Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Isotiocyanates as bioactive compounds counteracting virulent Escherichia coli infections

2016/21/B/NZ7/02077

Keywords:

isothiocyanates pathogenic Escherichia coli Shiga toxin

Descriptors:

  • NZ7_1: Epidemiology
  • NZ7_12: Prevention of human diseases
  • NZ7_16: Other related subjects

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet Gdański, Wydział Biologii

woj. pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Agnieszka Szalewska-Pałasz 

Number of co-investigators in the project: 5

Call: OPUS 11 - announced on 2016-03-15

Amount awarded: 1 274 800 PLN

Project start date (Y-m-d): 2017-01-24

Project end date (Y-m-d): 2023-01-23

Project duration:: 72 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. inkubator CO2 (35 000 PLN)
  2. wirówka.
  3. wytrząsarka (20 000 PLN)
  4. komora laminarna (40 000 PLN)
  5. termomikser (15 000 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  1. Dietary Isothiocyanates, Sulforaphane and 2-Phenethyl Isothiocyanate, Effectively Impair Vibrio cholerae Virulence
    Authors:
    Krause K, Pyrczak-Felczykowska A, Karczewska M, Narajczyk M, Herman-Antosiewicz A, Szalewska-Pałasz A, Nowicki D.
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 22(19), strony: 10187), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms221910187 - link to the publication
  2. Evaluation of the Anti-Shigellosis Activity of Dietary Isothiocyanates in Galleria mellonella Larvae
    Authors:
    Nowicki D, Krause K, Karczewska M, Szalewska-Pałasz A.
    Academic press:
    Nutrients (rok: 2021, tom: 13(11), strony: 3967), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/nu13113967 - link to the publication
  3. Increased Levels of (p)ppGpp Correlate with Virulence and Biofilm Formation, but Not with Growth, in Strains of Uropathogenic Escherichia coli
    Authors:
    Karczewska M, Strzelecki P, Bogucka K, Potrykus K, Szalewska-Pałasz A, Nowicki D.
    Academic press:
    International Journal of Molecular Sciences (rok: 2023, tom: 24(4), strony: 3315), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms24043315 - link to the publication
  4. Induction of the Stringent Response Underlies the Antimicrobial Action of Aliphatic Isothiocyanates
    Authors:
    Nowicki D, Krause K, Szamborska P, Żukowska A, Cech GM, Szalewska-Pałasz A.
    Academic press:
    Frontiers in Microbiology (rok: 2021, tom: 11, strony: 591802), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fmicb.2020.591802 - link to the publication

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