Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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An association between systemic inflammation and post-stroke depressive symptoms.

2015/19/B/NZ4/00287

Keywords:

inflammation cytokines stroke depression

Descriptors:

  • NZ4_4: Pathophysiology

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Lekarski

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Tomasz Dziedzic 

Number of co-investigators in the project: 8

Call: OPUS 10 - announced on 2015-09-15

Amount awarded: 1 191 720 PLN

Project start date (Y-m-d): 2016-07-07

Project end date (Y-m-d): 2021-07-06

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. BrainVoyager - oprogramowanie do analizy wyników fMRI (30 000 PLN)
  2. zamrażarka niskotemperaturowa (45 000 PLN)

Information in the final report

  • Publication in academic press/journals (8)
  1. Association of early and later depressive symptoms with functional outcome after ischemic stroke
    Authors:
    Lopatkiewicz AM, Pera J, Slowik A, Dziedzic T
    Academic press:
    Journal of Neural Transmission (rok: 2021, tom: 128, strony: 679-686), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s00702-021-02328-w - link to the publication
  2. Reduced ex vivo release of pro-inflammatory cytokines and elevated plasma interleukin-6 are inflammatory signatures of post-stroke delirium.
    Authors:
    Kowalska K, Klimiec E, Weglarczyk K, Pera J, Slowik A, Siedlar M, Dziedzic T
    Academic press:
    J Neuroinflammation (rok: 2018, tom: 15, strony: 111), Wydawca: BMC (part of Springer Nature)
    Status:
    Published
    DOI:
    10.1186/s12974-018-1156-y - link to the publication
  3. Ex vivo synthesized cytokines as a biomarker of stroke-associated pneumonia
    Authors:
    Gradek-Kwinta E, Czyzycki M, Weglarczyk K, Slowik A, Siedlar M, Dziedzic T
    Academic press:
    Clin Chim Acta (rok: 2020, tom: 510, strony: 260-263), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.cca.2020.07.035 - link to the publication
  4. Glucocorticoid Resistance is Associated with Poor Functional Outcome After Stroke
    Authors:
    Lopatkiewicz AM, Gradek-Kwinta E, Czyzycki M, Pera J, Slowik A, Dziedzic T
    Academic press:
    Cell Mol Neurobiol (rok: 2020, tom: 40, strony: 1321-1326), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1007/s10571-020-00818-1 - link to the publication
  5. The specific ex vivo released cytokine profile is associated with ischemic stroke outcome and improves its prediction
    Authors:
    Klimiec-Moskal E, Piechota M, Pera J, Weglarczyk K, Slowik A, Siedlar M, Dziedzic T
    Academic press:
    J Neuroinflammation (rok: 2020, tom: 17, strony: 7), Wydawca: BMC (part of Springer Nature)
    Status:
    Published
    DOI:
    10.1186/s12974-019-1691-1 - link to the publication
  6. C-reactive protein and post-stroke depressive symptoms.
    Authors:
    Kowalska K, Pasinska P, Klimiec-Moskal E, Pera J, Slowik A, Klimkowicz-Mrowiec A, Dziedzic T
    Academic press:
    Sci Rep (rok: 2020, tom: 10, strony: 1431), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1038/s41598-020-58478-6 - link to the publication
  7. Early apathetic, but not depressive, symptoms are associated with poor outcome after stroke
    Authors:
    Lopatkiewicz AM, Pera J, Slowik A, Dziedzic T
    Academic press:
    European Journal of Neurology (rok: 2021, tom: 28, strony: 1949-1957), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1111/ene.14785 - link to the publication
  8. Toll-like receptor 4-mediated cytokine synthesis and post-stroke depressive symptoms.
    Authors:
    Korostynski M, Hoinkis D, Piechota M, Golda S, Pera J, Slowik A, Dziedzic T.
    Academic press:
    Translational Psychiatry (rok: 2021, tom: 11, strony: 246), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1038/s41398-021-01359-x. - link to the publication

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