Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Potential applications in medicine of norphthalocyanine and phthalocyanine conjugates with bicyclic sesquiterpenes

2015/19/N/NZ7/01342

Keywords:

phthalocyanine azulene singlet oxygen medicinal chemistry photocytotoxicity in vitro activity

Descriptors:

  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology
  • NZ6_4: Bacteriology
  • NZ7_16: Other related subjects

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Sebastian Lijewski 

Number of co-investigators in the project: 2

Call: PRELUDIUM 10 - announced on 2015-09-15

Amount awarded: 149 978 PLN

Project start date (Y-m-d): 2016-08-23

Project end date (Y-m-d): 2020-08-22

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Piecyk próżniowy do suszenia B-585 firmy BÜCHI (16 974 PLN)
  2. Pompa próżniowa V-100 z kontrolerem próżni I-100 firmy BÜCHI (12 644 PLN)

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (2)
  1. Photodynamic inactivation of Enterococcus faecalis by conjugates of zinc(II) phthalocyanines with thymol and carvacrol loaded into lipid vesicles
    Authors:
    Lukasz Sobotta, Sebastian Lijewski, Jolanta Dlugaszewska, Joanna Nowicka, Jadwiga Mielcarek, Tomasz Goslinski
    Academic press:
    Inorganica Chimica Acta (rok: 2019, tom: 489, strony: 180-190), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ica.2019.02.031 - link to the publication
  2. Derivatives of Azulene of Potential Applications in Medicine
    Authors:
    Paweł Bakun, Beata Czarczynska-Goslinska, Tomasz Goslinski, Sebastian Lijewski
    Academic press:
    Medicinal Chemistry Research (rok: 2020, ), Wydawca: Springer
    Status:
    Submitted
  1. TERPENE-PHTHALOCYANINE CONJUGATES AND THEIR PHOTODYNAMIC ACTIVITY AGAINST ENTEROCOCCUS FAECALIS
    Authors:
    Sebastian Lijewski, Lukasz Sobotta, Jolanta Dlugaszewska, Joanna Nowicka, Jadwiga Mielcarek,Tomasz Goslinski
    Conference:
    18th Blue Danube Symposium on Heterocyclic Chemistry (rok: 2019, ), Wydawca: Faculty of Chemistry and Chemical Technology, University of Ljubljana, Slovenia
    Data:
    konferencja 43726
    Status:
    Published
  2. OTRZYMYWANIE I CHARAKTERYSTYKA FIZYKOCHEMICZNA KONIUGATÓW MALEO - ORAZ FTALONITRYLOWYCH Z AZULENEM ORAZ GWAJAZULENEM ORAZ OCENA ICH REAKTYWNOŚCI W REAKCJACH CYKLOTETRAMERYZACJI
    Authors:
    Sebastian Lijewski, Tomasz Kolebski, Tomasz Gośliński
    Conference:
    I I Ogólnopolskie Sympozjum Chemii Bioorganicznej, Organicznej i Biomateriałów (rok: 2017, ), Wydawca: Politechnika Poznańska, Wydział Technologii Chemicznej
    Data:
    konferencja 2 grudnia
    Status:
    Published