Projects funded by the NCN
Do silent synapses regulate alcohol relapse?
2015/19/B/NZ4/03163
Keywords:
Arc protein silent synapse alcohol relapse AMPA receptors dentate gyrus
Descriptors:
- NZ4_7: Neurophysiology
- NZ4_9: Systems neurobiology
Panel:
NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology
Host institution :
Instytut Biologii Doświadczalnej im. M. Nenckiego Polskiej Akademii Nauk
woj. mazowieckie
Principal investigator (from the host institution):
Number of co-investigators in the project: 5
Call: OPUS 10 - announced on 2015-09-15
Amount awarded: 1 210 000 PLN
Project start date (Y-m-d): 2016-07-21
Project end date (Y-m-d): 2020-07-20
Project duration:: 48 months (the same as in the proposal)
Project status: Project settled
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Equipment purchased [PL]
- pompa perystaltyczna (8 000 PLN)
- waźnia wodna z kontrolerem temperatury (19 000 PLN)
- Leica wibratom 1200VT z VibroCheck (60 000 PLN)
- szybka kamera CCD z oprogramowaniem (28 000 PLN)
- wzmacniacz, np. Molecular Devices Multiclamo 700B (50 000 PLN)
- karta akwizycyjna (26 000 PLN)
- mikroskop prosty Zeiss z ptyką podczerwieni, DiC i epifluorescencją (100 000 PLN)
- platforma pomiarowa Alcatraz (platforma pomiarowa, dwa mikromanipulatory z kontrolerem, stolik pod mikroskop oraz komora pomiarowa podgrzewana) (90 000 PLN)
- stół antywibracyjny i klatka Faraday'a (50 000 PLN)
- komputer i 2 monitory wraz z oprogramowaniem do akwizycji danych elektrofizjologicznych (11 000 PLN)
Information in the final report
- Publication in academic press/journals (2)
- Personality driven alcohol and drug abuse: New mechanisms revealed.Authors:Skóra MN, Pattij T, Beroun A, Kogias G, Mielenz D, de Vries T, Radwanska K, Müller CP.Academic press:Neuroscience & Biobehavioral Reviews (rok: 2020, tom: 116, strony: 64-73), Wydawca: ElsevierStatus:PublishedDOI:1016/j.neubiorev.2020.06.023 - link to the publication
- Generation of silent synapses in dentate gyrus correlates with development of alcohol addiction.Authors:Beroun A, Nalberczak-Skóra M, Harda Z, Piechota M, Ziółkowska M, Cały A, Pagano R, Radwanska K.Academic press:Neuropsychopharmacology (rok: 2018, tom: 43(10), strony: 1989-1999.), Wydawca: NatureStatus:PublishedDOI:10.1038/s41386-018-0119-4 - link to the publication