Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The role of NADPH oxidase Nox4 in vascular endothelial dysfunction caused by the effect of docetaxel

2015/19/N/NZ4/01061

Keywords:

endothelial dysfunction NADPH oxidase docetaxel

Descriptors:

  • NZ4_2: Physiology
  • NZ4_4: Pathophysiology
  • NZ4_12: Other related subjects

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum, Wydział Lekarski

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Piotr Szczepaniak 

Number of co-investigators in the project: 2

Call: PRELUDIUM 10 - announced on 2015-09-15

Amount awarded: 149 820 PLN

Project start date (Y-m-d): 2016-07-07

Project end date (Y-m-d): 2019-07-06

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (1)
  1. Breast cancer chemotherapy induces vascular dysfunction and hypertension through a NOX4-dependent mechanism
    Authors:
    Piotr Szczepaniak, Mateusz Siedlinski, Diana Hodorowicz-Zaniewska, Ryszard Nosalski, Tomasz P Mikolajczyk, Aneta M Dobosz, Anna Dikalova, Sergey Dikalov, Joanna Streb, Katarzyna Gara, Pawel Basta, Jaroslaw Krolczyk, Joanna Sulicka-Grodzicka, Ewelina Jozefczuk, Anna Dziewulska, Blessy Saju, Iwona Laksa, Wei Chen, John Dormer, Maciej Tomaszewski, Pasquale Maffia, Marta Czesnikiewicz-Guzik, Filippo Crea, Agnieszka Dobrzyn, Javid Moslehi, Tomasz Grodzicki, David G Harrison, Tomasz J Guzik
    Academic press:
    The Journal of Clinical Investigation (rok: 2022, tom: 132, strony: 45309), Wydawca: American Society for Clinical Investigation
    Status:
    Published
    DOI:
    10.1172/JCI149117 - link to the publication