Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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The evaluation of electroporation and electrochemotherapy activity in human cancer cells sensitive and resistant to chemotherapy - in vitro study

2015/19/N/NZ7/01105

Keywords:

electropermeabilization multidrug-resistance human breast cancer cells

Descriptors:

  • NZ7_12: Prevention of human diseases

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Lekarski

woj. dolnośląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Nina Rembiałkowska 

Number of co-investigators in the project: 3

Call: PRELUDIUM 10 - announced on 2015-09-15

Amount awarded: 99 996 PLN

Project start date (Y-m-d): 2016-09-29

Project end date (Y-m-d): 2019-09-28

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (1)
  • Articles in post-conference publications (10)
  1. Doxorubicin Assisted by Microsecond Electroporation Promotes Irreparable Morphological Alternations in Sensitive and Resistant Human Breast Adenocarcinoma Cells
    Authors:
    Nina Rembiałkowska, Magda Dubińska-Magiera, Andrzej Sikora, Wojciech Szlasa, Anna Szewczyk, Hanna Czapor-Irzabek, Małgorzata Daczewska, Jolanta Saczko, Julita Kulbacka
    Academic press:
    Applied Sciences (rok: 2020, tom: 10, strony: 45309), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/app10082765 - link to the publication
  1. Cytotoxic potential of extract of Moringa Oleifera in human breast cancer cells
    Authors:
    Paulina Młynarczykowska, Nina Rembiałkowska
    Conference:
    3rd Wroclaw Scientific Meetings. Wrocław (rok: 2019, ), Wydawca: Wydawnictwo Naukowe TYGIEL
    Data:
    konferencja 1st-2nd March 2019
    Status:
    Published
  2. The diverse sensitivity of parental and resistant breast cancer cells after electrochemotherapeutic
    Authors:
    Nina Rembiałkowska, Anna Choromańska, M. Dubińska-Magiera, J. Rossowska, M. Kotulska, Jolanta Saczko, L.M. Mir, Julita Kulbacka
    Conference:
    19th IUPAB and 11th EBSA Congress. (rok: 2017, ), Wydawca: Eur.Biophys.J.
    Data:
    konferencja 16-20 July, 2017
    Status:
    Published
  3. Different electrochemotherapeutical sensitivity of human adenocarcinoma cell lines - an in vitro study
    Authors:
    Nina Rembiałkowska, Julita Kulbacka, Anna Choromańska, Magda Dubińska-Magiera, Jolanta Saczko.
    Conference:
    XXIV International Symposium on Bioelectrochemistry and Bioenergetics of the Bioelectrochemical Society. (rok: 2017, ), Wydawca: XXIV International Symposium on Bioelectrochemistry and Bioenergetics of the Bioelectrochemical Society
    Data:
    konferencja 3-7 July 2017
    Status:
    Published
  4. Ocena skuteczności elektrochemioterapii w warunkach in vitro
    Authors:
    Nina Rembiałkowska, Julita Kulbacka, Jolanta Saczko
    Conference:
    I Wrocławskie Spotkania Naukowe (rok: 2017, ), Wydawca: Wydawnictwo Naukowe Tygiel
    Data:
    konferencja 3 marca 2017
    Status:
    Published
  5. Zmiana ekspresji białka P-GP po zastosowaniu ECT
    Authors:
    Nina Rembiałkowska, Marta Harasiewicz, Zofia Marchewka, Julita Kulbacka, Jolanta Saczko
    Conference:
    I Wrocławskie Spotkania Naukowe. (rok: 2017, ), Wydawca: Wydawnictwo Naukowe TYGIEL
    Data:
    konferencja 3 marca 2017
    Status:
    Published
  6. Cytotoxic potential of extract of Moringa Oleifera and cell membrane permeabilization in human breast cancer cells in vitro
    Authors:
    Nina Rembiałkowska, Julita Kulbacka, Paulina Młynarczykowska, Jolanta Saczko
    Conference:
    3rd World Congress on Electroporation and Pulsed Electric Fields in Biology, Medicine and Food & Environmental Technologies incorporating The 16th International Bioelectronics Symposium Bioelectronics 2019 and The Bio & Food Electrotechnologies (BFE) (rok: 2019, ), Wydawca: International Society for Electroporation-Based Technologies and Treatments (ISEBTT)
    Data:
    konferencja 3-6 September, 2019
    Status:
    Published
  7. Electrochemotheraputic approach in human breast cancer cells with drug resistance
    Authors:
    Nina Rembiałkowska, Jolanta Saczko, Julita Kulbacka
    Conference:
    3rd Wroclaw Scientific Meetings. Wrocław (rok: 2019, ), Wydawca: Wydawnictwo Naukowe TYGIEL
    Data:
    konferencja 1st-2nd March 2019
    Status:
    Published
  8. Electroporation an effective tool to modulate drug resistance in human breast adenocarcinoma - in vitro study
    Authors:
    Nina Rembiałkowska, Julita Kulbacka, Anna Choromańska, Anna Szewczyk, Jolanta Saczko
    Conference:
    3rd World Congress on Electroporation and Pulsed Electric Fields in Biology, Medicine and Food & Environmental Technologies incorporating The 16th International Bioelectronics Symposium Bioelectronics 2019 and The Bio & Food Electrotechnologies (BFE) (rok: 2019, ), Wydawca: International Society for Electroporation-Based Technologies and Treatments (ISEBTT)
    Data:
    konferencja 3-6 September, 2019
    Status:
    Published
  9. Ocena wpływu chemioterapii wspomaganej elektroporacją na zmianę ekspresji białek oporności wielolekowej ludzkiego gruczolakoraka gruczołu sutkowego - badania in vitro
    Authors:
    Nina Rembiałkowska, Julita Kulbacka, Anna Choromańska, Katarzyna Bieżuńska-Kusiak, Jolanta Saczko
    Conference:
    Wpływ młodych naukowców na osiągnięcia polskiej nauki - X edycja. (rok: 2016, ), Wydawca: Creativetime
    Data:
    konferencja 10.12.2016
    Status:
    Published
  10. The mitochondrial response of cells after electroporation in medium of high- and low- conductivity
    Authors:
    Nina Rembiałkowska, Julita Kulbacka, Anna Choromańska, Katarzyna Bieżuńska-Kusiak, Jolanta Saczko
    Conference:
    2nd Wroclaw Scientific Meetings (rok: 2018, ), Wydawca: Wydawnictwo Naukowe TYGIEL
    Data:
    konferencja 2 marca 2018
    Status:
    Published

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