Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Estimation of antitumor activity of chemoimmunotherapy with nanoconjugates of methotrexate and vaccines based on dendritic cells with silenced IL-10 receptor expression

2015/19/N/NZ6/02908

Keywords:

chemoimmunotherapy nanoconjugates methotrexate dendritic cell-based cellular vaccines IL-10 receptor IL-10R

Descriptors:

  • NZ6_8: Other related subjects
  • NZ5_8: Animal disease treatment
  • NZ6_1: Adaptive and innate immunity

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

woj. dolnośląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Agnieszka Szczygieł 

Number of co-investigators in the project: 3

Call: PRELUDIUM 10 - announced on 2015-09-15

Amount awarded: 150 000 PLN

Project start date (Y-m-d): 2016-06-17

Project end date (Y-m-d): 2021-06-16

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Oprogramowanie GraphPadPrism 6 (2 400 PLN)
  2. Oprogramowanie GraphPadPrism 8 - roczna licencja.

Information in the final report

  • Publication in academic press/journals (2)
  1. Immunomodulatory potential of anticancer therapy composed of methotrexate nanoconjugate and dendritic cell‑based vaccines in murine colon carcinoma
    Authors:
    Agnieszka Szczygieł; Natalia Anger‑Góra; Katarzyna Węgierek‑Ciura; Jagoda Mierzejewska; Joanna Rossowska; Tomasz M. Goszczyński; Marta Świtalska; Elżbieta Pajtasz‑Piasecka
    Academic press:
    Oncology Reports (rok: 2021, tom: 45, strony: 945-962), Wydawca: Spandidos Publications LTD
    Status:
    Published
    DOI:
    10.3892/or.2021.7930 - link to the publication
  2. Między biologią a medycyną: perspektywy wykorzystania komórek dendrytycznych w terapii przeciwnowotworowej
    Authors:
    Agnieszka Szczygieł, Elżbieta Pajtasz-Piasecka
    Academic press:
    Postępy Higieny i Medycyny Doświadczalnej (rok: 2017, tom: 71, strony: 921-941), Wydawca: Index Copernicus International
    Status:
    Published
    DOI:
    10.5808 - link to the publication

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