Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Optimization of parameters for evaluation of cardiomyogenesis efficacy in human cardiac mesenchymal stromal cells, during differentiation process, after treatment with human induced pluripotent stem cell derived extracellular vesicles.

2016/21/N/NZ3/00363

Keywords:

induced pluripotent stem cells extracellular vesicles cardiomyogenesis ion channels membrane potential regenerative medicine

Descriptors:

  • NZ3_8: Stem cell biology

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Katarzyna Kmiotek-Wasylewska 

Number of co-investigators in the project: 2

Call: PRELUDIUM 11 - announced on 2016-03-15

Amount awarded: 148 920 PLN

Project start date (Y-m-d): 2017-02-07

Project end date (Y-m-d): 2020-02-06

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Automatyczny licznik komórkowy Countess II FL (30 000 PLN)

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (3)
  1. Induced pluripotent stem cell-derived extracellular vesicles enriched with miR-126 induce proangiogenic properties of endothelial cells and promote ischemic tissue repair
    Authors:
    Katarzyna Kmiotek-Wasylewska, Anna Łabędź-Masłowska, Sylwia Bobis-Wozowicz, Elżbieta Karnas, Sylwia Noga, Małgorzata Sekuła-Stryjewska, Olga Woźnicka, Zbigniew Madeja, Buddhadeb Dawn, Ewa. K. Zuba-Surma
    Academic press:
    The FASEB Journal (rok: 2023, tom: n.a, strony: n.a), Wydawca: Wiley
    Status:
    Submitted
  2. Anti‑inflammatory, Anti‑fibrotic and Pro‑cardiomyogenic Effects of Genetically Engineered Extracellular Vesicles Enriched in miR‑1 and miR‑199a on Human Cardiac Fibroblasts
    Authors:
    Katarzyna Kmiotek-Wasylewska, Sylwia Bobis-Wozowicz, Elżbieta Karnas, Monika Orpel, Olga Woźnicka, Zbigniew Madeja, Buddhadeb Dawn and Ewa K. Zuba-Surma
    Academic press:
    Stem Cell Reviews and Reports (rok: 2023, tom: 19, strony: 2756–2773), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s12015-023-10621-2 - link to the publication
  1. Impact of extracellular vesicles from genetically modified human iPS cells on cardiac cells differentiation in vitro
    Authors:
    K. Kmiotek, S. Bobis-Wozowicz, E. Karnas, Z. Madeja, E. K. Zuba-Surma
    Conference:
    FEBS Conference 2017 (rok: 2017, ), Wydawca: Wiley Online Library
    Data:
    konferencja 10.09-14.09
    Status:
    Published
  2. Procardiomyogenic and proangiogenic properties of extracellular vesicles derived from genetically modified human induced pluripotent stem cells
    Authors:
    K. Kmiotek-Wasylewska, S. Bobis-Wozowicz, E. Karnas, Z. Madeja1, EK. Zuba-Surma
    Conference:
    ISEV 2018 (rok: 2018, ), Wydawca: Tylor & Francis Group
    Data:
    konferencja 02.05-06.05
    Status:
    Published
  3. Extracellular vesicles derived from genetically modified human induced pluripotent stem cells enhance cardiomyogenesis and angiogenesis in vitro and in vivo
    Authors:
    K. Kmiotek-Wasylewska, S. Bobis-Wozowicz, A. Labedz- Maslowska, E. Karnas, Z. Madeja, E. Zuba-Surma
    Conference:
    ISEV 2019 (rok: 2019, ), Wydawca: Tylor & Francis Group
    Data:
    konferencja 24.04-28.04
    Status:
    Published