Estimation of antitumor activity of chemoimmunotherapy with nanoconjugates of methotrexate and vaccines based on dendritic cells with silenced IL-10 receptor expression

2015/19/N/NZ6/02908

Keywords

Descriptors

  • NZ6_8: Inne zagadnienia pokrewne
  • NZ5_8: Leczenie chorób zwierząt
  • NZ6_1: Odporność swoista i nieswoista

Panel

NZ6 – Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

Voivodeship: dolnośląskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

Agnieszka Anna Szczygieł

Number of co-investigators in the project: 3

Call

PRELUDIUM 10 – announced on 2015-09-15

Amount awarded
150 000 PLN
Project start date
2016-06-17
Project end date
2021-06-16
Project duration
60 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Oprogramowanie GraphPadPrism 6. Cost: 2 400 PLN
  2. Oprogramowanie GraphPadPrism 8 - roczna licencja.

Information in the final report

Publication in academic press/journals (2)

  1. Między biologią a medycyną: perspektywy wykorzystania komórek dendrytycznych w terapii przeciwnowotworowej

    Authors:
    Agnieszka Szczygieł, Elżbieta Pajtasz-Piasecka
    Academic press:
    Postępy Higieny i Medycyny Doświadczalnej (year: 2017, volume: 71, pages: 921-941), Publisher: Index Copernicus International
    Status:
    Published
    DOI:
    10.5604/01.3001.0010.5808 – link to the publication
  2. Immunomodulatory potential of anticancer therapy composed of methotrexate nanoconjugate and dendritic cell‑based vaccines in murine colon carcinoma

    Authors:
    Agnieszka Szczygieł; Natalia Anger‑Góra; Katarzyna Węgierek‑Ciura; Jagoda Mierzejewska; Joanna Rossowska; Tomasz M. Goszczyński; Marta Świtalska; Elżbieta Pajtasz‑Piasecka
    Academic press:
    Oncology Reports (year: 2021, volume: 45, pages: 945-962), Publisher: Spandidos Publications LTD
    Status:
    Published
    DOI:
    10.3892/or.2021.7930 – link to the publication

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