Superparamagnetic nanoparticles labeled with beta- emitters for simultaneous internal radiotherapy and hyperthermia

2016/21/B/ST4/02133

Keywords

Descriptors

  • ST4_16: Chemia jądrowa i radiacyjna
  • ST5_12: Materiały "inteligentne" – materiały samoorganizujące się, materiały reagujące na bodźce zewnętrzne
  • ST5_10: Nanomateriały: nanocząstki, nanorurki

Panel

ST4 – Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution

Uniwersytet Warszawski, Wydział Chemii

Voivodeship: mazowieckie

Other projects carried out by the institution »

Principal investigator (from the host institution)

prof. Paweł Grzegorz Krysiński

Number of co-investigators in the project: 7

Call

OPUS 11 – announced on 2016-03-15

Amount awarded
866 920 PLN
Project start date
2017-04-20
Project end date
2021-04-19
Project duration
48 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Aparatura do badań hipertermicznych in-vitro. Cost: 160 000 PLN
  2. Ultrawirówka o prędkości obrotowej nie mniejszej niż 14000 obr/min. Cost: 25 000 PLN

Information in the final report

Publication in academic press/journals (6)

  1. Easy Synthesis and Characterization of Holmium-Doped SPIONs

    Authors:
    Magdalena Osial, Paulina Rybicka, Marek Pękała, Grzegorz Cichowicz, Michał K. Cyrański, Paweł Krysiński
    Academic press:
    Nanomaterials (year: 2018, volume: 8, pages: 430-445), Publisher: MDPI, Basel, Switzerland
    Status:
    Published
    DOI:
    10.3390/nano8060430 – link to the publication
  2. Synthesis and characterization of Gd3+- and Tb3+- doped iron oxide nanoparticles for possible endoradiotherapy and hyperthermia

    Authors:
    Aleksandra Rękorajska, Grzegorz Cichowicz, Michał K. Cyranski, Marek Pekala, Pawel Krysinski
    Academic press:
    J. Magn. Magn. Mat. (year: 2019, volume: 30, pages: 50-58), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jmmm.2019.01.102 – link to the publication
  3. Lanthanide-doped SPIONs bioconjugation with trastuzumab for potential multimodal anticancer activity and magnetic hyperthermia

    Authors:
    AWeronika Gawęda, Magdalena Osial, Michał Żuk, Marek Pękała, Aleksander Bilewicz and Pawel Krysinski
    Academic press:
    Nanomaterials (year: 2020, volume: 10, pages: 288), Publisher: MDPI AG
    Status:
    Published
    DOI:
    10.3390/nano10020288 – link to the publication
  4. Trastuzumab Modified Barium Ferrite Magnetic Nanoparticles Labeled with Radium-223: A New Potential Radiobioconjugate for Alpha Radioimmunotherapy

    Authors:
    W.Gawęda, Marek Pruszyński, E. Cędrowska, M.Rodak, A.Majkowska-Pilip, D. Gaweł, F.Bruchertseifer, A.Morgenstern, A.Bilewicz
    Academic press:
    Nanomaterials (year: 2020, volume: 10, pages: 2067), Publisher: MDPI
    Status:
    Published
  5. Trastuzumab Conjugated Superparamagnetic Iron Oxide Nanoparticles Labeled with 225Ac as a Perspective Tool for Combined α‐ Radioimmunotherapy and Magnetic Hyperthermia of HER2‐Positive Breast Cancer

    Authors:
    Edyta Cędrowska, Marek Pruszyński, Weronika Gawęda, Michał Żuk, Paweł Krysiński, Frank Bruchertseifer, Alfred Morgenstern , Maria‐Argyro Karageorgou, Penelope Bouziotis and Aleksander Bilewicz
    Academic press:
    Molecules (year: 2020, volume: 25, pages: 1025), Publisher: MDPI AG
    Status:
    Published
    DOI:
    10.3390/molecules25051025 – link to the publication
  6. Synthesis and Characterization of Tb-Doped Nanoferrites

    Authors:
    Aleksandra Rękorajska, Grzegorz Cichowicz, Michal K. Cyranski, Michal Grden, Marek Pekala, Gary J. Blanchard, Pawel Krysinski
    Academic press:
    ChemNanoMat (IF za 2016 rok) (year: 2018, volume: 4, pages: 231-242), Publisher: 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim
    Status:
    Published
    DOI:
    10.1002/cnma.201700344 – link to the publication

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Graphic design and implementation: Jakub Piotrowski