How estrogens and EDCs affect immune response? The role of membrane and nuclear estrogen receptors and aromatase in the regulation of inflammatory response in fish.

2015/19/B/NZ6/00895

Keywords

Descriptors

  • NZ6_1: Odporność swoista i nieswoista
  • NZ6_3: Immunologia zwierząt
  • NZ6_8: Inne zagadnienia pokrewne

Panel

NZ6 – Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution

Uniwersytet Jagielloński, Wydział Biologii

Voivodeship: małopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

prof. Magdalena Katarzyna Chadzińska

Number of co-investigators in the project: 8

Call

OPUS 10 – announced on 2015-09-15

Amount awarded
761 200 PLN
Project start date
2016-07-22
Project end date
2020-01-21
Project duration
42 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Moduł pomiaru stężenia i czystości DNA/RNA.
  2. RQ-PCR. Cost: 130 000 PLN

Information in the final report

Publication in academic press/journals (7)

  1. Estrogen-dependent seasonal adaptations in the immune response of fish.

    Authors:
    Szwejser E, Verburg-van Kemenade BM, Maciuszek M, Chadzinska M.
    Academic press:
    Hormones and Behavior (year: 2017, volume: 88, pages: 15-24), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.yhbeh.2016.10.007 – link to the publication
  2. A role for CXC chemokines and their receptors in stress axis regulation of common carp

    Authors:
    Pijanowski L, Verburg-van Kemenade BML, Chadzinska M.
    Academic press:
    General and Comparative Endocrinology (year: 2019, volume: 280, pages: 194-199), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ygcen.2019.05.004 – link to the publication
  3. Effects of stress and cortisol on the polarization of carp macrophages.

    Authors:
    Maciuszek M, Rydz L, Świtakowska I, Verburg-van Kemenade BML, Chadzińska M
    Academic press:
    Fish & Shellfish Immunology (year: 2019, volume: 94, pages: 27-37), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.fsi.2019.08.064 – link to the publication
  4. Stress differentially affects the systemic and leukocyte estrogen network in common carp.

    Authors:
    Szwejser E, Pijanowski L, Maciuszek M, Ptak A, Wartalski K, Duda M, Segner H, Verburg-van Kemenade BML, Chadzinska M.
    Academic press:
    Fish & Shellfish Immunology (year: 2017, volume: 68, pages: 190-201), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.fsi.2017.07.011 – link to the publication
  5. 17β-estradiol affects the innate immune response in common carp

    Authors:
    Maciuszek M, Pijanowski L, Pekala-Safinska A, Verburg-van Kemenade BML, Chadzinska M
    Academic press:
    Fish Physiology and Biochemistry (year: 2020, volume: 46, pages: 1775-1794), Publisher: Springer
    Status:
    Published
    DOI:
    10.1007/s10695-020-00827-3 – link to the publication
  6. 17α-ethinylestradiol and 4-tert-octylphenol concurrently disrupt the immune response of common carp

    Authors:
    Maciuszek M, Pijanowski L, Pekala-Safinska A, Palichleb P, Błachut M, Verburg-van Kemenade BML, Chadzińska M
    Academic press:
    Fish & Shellfish Immunology (year: 2020, volume: 107, pages: 238-250), Publisher: Elsevier
    Status:
    Published
  7. Chemokine CXCb1 stimulates formation of NETs in trunk kidney neutrophils of common carp

    Authors:
    Pijanowski L, Kemenade BMLV, Chadzinska M.
    Academic press:
    Developmental and Comparative Immunology (year: 2020, volume: 103, pages: 103521), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.dci.2019.103521 – link to the publication

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Graphic design and implementation: Jakub Piotrowski