The impact of intracellular distribution and endocytic transport of lymphotoxin beta receptor (LTbetaR) on its signaling

2016/21/B/NZ3/03637

Keywords

Descriptors

  • NZ3_7: Przekaźnictwo sygnału
  • NZ3_1: Biologia komórki

Panel

NZ3 – Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Voivodeship: mazowieckie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr Magdalena Maria Banach-Orłowska

Number of co-investigators in the project: 5

Call

OPUS 11 – announced on 2016-03-15

Amount awarded
996 125 PLN
Project start date
2017-03-31
Project end date
2020-12-30
Project duration
45 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (3)

  1. Clathrin- and dynamin-dependent endocytosis limits canonical NF-κB signaling triggered by lymphotoxin β receptor

    Authors:
    Małgorzata Maksymowicz, Marta Miączyńska, Magdalena Banach-Orłowska
    Academic press:
    Cell Communication and Signaling (year: 2020, volume: 0,872222222222222, pages: 46043), Publisher: Springer Nature
    Status:
    Published
    DOI:
    10.1186/s12964-020-00664-0 – link to the publication
  2. Cholesterol restricts lymphotoxin β receptor-triggered NF-κB signaling

    Authors:
    Banach-Orłowska M, Wyszyńska R, Pyrzyńska B, Maksymowicz M, Gołąb J, Miączyńska M.
    Academic press:
    Cell Communication and Signaling (year: 2019, volume: 0,827083333333333, pages: 46041), Publisher: Springer Nature
    Status:
    Published
    DOI:
    10.1186/s12964-019-0460-1 – link to the publication
  3. The topology of lymphotoxin β receptor accumulated upon endolysosomal dysfunction dictates the NF-κB signaling outcome.

    Authors:
    Banach-Orłowska M, Jastrzębski K, Cendrowski J, Maksymowicz M, Wojciechowska K, Korostyński M, Moreau D, Gruenberg J, Miaczynska M.
    Academic press:
    Journal of Cell Science (year: 2018, volume: 131(22), pages: 46035), Publisher: The Company of Biologists
    Status:
    Published
    DOI:
    10.1242/jcs.218883 – link to the publication

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