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Effect of neonatal exposure to endocrine active compounds on the ovarian function of adult pig - molecular and epigenetic aspects

2015/19/B/NZ9/00420

Keywords

Descriptors

  • NZ9_2: Naukowe podstawy zootechniki
  • NZ9_13: Inne zagadnienia pokrewne
  • NZ4_6: Endokrynologia

Panel

NZ9 – Fundamentals of applied life sciences and biotechnology: agricultural, forestry, horticulture, animal production and fishery, food and nutrition sciences, industrial biosciences, environmental biotechnology and remediation

Host institution

Uniwersytet Jagielloński, Wydział Biologii

Voivodeship: małopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr hab. Katarzyna Knapczyk-Stwora

Number of co-investigators in the project: 6

Call

OPUS 10 – announced on 2015-09-15

Amount awarded
549 480 PLN
Project start date
2016-07-08
Project end date
2020-07-07
Project duration
48 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Cieplarka laboratoryjna – parafiniarka. Cost: 20 000 PLN
  2. Program Geneious. Cost: 3 000 PLN
  3. Ręczny mechaniczny homogenizator tkanek. Cost: 7 000 PLN
  4. Urządzenie do magazynowania danych.
  5. Zestaw do półsuchego transferu Pierce™ Power Blotter. Cost: 12 000 PLN
  6. Zestaw komputerowy z oprogramowaniem.

Information in the final report

Publication in academic press/journals (6)

  1. Effect of neonatal exposure to endocrine-active compounds on plasma lipid and steroid concentrations, and morphology of luteal tissue in the adult pig

    Authors:
    Patrycja Witek, Malgorzata Grzesiak, Marek Koziorowski, Maria Slomczynska, Katarzyna Knapczyk- Stwora
    Academic press:
    Domestic Animal Endocrinology (year: 2020, volume: 70, pages: 106381: 1-6), Publisher: Elsevier Inc.
    Status:
    Published
    DOI:
    10.1016/j.domaniend.2019.07.009 – link to the publication

  2. Neonatal exposure to agonists and antagonists of sex steroid receptors induces changes in the expression of oocyte-derived growth factors and their receptors in ovarian follicles in gilts

    Authors:
    Katarzyna Knapczyk-Stwora, Malgorzata Grzesiak, Patrycja Witek, Malgorzata Duda, Marek Koziorowski, Maria Slomczynska
    Academic press:
    Theriogenology (year: 2019, volume: 134, pages: 42-52), Publisher: Elsevier Inc.
    Status:
    Published
    DOI:
    10.1016/j.theriogenology.2019.05.018 – link to the publication

  3. Effects of neonatal exposure to methoxychlor on corpus luteum in gilts: A transcriptomic analysis

    Authors:
    Patrycja Witek, Francisco J Enguita, Malgorzata Grzesiak, Marina C Costa, André Gabriel, Marek Koziorowski, Maria Slomczynska, Katarzyna Knapczyk-Stwora
    Academic press:
    Molecular Reproduction and Development (year: 2021, volume: 88, pages: 238-248), Publisher: Wiley (John Wiley & Sons)
    Status:
    Published
    DOI:
    10.1002/mrd.23463 – link to the publication

  4. Effect of neonatal exposure to endocrine-active compounds on epigenetic regulation of gene expression in corpus luteum of gilts

    Authors:
    Patrycja Witek, Małgorzata Grzesiak, Małgorzata Kotula-Balak, Marek Koziorowski, Maria Słomczyńska, Katarzyna Knapczyk-Stwora
    Academic press:
    Theriogenology (year: 2021, volume: 159, pages: 45-52), Publisher: Elsevier Inc.
    Status:
    Published
    DOI:
    10.1016/j.theriogenology.2020.10.010 – link to the publication

  5. A transcriptome approach evaluating effects of neonatal androgen and anti-androgen treatments on regulation of luteal function in sexually mature pigs

    Authors:
    Katarzyna Knapczyk-Stwora, Marina C. Costa, André Gabriel, Malgorzata Grzesiak, Magdalena Hubalewska-Mazgaj, Patrycja Witek, Marek Koziorowski, Maria Slomczynska
    Academic press:
    Animal Reproduction Science (year: 2020, volume: 212, pages: 106252: 1-12), Publisher: Elsevier B.V.
    Status:
    Published
    DOI:
    10.1016/j.anireprosci.2019.106252 – link to the publication

  6. Neonatal Exposure to Agonists and Antagonists of Sex Steroid Receptors Aects AMH and FSH Plasma Level and Their Receptors Expression in the Adult Pig Ovary

    Authors:
    Katarzyna Knapczyk-Stwora, Malgorzata Grzesiak, Patrycja Witek, Malgorzata Duda , Marek Koziorowski, Maria Slomczynska
    Academic press:
    Animals (year: 2020, volume: 10, pages: 12: 1-14), Publisher: MDPI AG
    Status:
    Published
    DOI:
    10.3390/ani10010012 – link to the publication

Articles in post-conference publications (4)

  1. Effect of neonatal exposure to sex steroid agonists and antagonists on steroidogenic function of porcine corpus luteum

    Authors:
    Katarzyna Knapczyk-Stwora, Malgorzata Grzesiak, Maria Slomczynska, Slawomir Nowak, Marek Koziorowski
    Conference:
    18th International Congress of Endocrinology 58rd SEMDSA Congress (year: 2018, pages: 23(3), 2019 Supplement: S134-S135), Publisher: Journal of Endocrinology, Metabolism and Diabetes South Africa (JEMDSA)
    Date:
    conference 1-4 grudnia 2018
    Status:
    Published

  2. Effect of estrogen imbalance during neonatal period on the expression of receptors for GDF9 and BMP15 in small antral follicle in pig

    Authors:
    Malgorzata Grzesiak, Maria Slomczynska, Marek Koziorowski, Katarzyna Knapczyk-Stwora
    Conference:
    21st Annual ESDAR Conference 2017 (year: 2017, pages: 52(Suppl. 3): 93), Publisher: Reproduction in Domestic Animals
    Date:
    conference 24-26 Sierpień 2017
    Status:
    Published

  3. MicroRNA profiling in corpora lutea of pigs exposed to endocrine active chemicals during neonatal period

    Authors:
    Katarzyna Knapczyk-Stwora, Francisco J. Enguita, Marina C Costa, Malgorzata Grzesiak, Magdalena Hubalewska-Mazgaj, Maria Slomczynska, Marek Koziorowski
    Conference:
    18th International Congress of Endocrinology 53rd SEMDSA Congress (year: 2018, pages: 23(3), 2019 Supplement: S134), Publisher: Journal of Endocrinology, Metabolism and Diabetes South Africa (JEMDSA)
    Date:
    conference 1-4 grudnia 2018
    Status:
    Published

  4. Does neonatal exposure to estrogenic/anti-estrogenic agents affect the expression of oocyte-derived factors and their receptors in preantral follicles of adult swine?

    Authors:
    Małgorzata Grzesiak, Maria Słomczyńska, Karolina Putera, Małgorzata Duda, Marek Koziorowski, Katarzyna Knapczyk-Stwora
    Conference:
    51. Sympozjum Polskiego Towarzystwa Histochemików i Cytochemików (year: 2017, pages: 59), Publisher: Polskie Towarzystwo Histochemików i Cytochemików
    Date:
    conference 12-14 września 2017
    Status:
    Published

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