Endocytosis of AXL receptor and its role in AXL-mediated signaling.

2015/19/D/NZ3/03270

NZ3 – Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Voivodeship: mazowieckie

Number of co-investigators in the project: 3

SONATA 10 – announced on 2015-09-15

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Bemcentinib and gilteritinib inhibit cell growth and impair the endo-lysosomal and autophagy systems in an AXL-independent manner

Authors:
Daria Zdzalik-Bielecka, Kamila Kozik, Agata Poswiata, Kamil Jastrzebski, Marta Jakubik, Marta Miaczynska

Academic press:
Molecular Cancer Research (year: 2021, volume: brak, pages: brak), Publisher: American Association for Cancer Research (USA)

Status:
Published

DOI:
10.1158/1541-7786.MCR-21-0444 – link to the publication
The GAS6-AXL signaling pathway triggers actin remodeling that drives membrane ruffling, macropinocytosis, and cancer-cell invasion

Authors:
Daria Zdżalik-Bielecka, Agata Poświata, Kamila Kozik, Kamil Jastrzębski, Kay Oliver Schink, Marta Brewińska-Olchowik, Katarzyna Piwocka, Harald Stenmark, Marta Miączyńska

Academic press:
Proceedings of the National Academy of Sciences of the United States of America (PNAS) (year: 2021, volume: 118, pages: brak), Publisher: National Academy of Sciences (NAS)

Status:
Published

DOI:
10.1073/pnas.2024596118 – link to the publication

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