Projects funded by the NCN
Function of autophagy in neuroblastoma cell death evoked by GD2 ganglioside-recognizing monoclonal antibodies.
2015/19/N/NZ1/00580
Keywords:
neuroblastoma gangliozyd GD2 autofagia PHLDA1 immunotherapy
Descriptors:
- NZ1_1: Molecular biology
- NZ1_2: Biochemistry
- NZ1_5: Genetic engineering
Panel:
NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology
Host institution :
Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii
woj. małopolskie
Principal investigator (from the host institution):
Number of co-investigators in the project: 2
Call: PRELUDIUM 10 - announced on 2015-09-15
Amount awarded: 99 600 PLN
Project start date (Y-m-d): 2016-06-23
Project end date (Y-m-d): 2018-06-22
Project duration:: 24 months (the same as in the proposal)
Project status: Project settled
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Publication in academic press/journals (1)
- GD2 ganglioside-binding antibody 14G2a and specific aurora A kinase inhibitor MK-5108 induce autophagy in IMR-32 neuroblastoma cellsAuthors:Małgorzata Durbas, Paweł Pabisz, Katarzyna Wawak, Aneta Wiśniewska, Elżbieta Boratyn, Iwona Nowak, Irena Horwacik, Olga Woźnicka, Hanna RokitaAcademic press:Apoptosis (rok: 2018, tom: 23(9-10), strony: 492-511), Wydawca: SpringerStatus:PublishedDOI:10.1007/s10495-018-1472-9 - link to the publication