Application of morphological engineering techniques in the submerged cultures of filamentous fungi

2015/19/B/ST8/02115

Keywords

Descriptors

  • ST8_1: Inżynieria chemiczna, chemia techniczna, inżynieria środowiska, inżynieria sanitarna, inżynieria procesowa
  • ST8_13: Inne zagadnienia pokrewne

Panel

ST8 – Production and processes engineering: modelling, product design, process design and control, construction methods and engineering, power units and systems

Host institution

Politechnika Łódzka, Wydział Inżynierii Procesowej i Ochrony Środowiska

Voivodeship: łódzkie

Other projects carried out by the institution »

Principal investigator (from the host institution)

prof. Marcin Bizukojć

Number of co-investigators in the project: 4

Call

OPUS 10 – announced on 2015-09-15

Amount awarded
532 800 PLN
Project start date
2016-06-14
Project end date
2019-06-13
Project duration
36 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Mikroskop świetlny z kamerą i oprogramowanie do cyfrowej analizy obrazu. Cost: 180 000 PLN

Information in the final report

Publication in academic press/journals (8)

  1. Bioprocess-related, morphological and bioinformatic perspectives on the biosynthesis of secondary metabolites produced by Penicillium solitum.

    Authors:
    Boruta T., Przerywacz P., Ryngajłło M., Bizukojć M.
    Academic press:
    Process Biochemistry (year: 2018, volume: 68, pages: 46377), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.procbio.2018.02.023 – link to the publication
  2. Techniki inżynierii morfologicznej dla zwiększania wydajności tworzenia metabolitów przez grzyby strzępkowe w hodowlach wgłębnych

    Authors:
    Marcin Bizukojć
    Academic press:
    Przemysł Chemiczny (year: 2017, volume: 96/3, pages: 645-649), Publisher: SIGMA NOT
    Status:
    Published
  3. Application of aluminum oxide nanoparticles in Aspergillus terreus cultivations: evaluating the effects on lovastatin production and fungal morphology

    Authors:
    Tomasz Boruta, Marcin Bizukojć
    Academic press:
    BioMed Research International (year: 2019, volume: ID 5832496, pages: 46033), Publisher: Hindawi
    Status:
    Published
    DOI:
    10.1155/2019/5832496 – link to the publication
  4. Morphological evolution of various fungal species in the presence and absence of aluminum oxide microparticles: Comparative and quantitative insights into microparticle-enhanced cultivation (MPEC)

    Authors:
    Anna Kowalska, Tomasz Boruta, Marcin Bizukojć
    Academic press:
    MicrobiologyOpen (year: 2018, volume: 7(5), pages: e00603), Publisher: Wiley
    Status:
    Published
    DOI:
    10.1002/mbo3.603 – link to the publication
  5. Porównanie form morfologicznych grzybni A. terreus i M. racemosus w hodowlach wgłębnych

    Authors:
    Anna Kowalska, Tomasz Boruta, Marcin Bizukojć
    Academic press:
    Acta Scientarum Polonorum Biotechnologia (year: 2018, volume: 17(3), pages: 43-50), Publisher: Uniwersytet Przyrodniczy we Wrocławiu
    Status:
    Published
    DOI:
    10.30825/5.biot.65.2018.17.3 – link to the publication
  6. Performance of fungal microparticle-enhanced cultivations in stirred tank bioreactors depends on species and number of process stages.

    Authors:
    Anna Kowalska, Tomasz Boruta, Marcin Bizukojć
    Academic press:
    Biochemical Engineering Journal (year: 2020, volume: 161, pages: 107696), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bej.2020.107696 – link to the publication
  7. Kinetic model to describe the morphological evolution of filamentous fungi during their early stages of growth in the standard submerged and microparticle-enhanced cultivations.

    Authors:
    Anna Kowalska, Tomasz Boruta, Marcin Bizukojć
    Academic press:
    Engineering in Life Sciences (year: 2019, volume: 19, pages: 557-574), Publisher: Wiley
    Status:
    Published
    DOI:
    10.1002/elsc.201900013 – link to the publication
  8. Exploring the extremes: applying high concentration of yeast extract leads to drastic morphological changes and elimination of (+)-geodin and asterric acid production in Aspergillus terreus submerged cultures

    Authors:
    Tomasz Boruta, Adrianna Górnicka, Iwona Grzybowska, Ida Stefaniak, Marcin Bizukojć
    Academic press:
    Biotechnology Letters (year: 2021, volume: 43, pages: 61-71), Publisher: Springer
    Status:
    Published
    DOI:
    10.1007/s10529-020-03018-5 – link to the publication

Articles in post-conference publications (3)

  1. Production of secondary metabolites by Aspergillus terreus cocultivated with Chaetomium globosum under submerged conditions

    Authors:
    Tomasz Boruta, Iwona Milczarek, Marcin Bizukojć
    Conference:
    ECB18 18th European Congress on Biotechnology, Genewa, Szwajcaria (year: 2018, pages: S131), Publisher: Elsevier, Abstracts/New Biotechnology
    Date:
    conference 1-4 lipca 2018
    Status:
    Published
  2. Kinetic model describing the early stages of morphological evolution of various filamentous fungi species

    Authors:
    Anna Kowalska, Tomasz Boruta, Marcin Bizukojć
    Conference:
    ECB18 18th European Congress on Biotechnology, Genewa, Szwajcaria (year: 2018, pages: S133), Publisher: Elsevier, Abstracts/New Biotechnology
    Date:
    conference 1-4 lipca 2018
    Status:
    Published
  3. Microparticle-enhanced cultivation of filamentous fungi – insight into the action of microparticles towards various fungal species

    Authors:
    Marcin Bizukojć, Anna Kowalska, Tomasz Boruta
    Conference:
    ECB18 18th Eurpean Congress on Biotechnology, Genewa, Szwajcaria (year: 2018, pages: S19), Publisher: Elsevier, Abstracts/New Biotechnology
    Date:
    conference 1-4 lipca 2018
    Status:
    Published

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