Isotiocyanates as bioactive compounds counteracting virulent Escherichia coli infections

2016/21/B/NZ7/02077

Keywords

Descriptors

  • NZ7_1: Epidemiologia
  • NZ7_12: Prewencja chorób człowieka
  • NZ7_16: Inne zagadnienia pokrewne

Panel

NZ7 – Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution

Uniwersytet Gdański, Wydział Biologii

Voivodeship: pomorskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

prof. Agnieszka Monika Szalewska-Pałasz

Number of co-investigators in the project: 5

Call

OPUS 11 – announced on 2016-03-15

Amount awarded
1 274 800 PLN
Project start date
2017-01-24
Project end date
2023-01-23
Project duration
72 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. inkubator CO2. Cost: 35 000 PLN
  2. komora laminarna. Cost: 40 000 PLN
  3. termomikser. Cost: 15 000 PLN
  4. wirówka.
  5. wytrząsarka. Cost: 20 000 PLN

Information in the final report

Publication in academic press/journals (4)

  1. Dietary Isothiocyanates, Sulforaphane and 2-Phenethyl Isothiocyanate, Effectively Impair Vibrio cholerae Virulence

    Authors:
    Krause K, Pyrczak-Felczykowska A, Karczewska M, Narajczyk M, Herman-Antosiewicz A, Szalewska-Pałasz A, Nowicki D.
    Academic press:
    International Journal of Molecular Sciences (year: 2021, volume: 22(19), pages: 10187), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms221910187 – link to the publication
  2. Increased Levels of (p)ppGpp Correlate with Virulence and Biofilm Formation, but Not with Growth, in Strains of Uropathogenic Escherichia coli

    Authors:
    Karczewska M, Strzelecki P, Bogucka K, Potrykus K, Szalewska-Pałasz A, Nowicki D.
    Academic press:
    International Journal of Molecular Sciences (year: 2023, volume: 24(4), pages: 3315), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms24043315 – link to the publication
  3. Evaluation of the Anti-Shigellosis Activity of Dietary Isothiocyanates in Galleria mellonella Larvae

    Authors:
    Nowicki D, Krause K, Karczewska M, Szalewska-Pałasz A.
    Academic press:
    Nutrients (year: 2021, volume: 13(11), pages: 3967), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/nu13113967 – link to the publication
  4. Induction of the Stringent Response Underlies the Antimicrobial Action of Aliphatic Isothiocyanates

    Authors:
    Nowicki D, Krause K, Szamborska P, Żukowska A, Cech GM, Szalewska-Pałasz A.
    Academic press:
    Frontiers in Microbiology (year: 2021, volume: 11, pages: 591802), Publisher: Frontiers
    Status:
    Published
    DOI:
    10.3389/fmicb.2020.591802 – link to the publication

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Graphic design and implementation: Jakub Piotrowski