The role of the HtrA protein in the Helicobacter pylori cell
2016/21/B/NZ2/01775
Keywords
Descriptors
- NZ2_2: Genomika, transkryptomika i epigenomika
- NZ2_3: Proteomika
- NZ2_9: Biologia systemowa
Panel
NZ2 – Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology
Host institution
Uniwersytet Gdański, Wydział Biologii
Voivodeship: pomorskie
Principal investigator (from the host institution)
Number of co-investigators in the project: 5
Call
OPUS 11 – announced on 2016-03-15
- Amount awarded
- 851 300 PLN
- Project start date
- 2017-02-27
- Project end date
- 2021-08-26
- Project duration
- 54 months (the same as in the proposal)
- Project status
- Project settled
Project description
Download the project description in a pdf file
Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Equipment purchased [PL]
- Komora do jałowej pracy.
- Mini-wirówka laboratoryjna.
- Program do analizy dwukierunkowych elektroforegramów, wliczając DIGE. Cost: 65 000 PLN
- Spektrofotometr Vis.
- System do hodowli bakterii w warunkach o regulowanym stężeniu tlenu. Cost: 40 000 PLN
- System dokumentacji żeli i blotów. Cost: 160 000 PLN
Information in the final report
Publication in academic press/journals (6)
-
Importance of two PDZ domains for the proteolytic and chaperone activities of Helicobacter pylori serine protease HtrA
- Authors:
- 17)Zarzecka, U., Matkowska, D., Backert, S., Skorko-Glonek, J
- Academic press:
- Cellular Microbiology (year: 2021, volume: Vol. 23, Issue4, pages: article Number: e13299), Publisher: Wiley
- Status:
- Published
- DOI:
- 10.1111/cmi.13299 – link to the publication
-
Extracellular HtrA serine proteases: An emerging new strategy in bacterial pathogenesis.
- Authors:
- Backert S, Bernegger S, Skórko-Glonek J, Wessler S
- Academic press:
- Cellular Microbiology (year: 2018, volume: 20(6):e12845, pages: nie dotyczy), Publisher: John Wiley & Sons Ltd
- Status:
- Published
- DOI:
- 10.1111/cmi.12845 – link to the publication
-
Properties of the HtrA Protease From Bacterium Helicobacter pylori Whose Activity Is Indispensable for Growth Under Stress Conditions
- Authors:
- Zarzecka U, Modrak-Wójcik A, Figaj D, Apanowicz M, Lesner A, Bzowska A, Lipinska B, Zawilak-Pawlik A, Backert S, Skorko-Glonek J.
- Academic press:
- Frontiers in Microbiology (year: 2019, volume: 10, pages: Article no. 961), Publisher: FRONTIERS MEDIA SA, AVENUE DU TRIBUNAL FEDERAL 34, LAUSANNE, CH-1015, SWITZERLAND
- Status:
- Published
- DOI:
- 10.3389/fmicb.2019.00961 – link to the publication
-
Functional analysis and cryo-electron microscopy of Campylobacter jejuni serine protease HtrA
- Authors:
- 16)Zarzecka, U., Grinzato, A., Kandiah, E., Cysewski, D., Berto, P., Skorko-Glonek, J., Zanotti, G., Backert, S
- Academic press:
- Gut Microbes (year: 2020, volume: Vol. 12, pages: Article: 1810532), Publisher: Taylor & Francis
- Status:
- Published
- DOI:
- 10.1080/19490976.2020.1810532 – link to the publication
-
Establishment of serine protease htrA mutants in Helicobacter pylori is associated with secA mutations
- Authors:
- Zawilak-Pawlik A, Zarzecka U, Żyła-Uklejewicz D, Lach J, Strapagiel D, Tegtmeyer N, Böhm M, Backert S, Skorko-Glonek J.
- Academic press:
- Scientific Reports (year: 2019, volume: 9, pages: Article Number: 11794), Publisher: NATURE PUBLISHING GROUP, MACMILLAN BUILDING, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
- Status:
- Published
- DOI:
- 10.1038/s41598-019-48030-6 – link to the publication
-
Chaperone activity of serine protease HtrA of Helicobacter pylori as a crucial survival factor under stress conditions.
- Authors:
- Zarzecka U, Harrer A, Zawilak-Pawlik A, Skorko-Glonek J, Backert S.
- Academic press:
- Cell Communication and Signaling (year: 2019, volume: Vol:17 Iss:1, pages: 161), Publisher: BioMed Central Ltd. Part of Springer Nature
- Status:
- Published
- DOI:
- 10.1186/s12964-019-0481-9 – link to the publication