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Information on the principal investigator and host institution

Information of the project and the call

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Antimicrobial photoinactivation as an effective tool for sensitization of multidrug resistant ESKAPE pathogenes to antimicrobials.

2015/19/B/NZ7/02487

Keywords:

Acinetobacter baumanii Enterobacter spp. Enterococcus spp. Klebsiella pneumoniae multidrugresistance photoinactivation Pseudomonas aeruginosa Staphylococcus aureus synergy

Descriptors:

  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

woj. pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Mariusz Grinholc 

Number of co-investigators in the project: 4

Call: OPUS 10 - announced on 2015-09-15

Amount awarded: 662 400 PLN

Project start date (Y-m-d): 2016-10-03

Project end date (Y-m-d): 2020-10-02

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (5)
  • Articles in post-conference publications (5)
  1. Antimicrobials Are a Photodynamic Inactivation Adjuvant for the Eradication of Extensively Drug-Resistant Acinetobacter baumannii.
    Authors:
    A. Wozniak, A. Rapacka-Zdonczyk, N.T. Mutters, M. Grinholc.
    Academic press:
    Frontiers in Microbiology (rok: 2019, tom: 10, strony: 229), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fmicb.2019.00229 - link to the publication
  2. Development of Staphylococcus aureus tolerance to antimicrobial photodynamic inactivation and antimicrobial blue light upon sub-lethal treatment.
    Authors:
    Rapacka-Zdonczyk A., Wozniak A., Pieranski M., Woziwodzka A., Bielawski K.P., Grinholc M.
    Academic press:
    Scientific Reports (rok: 2019, tom: 9(1), strony: 9423), Wydawca: Nature Publishing Group
    Status:
    Published
    DOI:
    10.1038/s41598-019-45962-x - link to the publication
  3. Combined antimicrobial activity of photodynamic inactivation and antimicrobials – state of the art.
    Authors:
    A. Wozniak, M. Grinholc
    Academic press:
    Frontiers in Microbiology (rok: 2018, tom: 9, strony: 930), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fmicb.2018.00930 - link to the publication
  4. Antimicrobial Blue Light Photoinactivation of Pseudomonas aeruginosa: Quorum Sensing Signaling Molecules, Biofilm Formation and Pathogenicity.
    Authors:
    Fila G., Krychowiak M., Rychlowski M., Bielawski K.P., Grinholc M.
    Academic press:
    Journal of Biophotonics (rok: 2018, tom: 11, strony: 45303), Wydawca: WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
    Status:
    Published
    DOI:
    10.1002/jbio.201800079 - link to the publication
  5. Antimicrobial Photodynamic Inactivation Affects the Antibiotic Susceptibility of Enterococcus spp. Clinical Isolates in Biofilm and Planktonic Cultures
    Authors:
    AgataWozniak, Beata Kruszewska, Michał Karol Pieranski, Michał Rychłowski, Mariusz Grinholc
    Academic press:
    Biomolecules (rok: 2021, tom: 11, strony: 693), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/biom11050693 - link to the publication
  1. MULTIPLE SUB-LETHAL ANTIMICROBIAL PHOTODYNAMIC INACTIVATION AND BLUE LIGHT TREATMENT OF S. AUREUS LEAD TO TOLERANCE DEVELOPMENT
    Authors:
    A. Rapacka-Zdonczyk, A. Wozniak., M. Grinholc
    Conference:
    Light&Life 18th Congress of the European Society for Photobiology (rok: 2019, ), Wydawca: MCI Spain Event Services
    Data:
    konferencja 25-30.08
    Status:
    Published
  2. PRESENCE OF ENDOGENOUS PORPHYRINS AND ANTIMICROBIAL BLUE LIGHT RENDERS ACINETOBACTER BAUMANNII CLINICAL ISOLATES SUSCEPTIBLE TO ANTIMICROBIALS
    Authors:
    A. Wozniak, A. Rapacka-Zdonczyk, P. CzaplewskaInter, M. Grinholc
    Conference:
    Light&Life 18th Congress of the European Society for Photobiology (rok: 2019, ), Wydawca: MCI Spain Event Services
    Data:
    konferencja 25-30.08
    Status:
    Published
  3. Blue light treatment – more than bactericidal activity
    Authors:
    Mariusz Grinholc, Grzegorz Fila, Tomasz Wasylew and Agata Wozniak
    Conference:
    16th International Photodynamic Therapy World Congress (rok: 2017, ), Wydawca: University of Coimbra
    Data:
    konferencja 8-13 czerwca
    Status:
    Published
  4. ANTIMICROBIAL PHOTODYNAMIC INACTIVATION AND ANTIMICROBIAL BLUE LIGHT: SUCCESSFUL ANTIBIOTIC ADJUVANT FOR THE ERADICATION OF EXTENSIVELY DRUG-RESISTANT PATHOGENS AND POSSIBLE TOLERANCE DEVELOPMENT.
    Authors:
    M. Grinholc, A. Wozniak, A. Rapacka-Zdonczyk
    Conference:
    Light&Life 18th Congress of the European Society for Photobiology (rok: 2019, ), Wydawca: MCI Spain Event Services
    Data:
    konferencja 25-30.08
    Status:
    Published
  5. Influence of blue light treatment on survival rate of ESKAPE pathogens
    Authors:
    Agata Woźniak, Mariusz Grinholc
    Conference:
    16th International Photodynamic Therapy World Congress (rok: 2017, ), Wydawca: University of Coimbra
    Data:
    konferencja 8-13 czerwca
    Status:
    Published

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