Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Functional-Group-Activated Polyenes in Asymmetric Organocatalysis

2015/18/E/ST5/00309

Keywords:

asymmetric synthesis organocatalysis polyenes remote functionalizations

Descriptors:

  • ST5_23:
  • ST5_22:

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Politechnika Łódzka, Wydział Chemiczny

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Łukasz Albrecht 

Number of co-investigators in the project: 5

Call: SONATA BIS 5 - announced on 2015-06-15

Amount awarded: 1 998 400 PLN

Project start date (Y-m-d): 2016-05-13

Project end date (Y-m-d): 2022-05-12

Project duration:: 72 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Pompa próżniowa (7 000 PLN)
  2. Autosampler dla spektrometru Bruker 700 MHz (100 000 PLN)
  3. Kolumny HPLC z chiralnym wypełnieniem (2 szt.) (20 000 PLN)
  4. Membranowa pompa próżniowa z kontrolerem próżni (16 000 PLN)
  5. Wyparka obrotowa.
  6. Autoklaw (20 000 PLN)
  7. Pompa próżniowa.
  8. System do chromatografii flash (220 000 PLN)
  9. Wyparka obrotowa (2 szt.) (17 000 PLN)

Information in the final report

  • Publication in academic press/journals (14)
  1. Vinylogous Nucleophiles Bearing the Endocyclic Double Bond in the Allylic Alkylation with Morita-Baylis-Hillman Carbonates
    Authors:
    Kowalczyk, D.; Albrecht, Ł.
    Academic press:
    Advanced Synthesis & Catalysis (rok: 2018, tom: 360, strony: 406-410), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1002/adsc.201701185 - link to the publication
  2. 2‑Substituted 1,4-Naphthoquinones in [6 + 4]-Cycloaddition with 8,8-Dicyanoheptafulvene
    Authors:
    Marta Romaniszyn, Katarzyna Gronowska, Łukasz Albrecht
    Academic press:
    The Journal of Organic Chemistry (rok: 2019, tom: 84, strony: 9929−9936), Wydawca: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acs.joc.9b01091 - link to the publication
  3. Site-Selective and Enantioselective α,β,γ-Functionalization of 5-Alkylidenefuran-2(5H)-ones: A Route to Polycyclic γ-Lactones
    Authors:
    Skrzyńska A., Frankowski S., Moczulski, M., Drelich P., Albrecht, Ł.
    Academic press:
    Organic Letters (rok: 2019, tom: 21, strony: 1248–1252), Wydawca: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acs.orglett.8b03796 - link to the publication
  4. Allylic–Allylic Alkylation with 3,5-Dimethyl-4-nitroisoxazole: A Route to Dicarboxylic Acid Derivatives
    Authors:
    Dorota Kowalczyk-Dworak, Marcin Kwit, Łukasz Albrecht
    Academic press:
    The Journal of Organic Chemistry (rok: 2020, tom: 85, strony: 2938-2944), Wydawca: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acs.joc.9b02530 - link to the publication
  5. Brønsted-base-catalyzed Remote Cascade Reactivity of 2,4-Dienones - Asymmetric Synthesis of Tetrahydrothiophenes
    Authors:
    Przydacz, A.; Kowalczyk, R.; Albrecht, Ł.
    Academic press:
    Organic & Biomolecular Chemistry (rok: 2017, tom: 15, strony: 9566-9569), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/c7ob02397a - link to the publication
  6. Synthesis of γ,γ‐Disubstituted Butenolides through a Doubly Vinylogous Organocatalytic Cycloaddition
    Authors:
    Skrzyńska A., Drelich P., Frankowski S., Albrecht, Ł.
    Academic press:
    Chemistry - A European Journal (rok: 2018, tom: 24, strony: 16543–16547), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1002/chem.201804650 - link to the publication
  7. The Game of Electrons: Organocatalytic Higher‐Order Cycloadditions Involving Fulvene‐ and Tropone‐Derived Systems
    Authors:
    Sebastian Frankowski, Marta Romaniszyn, Anna Skrzyńska, Łukasz Albrecht
    Academic press:
    Chemistry - A European Journal (rok: 2020, tom: 26, strony: 2120-2132), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1002/chem.201904157 - link to the publication
  8. Asymmetric vinylogous Michael addition of 5-substituted-furan-2(3H)-ones to an α,β-unsaturated-γ-lactam
    Authors:
    Marta Romaniszyn, Lesław Sieroń, Łukasz Albrecht
    Academic press:
    Organic & Biomolecular Chemistry (rok: 2020, tom: 18, strony: 8633-8637), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/D0OB01750G - link to the publication
  9. Hydroxyl-group-activated azomethine ylides in organocatalytic H-bond-assisted 1,3-dipolar cycloadditions and beyond
    Authors:
    Artur Przydacz, Jan Bojanowski, Anna Albrecht, Łukasz Albrecht
    Academic press:
    Organic & Biomolecular Chemistry (rok: 2021, tom: 19, strony: 3075-3086), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/D0OB02380A - link to the publication
  10. Inverting the reactivity of troponoid systems in enantioselective higher-order cycloaddition
    Authors:
    Sebastian Frankowski, Anna Skrzyńska, Łukasz Albrecht
    Academic press:
    Chemical Communications (rok: 2019, tom: 55, strony: 11675-11678), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/c9cc05638f - link to the publication
  11. Remote Functionalization of 4-(Alk-1-en-1-yl)-3-Cyanocoumarins via the Asymmetric Organocatalytic 1,6-Addition
    Authors:
    Marta Romaniszyn, Katarzyna Gronowska, Łukasz Albrecht
    Academic press:
    Advanced Synthesis and Catalysis (rok: 2021, tom: 363, strony: 5116 - 5121), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1002/adsc.202100660 - link to the publication
  12. Organocatalytic asymmetric approach to γ,δ-functionalization of 3-cyano-4-styrylcoumarins via bifunctional catalysis
    Authors:
    Marta Romaniszyn, Anna Skrzyńska, Joanna Dybowska, Łukasz Albrecht
    Academic press:
    Organic Letters (rok: 2022, tom: 24, strony: 7722–7726), Wydawca: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acs.orglett.2c02836 - link to the publication
  13. The Application of 2‑Benzyl-1,4-naphthoquinones as Pronucleophiles in Aminocatalytic Synthesis of Tricyclic Derivatives
    Authors:
    Skrzyńska, A.; Romaniszyn, M.; Pomikło, D.; Albrecht, Ł.
    Academic press:
    The Journal of Organic Chemistry (rok: 2018, tom: 83, strony: 5019-5026), Wydawca: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acs.joc.8b00170 - link to the publication
  14. Breaking Aromaticity with Aminocatalysis: A Convenient Strategy for Asymmetric Synthesis
    Authors:
    Przydacz A., Skrzyńska A., Albrecht Ł.
    Academic press:
    Angewandte Chemie International Edition (rok: 2019, tom: 58, strony: 63–73), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1002/anie.201808197 - link to the publication

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