Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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Identification of new mutations predisposing to prostate cancer in the Polish population by means of next generation sequencing

2015/19/B/NZ2/02439

Keywords:

prostate cancer aethiology genetic susceptibility genes mutations high risk

Descriptors:

  • NZ5_1: Etiology of human diseases
  • NZ2_1: Molecular genetics
  • NZ2_11: Genetic epidemiology

Panel:

NZ2 - Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology

Host institution :

Pomorski Uniwersytet Medyczny w Szczecinie, Wydział Lekarsko-Biotechnologiczny i Medycyny Laboratoryjnej

woj. zachodniopomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Cezary Cybulski 

Number of co-investigators in the project: 6

Call: OPUS 10 - announced on 2015-09-15

Amount awarded: 1 720 440 PLN

Project start date (Y-m-d): 2016-08-31

Project end date (Y-m-d): 2022-08-30

Project duration:: 72 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (4)
  1. Do BARD1 mutations confer an elevated risk of prostate cancer?
    Authors:
    Stempa Klaudia, Wokołorczyk Dominika, Kluźniak Wojciech, Rogoża-Janiszewska Emilia, Malińska Karolina, Rudnicka Helena, Huzarski Tomasz, Gronwald Jacek, Gliniewicz Katarzyna, Dębniak Tadeusz, Jakubowska Anna, Lener Marcin, Tomiczek-Szwiec Joanna, Domagała Paweł, Suszyńska Malwina, Kozłowski Piotr, Kluz Tomasz, Naczk Mariusz, Lubiński Jan, Narod Steven A., Akbari Mohammad R., Cybulski Cezary
    Academic press:
    Cancers (rok: 2021, tom: vol. 13, nr 21, strony: 45304), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cancers13215464 - link to the publication
  2. Inherited NBN Mutations and Prostate Cancer Risk and Survival
    Authors:
    Rusak B, Kluźniak W, Wokołorczykv D, Stempa K, Kashyap A, Gronwald J, Huzarski T, Dębniak T, Jakubowska A, Masojć B, Akbari MR, Narodv SA, Lubiński J, Cybulski C.
    Academic press:
    Cancer Res Treat. (rok: 2019, tom: 51(3), strony: 1180-1187), Wydawca: the Korean Cancer Association
    Status:
    Published
    DOI:
    10.4143/crt.2018.532. - link to the publication
  3. PALB2 mutations and prostate cancer risk and survival
    Authors:
    Dominika Wokołorczyk, Wojciech Kluźniak, Klaudia Stempa, Bogna Rusak, Tomasz Huzarski, Jacek Gronwald, Katarzyna Gliniewicz, Aniruddh Kashyap, Sylwia Morawska, Tadeusz Dębniak, Anna Jakubowska, Marek Szwiec, Paweł Domagała, Jan Lubiński, Steven A. Narod, Mohammad R. Akbari, Cezary Cybulski
    Academic press:
    Br J Cancer (rok: 2021, tom: vol. 125, nr 4, strony: 569-575), Wydawca: Springer Nature's Nature Research
    Status:
    Published
    DOI:
    10.1038/s41416-021-01410-0 - link to the publication
  4. Mutations in ATM, NBN and BRCA2 predispose to aggressive prostate cancer in Poland
    Authors:
    Wokołorczyk D, Kluźniak W, Huzarski T, Gronwald J, Szymiczek A, Rusak B, Stempa K, Gliniewicz K, Kashyap A, Morawska S, Dębniak T, Jakubowska A, Szwiec M, Domagała P, Lubiński J, Narod SA, Akbari MR, Cybulski C
    Academic press:
    Int J Cancer (rok: 2020, tom: 147(10), strony: 2793-2800), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1002/ijc.33272 - link to the publication

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