Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Metabolic profiles, epidemiologic data and advanced bioinformatic tools in a holistic approach for the classification of healthy individuals and patients with different stages of clear cell renal cell carcinoma

2015/19/N/NZ7/03397

Keywords:

clear cell renal cell carcinoma metabolomics bioinformatics mass spectrometry analytical chemistry

Descriptors:

  • NZ2_4: Metabolomics
  • NZ2_7: Bioinformatics
  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

woj. pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Marta Kordalewska 

Number of co-investigators in the project: 2

Call: PRELUDIUM 10 - announced on 2015-09-15

Amount awarded: 148 500 PLN

Project start date (Y-m-d): 2016-09-05

Project end date (Y-m-d): 2021-03-04

Project duration:: 54 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. komputer osobisty (4 500 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  • Articles in post-conference publications (3)
  • Book publications / chapters in book publications (1)
  1. Design of Experiments in metabolomics-related studies: An overview
    Authors:
    Julia Jacyna, Marta Kordalewska,Michał Jan Markuszewski
    Academic press:
    Journal of Pharmaceutical and Biomedical Analysis (rok: 2019, tom: 164, strony: 598-606), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jpba.2018.11.027 - link to the publication
  2. Molecular signature of renal cell carcinoma by means of a multiplatform metabolomics analysis
    Authors:
    Marta Kordalewska, Renata Wawrzyniak , Julia Jacyna , Joanna Godzien, Angeles Lopez Gonzalves , Joanna Raczak-Gutknecht, Marcin Markuszewski, Piotr Gutknecht, Marcin Matuszewski, Janusz Siebert, Coral Barbas, Michał J. Markuszewski
    Academic press:
    Biochemistry and Biophysics Reports (rok: 2022, tom: 31, strony: 101318), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbrep.2022.101318 - link to the publication
  3. Evaluation of robustness in untargeted metabolomics: Application of multivariate analysis, linear regression and hierarchical modeling
    Authors:
    Julia Jacyna, Marta Kordalewska, Paweł Wiczling, Michał Jan Markuszewski
    Academic press:
    Journal of Chromatography Open (rok: 2022, tom: 2, strony: 100035), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jcoa.2022.100035 - link to the publication
  4. Comprehensive metabolic signature of renal dysplasia in children. A multiplatform metabolomics concept
    Authors:
    Szymon Macioszek , Renata Wawrzyniak , Anna Kranz, Marta Kordalewska, Wiktoria Struck-Lewicka, Danuta Dudzik, Margot Biesemans , Michał Maternik , Aleksandra M. Żurowska, Michał J. Markuszewski
    Academic press:
    Frontiers in Molecular Biosciences (rok: 2021, tom: 8, strony: 665661), Wydawca: Frontiers Inc
    Status:
    Published
    DOI:
    10.3389/fmolb.2021.665661 - link to the publication
  1. LC-MS and GC-MS-based metabolic fingerprinting reveals similarities in urine metabolic profiles in different urinary tract cancers
    Authors:
    Marta Kordalewska, Julia Jacyna, Renata Wawrzyniak, Marcin Markuszewski, Marcin Matuszewski, Roman Kaliszan, Michał J. Markuszewski
    Conference:
    Metabolomics Circle 2017 (rok: 2017, ), Wydawca: Medical Research Journal
    Data:
    konferencja 2017.11.17-18
    Status:
    Published
    DOI:
    link to the publication
  2. Alterations in biochemical pathways potentially related to renal cell carcinoma
    Authors:
    Marta Kordalewska, Renata Wawrzyniak, Joanna Godzień, Julia Jacyna, Joanna Raczak-Gutknecht, Angeles Lopez Gonzalves, Marcin Markuszewski, Marcin Matuszewski, Coral Barbas, Michał J. Markuszewski
    Conference:
    The 42nd Symposium on Chromatographic Methods of Investigating Organic Compounds (rok: 2019, ), Wydawca: Organizator konferencji
    Data:
    konferencja 2019.06.04-07
    Status:
    Published
    DOI:
    link to the publication
  3. What can we learn about differences in metabolic profiles of urinary tract cancers? Multiplatform approach
    Authors:
    Marta Kordalewska, Julia Jacyna, Renata Wawrzyniak, Marcin Markuszewski, Marcin Matuszewski, Michał J. Markuszewski
    Conference:
    Metabolomics 2019 (rok: 2019, ), Wydawca: Organizator konferencji
    Data:
    konferencja 2019.06.23-27
    Status:
    Published
    DOI:
    link to the publication
  1. Quality by Design in bioanalytics
    Authors:
    Julia Jacyna, Marta Kordalewska, Michał J. Markuszewski
    Book:
    Handbook of Bioanalytics (rok: 2021, tom: 1, strony: 45304), Wydawca: Springer
    Status:
    Published
    DOI:
    link to the publication

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