Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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The influence of ectromelia (mousepox) virus on the activation of signaling components of the noncanonical NF-κB activation pathway - in vitro studies

2015/19/D/NZ6/02873

Keywords:

ectromelia virus noncanonical NF-κB activation pathway transcription factor

Descriptors:

  • NZ6_5: Virology
  • NZ6_1: Adaptive and innate immunity
  • NZ6_8: Other related subjects

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Szkoła Główna Gospodarstwa Wiejskiego w Warszawie, Instytut Medycyny Weterynaryjnej

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Justyna Struzik 

Number of co-investigators in the project: 5

Call: SONATA 10 - announced on 2015-09-15

Amount awarded: 500 000 PLN

Project start date (Y-m-d): 2016-07-22

Project end date (Y-m-d): 2020-07-21

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Dewar.
  2. ph-metr (7 500 PLN)
  3. Termowytrząsarka do płytek mikrotitracyjnych (7 200 PLN)
  4. Autoklaw laboratoryjny (7 500 PLN)
  5. Kołyska laboratoryjna (2 800 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  • Articles in post-conference publications (6)
  1. Manipulation of non-canonical NF-κB signaling by non-oncogenic viruses
    Authors:
    Justyna Struzik, Lidia Szulc-Dąbrowska
    Academic press:
    Archivum Immunologiae et Therapiae Experimentalis (rok: 2019, tom: 67, strony: 41-48), Wydawca: Springer International Publishing
    Status:
    Published
    DOI:
    10.1007/s00005-018-0522-x - link to the publication
  2. NF-κB Signaling in Targeting Tumor Cells by Oncolytic Viruses-Therapeutic Perspectives
    Authors:
    Justyna Struzik, Lidia Szulc-Dąbrowska
    Academic press:
    Cancers (Basel) (rok: 2018, tom: 10, strony: E426), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cancers10110426 - link to the publication
  3. NF-κB as an important factor in optimizing poxvirus-based vaccines against viral infections
    Authors:
    Justyna Struzik, Lidia Szulc-Dąbrowska
    Academic press:
    Pathogens (rok: 2020, tom: 9, strony: 1001), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/pathogens9121001 - link to the publication
  4. First insight into the modulation of noncanonical NF-κB signaling components by poxviruses in established immune-derived cell lines: an in vitro model of ectromelia virus infection
    Authors:
    Justyna Struzik, Lidia Szulc-Dąbrowska, Matylda B. Mielcarska, Magdalena Bossowska-Nowicka, Michał Koper, Małgorzata Gieryńska
    Academic press:
    Pathogens (rok: 2020, tom: 9, strony: 814), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/pathogens9100814 - link to the publication
  1. Manipulation of RelB nuclear translocation by ectromelia virus in RAW 264.7 murine macrophages
    Authors:
    Justyna Struzik, Lidia Szulc-Dąbrowska, Małgorzata Gieryńska
    Conference:
    XVIII Conference DIAGMOL 2017 "Molecular biology in diagnostics of infectious diseases and biotechnology" (rok: 2017, ), Wydawca: SGGW w Warszawie
    Data:
    konferencja 25 listopad
    Status:
    Published
  2. Interactions of nonconcogenic viruses with NF-kB inducing kinase
    Authors:
    Justyna Struzik, Lidia Szulc-Dąbrowska, Małgorzata Gieryńska
    Conference:
    XVII Conference DIAGMOL 2016 "Molecular biology in diagnostics of infectious diseases and biotechnology" (rok: 2016, ), Wydawca: SGGW w Warszawie
    Data:
    konferencja 5 listopad
    Status:
    Published
  3. The influence of ectromelia virus on tumor necrosis factorsuperfamily-induced non-canonical NF-κB signaling
    Authors:
    Justyna Struzik, Lidia Szulc-Dąbrowska, Małgorzata Gieryńska
    Conference:
    XIX Conference DIAGMOL 2018 "Molecular biology in diagnostics of infectious diseases and biotechnology" (rok: 2018, ), Wydawca: SGGW w Warszawie
    Data:
    konferencja 17 listopad
    Status:
    Published
  4. Ectromelia virus inhibits the activation of non-canonical NF-κB signaling in RAW 264.7 murine macrophages
    Authors:
    Justyna Struzik, Lidia Szulc-Dąbrowska, Małgorzata Gieryńska
    Conference:
    XIX Conference DIAGMOL 2019 "Molecular biology in diagnostics of infectious diseases and biotechnology" (rok: 2019, ), Wydawca: SGGW w Warszawie
    Data:
    konferencja 43792
    Status:
    Published
  5. Expression of the components of the non-canonical NF-κB signaling in RAW 264.7 murine macrophage cell line infected with ectromelia virus
    Authors:
    Justyna Struzik, Matylda Mielcarska, Magdalena Bossowska-Nowicka, Lidia Szulc-Dąbrowska, Małgorzata Gieryńska
    Conference:
    4th Congress of Baltic Microbiologists (CBM2018) (rok: 2018, ), Wydawca: Polskie Towarzystwo Biochemiczne
    Data:
    konferencja 10-12 wrzesień
    Status:
    Published
  6. Influence of ectromelia virus on the noncanonical NF-kB activation in JAWSII murine dendritic cell line
    Authors:
    Justyna Struzik, Lidia Szulc-Dąbrowska, Małgorzata Gieryńska
    Conference:
    7th International Weigl Conference (rok: 2017, ), Wydawca: Ukrainian Society of Cell Biology
    Data:
    konferencja 26-29 wrzesień
    Status:
    Published

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