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Factors affecting the transfer of leptin through blood-brain barrier (BBB) and the phenomenon of leptin resistance.

2015/19/B/NZ9/01314

Keywords:

leptin resistance blood-brain barrier leptin photoperiod metabolism

Descriptors:

  • NZ9_2: Animal production
  • NZ9_13: Other related subjects

Panel:

NZ9 - Fundamentals of applied life sciences and biotechnology: agricultural, forestry, horticulture, animal production and fishery, food and nutrition sciences, industrial biosciences, environmental biotechnology and remediation

Host institution :

Uniwersytet Rolniczy im. Hugona Kołłątaja w Krakowie, Wydział Hodowli i Biologii Zwierząt

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Dorota Zięba-Przybylska 

Number of co-investigators in the project: 8

Call: OPUS 10 - announced on 2015-09-15

Amount awarded: 827 737 PLN

Project start date (Y-m-d): 2016-06-20

Project end date (Y-m-d): 2019-12-19

Project duration:: 42 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (6)
  • Articles in post-conference publications (6)
  1. Resistin Regulates Reproductive Hormone Secretion from the Ovine Adenohypophysis Depending on Season
    Authors:
    W. Biernat, K. Kirsz, M. Szczesna, D.A. Zieba
    Academic press:
    Domestic Animal Endocrinology (rok: 2018, tom: 65, strony: 95-100), Wydawca: ELSEVIER
    Status:
    Published
    DOI:
    10.1016/j.domaniend.2018.07.001 - link to the publication
  2. Changes in expression of the genes for the leptin signaling in hypothalamic-pituitary selected areas and endocrine responses to long-term manipulation in body weight and resistin in ewes.
    Authors:
    Zieba D.A., Biernat W., Szczesna M., Kirsz K., Barć J, Misztal T.
    Academic press:
    International Journal of Molecular Sciences (rok: 2020, tom: 21, strony: 4238), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms21124238 - link to the publication
  3. Factors Affecting the Transfer of Leptin Through Blood-Brain Barrier (BBB). The Implication for Leptin Resistance
    Authors:
    D.A. Zięba
    Academic press:
    Approaches in Poultry, Dairy & Veterinary Sciences (rok: 2019, tom: 6 (5), strony: 595-598), Wydawca: Crimson Publishers
    Status:
    Published
    DOI:
    10.31031/APDV.2019.06.000648 - link to the publication
  4. Hypothalamic–Pituitary and Adipose Tissue Responses to the Effect of Resistin in Sheep: The Integration of Leptin and Resistin Signaling Involving a Suppressor of Cytokine Signaling 3 and the Long Form of the Leptin Receptor
    Authors:
    D.A. Zięba, W. Biernat, M. Szczesna, K. Kirsz, T. Misztal
    Academic press:
    Nutrients (rok: 2019, tom: 11, strony: 2180), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/nu11092180 - link to the publication
  5. Roles of Leptin and Resistin in Metabolism, Reproduction and Leptin Resistance.
    Authors:
    Zieba D.A., Biernat. W., Barć J.
    Academic press:
    Domestic Animal Endocrinology (rok: 2020, tom: 73, strony: 106472), Wydawca: ELSEVIER
    Status:
    Published
    DOI:
    10.1016/j.domaniend.2020.106472 - link to the publication
  6. Wielokierunkowe działanie rezystyny w organizmie.
    Authors:
    Borsuk A., Biernat W., Zięba D.
    Academic press:
    Postępy Higieny i Medycyny Doświadczalnej (rok: 2018, tom: 72, strony: 327-337), Wydawca: Index Copernicus International
    Status:
    Published
    DOI:
    10.5604/01.3001.0011.8252 - link to the publication
  1. Hypothalamic and pituitary responses to resistin in sheep: Integration of resistin and leptin signaling involving SOCS-3 and LepRb.
    Authors:
    Zięba D.A., Biernat W., Szczęsna M., Kirsz K.
    Conference:
    American Society of Animal Science Conference (rok: 2019, ), Wydawca: American Society of Animal Science
    Data:
    konferencja 8-12 lipca
    Status:
    Published
  2. The effect of nutritional status on resistin's mediated leptin insensitivity in sheep.
    Authors:
    Biernat W., Szczęsna M., Kirsz K. Zięba-Przybylska D.A.
    Conference:
    The 5th Winter Workshop of the Society for Biology of Reproduction Central and Local Regulation of Reproductive Process" (rok: 2019, ), Wydawca: Towarzystwo Biologii Rozrodu
    Data:
    konferencja 13-15 luty
    Status:
    Published
  3. Is resistin engaged in the regulation of seasonality of reproduction in sheep?
    Authors:
    Zięba D.A., Biernat W., Kirsz K., Szczęsna M
    Conference:
    51st SSR Annual Meeting: Pathways to Discovery: Signals for Reproduction, Development, and Longevity". (rok: 2018, ), Wydawca: Society for the Study of Reproduction
    Data:
    konferencja 10-13 lipca
    Status:
    Published
  4. Resistin acts as a link between reproduction and energy metabolism in sheep.
    Authors:
    Zięba D.A., Biernat W., Szczęsna M., Kirsz
    Conference:
    10th International Ruminant Reproduction Symposium (IRRS 2018) (rok: 2018, ), Wydawca: Animal Reproduction. Brazilian College of Animal Reproduction.
    Data:
    konferencja 16-20 września
    Status:
    Published
  5. Resistin regulates prolactin concentration from the ovine adenohypophysis depending on season.
    Authors:
    Szczęsna M., Biernat W., Kirsz K., Zięba D.A.
    Conference:
    10th International Ruminant Reproduction (IRRS 2018) (rok: 2018, ), Wydawca: Animal Reproduction. Brazilian College of Animal Reproduction
    Data:
    konferencja 16-20 września
    Status:
    Published
  6. The involvement of resistin in the regulation of gonadotropin secretion in sheep.
    Authors:
    Kirsz K., Biernat W., Szczęsna M., Zięba D.A
    Conference:
    10th International Ruminant Reproduction Symposium (IRRS 2018) (rok: 2018, ), Wydawca: Animal Reproduction. Brazilian College of Animal Reproduction.
    Data:
    konferencja 16-20 września
    Status:
    Published

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