Optimization of parameters for evaluation of cardiomyogenesis efficacy in human cardiac mesenchymal stromal cells, during differentiation process, after treatment with human induced pluripotent stem cell derived extracellular vesicles.
2016/21/N/NZ3/00363
Keywords
Descriptors
- NZ3_8: Komórki macierzyste
Panel
NZ3 – Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology
Host institution
Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii
Voivodeship: małopolskie
Principal investigator (from the host institution)
Number of co-investigators in the project: 2
Call
PRELUDIUM 11 – announced on 2016-03-15
- Amount awarded
- 148 920 PLN
- Project start date
- 2017-02-07
- Project end date
- 2020-02-06
- Project duration
- 36 months (the same as in the proposal)
- Project status
- Project settled
Project description
Download the project description in a pdf file
Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Equipment purchased [PL]
- Automatyczny licznik komórkowy Countess II FL. Cost: 30 000 PLN
Information in the final report
Publication in academic press/journals (1)
-
Anti‑inflammatory, Anti‑fibrotic and Pro‑cardiomyogenic Effects of Genetically Engineered Extracellular Vesicles Enriched in miR‑1 and miR‑199a on Human Cardiac Fibroblasts
- Authors:
- Katarzyna Kmiotek-Wasylewska, Sylwia Bobis-Wozowicz, Elżbieta Karnas, Monika Orpel, Olga Woźnicka, Zbigniew Madeja, Buddhadeb Dawn and Ewa K. Zuba-Surma
- Academic press:
- Stem Cell Reviews and Reports (year: 2023, volume: 19, pages: 2756–2773), Publisher: Springer
- Status:
- Published
- DOI:
- 10.1007/s12015-023-10621-2 – link to the publication
Articles in post-conference publications (3)
-
Impact of extracellular vesicles from genetically modified human iPS cells on cardiac cells differentiation in vitro
- Authors:
- K. Kmiotek, S. Bobis-Wozowicz, E. Karnas, Z. Madeja, E. K. Zuba-Surma
- Conference:
- FEBS Conference 2017 (year: 2017, pages: 369), Publisher: Wiley Online Library
- Date:
- conference 10.09-14.09
- Status:
- Published
-
Extracellular vesicles derived from genetically modified human induced pluripotent stem cells enhance cardiomyogenesis and angiogenesis in vitro and in vivo
- Authors:
- K. Kmiotek-Wasylewska, S. Bobis-Wozowicz, A. Labedz- Maslowska, E. Karnas, Z. Madeja, E. Zuba-Surma
- Conference:
- ISEV 2019 (year: 2019, pages: 303-304), Publisher: Tylor & Francis Group
- Date:
- conference 24.04-28.04
- Status:
- Published
-
Procardiomyogenic and proangiogenic properties of extracellular vesicles derived from genetically modified human induced pluripotent stem cells
- Authors:
- K. Kmiotek-Wasylewska, S. Bobis-Wozowicz, E. Karnas, Z. Madeja1, EK. Zuba-Surma
- Conference:
- ISEV 2018 (year: 2018, pages: 63), Publisher: Tylor & Francis Group
- Date:
- conference 02.05-06.05
- Status:
- Published