Sperm quality control by PXT1-BAG6 protein interaction.

2015/19/B/NZ4/00576

Keywords

Descriptors

  • NZ4_2: Fizjologia
  • NZ4_11: Metabolizm

Panel

NZ4 – Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution

Uniwersytet Jagielloński, Wydział Biologii

Voivodeship: małopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr hab. Paweł Grzmil

Number of co-investigators in the project: 5

Call

OPUS 10 – announced on 2015-09-15

Amount awarded
463 000 PLN
Project start date
2016-07-13
Project end date
2021-01-12
Project duration
54 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Czytnik płytek z opcją czytania luminescencji. Cost: 50 000 PLN
  2. Komputer Dell Vostro3650MT.
  3. Wirówka laboratoryjna (2 pcs). Cost: 12 000 PLN
  4. Zestaw pipet autoamtycznych (2 pcs). Cost: 4 400 PLN

Information in the final report

Publication in academic press/journals (2)

  1. Mouse Pxt1 expression is regulated by Mir6996 miRNA

    Authors:
    Igor Tomczyk, Mikołaj Rokicki, Wioleta Sieńko, Katarzyna Rożek, Anna Nalepa, Jasmin Wiench, Paweł Grzmil
    Academic press:
    Theriogenology (year: 2023, volume: 210, pages: 46281), Publisher: ELSEVIER
    Status:
    Published
    DOI:
    10.1016/j.theriogenology.2023.07.010 – link to the publication
  2. Increased DNA strand breaks in spermatozoa of Pxt1 knockout mice

    Authors:
    Bernadetta Pawlicka, Michał Duliban, Mateusz Zięba, Michał Bochenek, Kamila Zięba, Ibrahim Adham, Maja Studencka-Turski, Andreas Meinhardt, Paweł Grzmil
    Academic press:
    Reproduction, Fertility and Development (year: 2023, volume: 35(11), pages: 589-600), Publisher: CSIRO Publishing
    Status:
    Published
    DOI:
    10.1071/RD23061 – link to the publication

Articles in post-conference publications (2)

  1. MiRNA regulates the activity of Pxt1 gene

    Authors:
    IGOR TOMCZYK, BERNADETTA PAWLICKA, JASMIN WIENCH, KARINA KACZMAREK, PAWEŁ GRZMIL
    Conference:
    XXIX International Symposium Molecular and Physiological Aspects of Regulatory Processes in the Organism (year: 2022, pages: 55), Publisher: Biological Commission of the Polish Academy of Science - Cracow Branch
    Date:
    conference 2022-10-8-9
    Status:
    Published
  2. PXT1 And BAG6 interplay in the control of sperm quality in mouse

    Authors:
    Igor Tomczyk, Bernadeta Pawlicka, Katarzyna Rożek, Agneta Auer, Paweł Grzmil
    Conference:
    XXVIII International Symposium Molecular and Physiological Aspects of Regulatory Processes in the Organism (year: 2021, pages: 56), Publisher: Biological Commission of the Polish Academy of Sciences – Cracow Branch
    Date:
    conference 44457
    Status:
    Published

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