New, multifunctional nanoparticles for combined photothermal and gene silencing cancer therapy

2016/21/B/ST8/00477

Keywords

Descriptors

  • ST5_10: Nanomateriały: nanocząstki, nanorurki
  • ST8_8: Inżynieria materiałowa (biomateriały, metale, ceramika, polimery, kompozyty)
  • ST5_21: Chemia polimerów

Panel

ST8 – Production and processes engineering: modelling, product design, process design and control, construction methods and engineering, power units and systems

Host institution

Uniwersytet im. Adama Mickiewicza w Poznaniu, Centrum Nanobiomedyczne

Voivodeship: wielkopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

prof. Stefan Jurga

Number of co-investigators in the project: 8

Call

OPUS 11 – announced on 2016-03-15

Amount awarded
1 523 316 PLN
Project start date
2017-04-13
Project end date
2021-10-12
Project duration
54 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Komputer. Cost: 6 000 PLN
  2. Lapotop.
  3. Laser. Cost: 25 000 PLN

Information in the final report

Publication in academic press/journals (6)

  1. Nano-mediated delivery of double-stranded RNA for gene therapy of glioblastoma multiforme

    Authors:
    Małgorzata Grabowska, Bartosz F Grześkowiak, Kosma Szutkowski, Darisz Wawrzynaika, Paweł Głodowicz, Jan Barciszewski, Stefan Jurga, Katarzyna Rolle, Radosław Mrówczyński
    Academic press:
    PLOS ONE (year: 2019, volume: -, pages: -), Publisher: Public Library of Science
    Status:
    Published
    DOI:
    10.1371/journal.pone.0213852 – link to the publication
  2. 1st Symposium on Polydopamine and NanoTech Poland 2018: Conference Report

    Authors:
    Radosław Mrówczyński, Marco d'Ischia, Haeshin Lee, Stefan Jurga
    Academic press:
    Biomimetics (year: 2018, volume: 3, pages: 37), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/biomimetics3040037 – link to the publication
  3. NDs@PDA@ICG Conjugates for Photothermal Therapy of Glioblastoma Multiforme

    Authors:
    Damian Maziukiewicz, Bartosz F. Grześkowiak, Emerson Coy, Stefan Jurga, Radosław Mrówczyński
    Academic press:
    Biomimetics (year: 2019, volume: 4, pages: 3), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/biomimetics4010003 – link to the publication
  4. Novel nanosystems to enhance biological activity of hydroxyapatite against dental caries

    Authors:
    Nataliya Babayevska, Marta Woźniak-Budych, Jagoda Litowczenko, Barbara Peplińska, Marcin Jarek, Patryk Florczak, Grażyna Bartkowiak, Beata Czarnecka, Stefan Jurga
    Academic press:
    Materials Science and Engineering: C (year: 2021, volume: 124, pages: 46037), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.msec.2021.112062 – link to the publication
  5. Surface functionalization – The way for advanced applications of smart materials

    Authors:
    Karolina Wieszczycka, KatarzynaStaszak, Marta J. Woźniak-Budych, Jagoda Litowczenko, Barbara M. Maciejewska, Stefan Jurga
    Academic press:
    Coordination Chemistry Reviews (year: 2021, volume: 436, pages: 46044), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ccr.2021.213846 – link to the publication
  6. Upconverting SrF2 nanoparticles doped with Yb3+/Ho3+, Yb3+/Er3+ and Yb3+/Tm3+ ions – optimisation of synthesis method, structural, spectroscopic and cytotoxicity studies

    Authors:
    Dominika przybylska, Anna ekner-Grzyb, Bartosz F. Grześkowiak, Tomasz Grzyb
    Academic press:
    Scientific Reports (year: 2019, volume: 9, pages: 8669), Publisher: Nature Publishing
    Status:
    Published
    DOI:
    10.1038/s41598-019-45025-1 – link to the publication

Book publications / chapters in book publications (1)

  1. Magnetic nanoparticles as a carrier of dsRNA for gene therapy

    Authors:
    Małgorzata Grabowska, Bartosz F. Grześkowiak, Katarzyna Rolle, Radosław Mrówczyński
    Book:
    Bio-Vectros , Methods in Molecular Biology (year: 2021, volume: 2211, pages: 69-81), Publisher: Springer
    Status:
    Published

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Graphic design and implementation: Jakub Piotrowski