: 50, strony: 1649-1660), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1002/jrs.5707 - link to the publication
  4. Photocatalytic deposition of plasmonic Au nanostructures on a semiconductor substrate to enhance Raman sensitivity
    Authors:
    Ewelina Wiercigroch, Pawel Swit, Aneta Kisielewska, Ireneusz Piwoński, Kamilla Malek
    Academic press:
    Applied Surface Science (rok: 2020, tom: 529, strony: 45302), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.apsusc.2020.147021 - link to the publication
  5. Dual-enhancement and dual-tag design for SERS-based sandwich immunoassays: Evaluation of a metal-metal effect in 3D architecture
    Authors:
    Ewelina Wiercigroch, Pawel Swit, Agnieszka Brzozka, Łukasz Pięta, Kamilla Malek
    Academic press:
    Microchimica Acta (rok: 2022, tom: 189, strony: 32), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s00604-021-05125-0 - link to the publication
  6. Detection of immune reaction by surface-enhanced Raman Spectroscopy: A mini-review
    Authors:
    Kamilla Malek, Ewelina Wiercigroch
    Academic press:
    Asian Journal of Physics (rok: 2022, tom: 31, strony: 45301), Wydawca: Anita Publications
    Status:
    Accepted for publication