Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Sperm quality control by PXT1-BAG6 protein interaction.

2015/19/B/NZ4/00576

Keywords:

spermatogenesis apoptosis knockout sperm quality fertility

Descriptors:

  • NZ4_2: Physiology
  • NZ4_11: Metabolism

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Uniwersytet Jagielloński, Wydział Biologii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Paweł Grzmil 

Number of co-investigators in the project: 5

Call: OPUS 10 - announced on 2015-09-15

Amount awarded: 463 000 PLN

Project start date (Y-m-d): 2016-07-13

Project end date (Y-m-d): 2021-01-12

Project duration:: 54 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Zestaw pipet autoamtycznych (2 szt.) (4 400 PLN)
  2. Komputer Dell Vostro3650MT.
  3. Czytnik płytek z opcją czytania luminescencji (50 000 PLN)
  4. Wirówka laboratoryjna (2 szt.) (12 000 PLN)

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (2)
  1. Mouse Pxt1 expression is regulated by Mir6996 miRNA
    Authors:
    Igor Tomczyk, Mikołaj Rokicki, Wioleta Sieńko, Katarzyna Rożek, Anna Nalepa, Jasmin Wiench, Paweł Grzmil
    Academic press:
    Theriogenology (rok: 2023, tom: 210, strony: 45551), Wydawca: ELSEVIER
    Status:
    Published
    DOI:
    10.1016/j.theriogenology.2023.07.010 - link to the publication
  2. Increased DNA strand breaks in spermatozoa of Pxt1 knockout mice
    Authors:
    Bernadetta Pawlicka, Michał Duliban, Mateusz Zięba, Michał Bochenek, Kamila Zięba, Ibrahim Adham, Maja Studencka-Turski, Andreas Meinhardt, Paweł Grzmil
    Academic press:
    Reproduction, Fertility and Development (rok: 2023, tom: 35(11), strony: 589-600), Wydawca: CSIRO Publishing
    Status:
    Published
    DOI:
    10.1071/RD23061 - link to the publication
  1. MiRNA regulates the activity of Pxt1 gene
    Authors:
    IGOR TOMCZYK, BERNADETTA PAWLICKA, JASMIN WIENCH, KARINA KACZMAREK, PAWEŁ GRZMIL
    Conference:
    XXIX International Symposium Molecular and Physiological Aspects of Regulatory Processes in the Organism (rok: 2022, ), Wydawca: Biological Commission of the Polish Academy of Science - Cracow Branch
    Data:
    konferencja 2022-10-8-9
    Status:
    Published
  2. PXT1 And BAG6 interplay in the control of sperm quality in mouse
    Authors:
    Igor Tomczyk, Bernadeta Pawlicka, Katarzyna Rożek, Agneta Auer, Paweł Grzmil
    Conference:
    XXVIII International Symposium Molecular and Physiological Aspects of Regulatory Processes in the Organism (rok: 2021, ), Wydawca: Biological Commission of the Polish Academy of Sciences – Cracow Branch
    Data:
    konferencja 44457
    Status:
    Published

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