Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Dissection of putative transcriptional regulators from Pseudomonas aeruginosa proteome dependent on ParA/ParB using systems biology tools.

2015/18/E/NZ2/00675

Keywords:

transcriptional regulator gene expression regulation regulatory network ParA/ParB regulon Pseudomonas aeruginosa systems biology

Descriptors:

  • NZ2_1: Molecular genetics
  • NZ2_2: Genomics, transcriptomics, epigenomics
  • NZ2_9: Systems biology

Panel:

NZ2 - Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology

Host institution :

Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Aneta Bartosik 

Number of co-investigators in the project: 4

Call: SONATA BIS 5 - announced on 2015-06-15

Amount awarded: 1 518 680 PLN

Project start date (Y-m-d): 2016-04-20

Project end date (Y-m-d): 2022-04-19

Project duration:: 72 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Zamrażarka do ultra niskich temperatur (-80oC) (50 000 PLN)
  2. Komputery z oprogramowaniem (15 000 PLN)
  3. Wielodetekcyjny czytnik płytek 6-384-dołkowych umożliwiający pomiar absorbancji, fluorescencji i luminescencji wraz z oprogramowaniem. Dodatkowo kompatybilna płytka do pomiaru mikroilości DNA lub RNA przy 260 nm. (120 000 PLN)

Information in the final report

  • Publication in academic press/journals (6)
  • Articles in post-conference publications (7)
  1. The AraC-Type Transcriptional Regulator GliR (PA3027) Activates Genes of Glycerolipid Metabolism in Pseudomonas aeruginosa
    Authors:
    Karolina Kotecka , Adam Kawalek , Kamil Kobylecki and Aneta Agnieszka Bartosik
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 2021, 22, 5066, strony: 5066), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms22105066 - link to the publication
  2. The Lrp/AsnC-Type Regulator PA2577 Controls the EamA-like Transporter Gene PA2576 in Pseudomonas aeruginosa
    Authors:
    Magdalena Modrzejewska, Adam Kawalek, Aneta Agnieszka Bartosik
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 2021, 22, 13340, strony: 13340), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms222413340 - link to the publication
  3. Genome sequence of Pseudomonas aeruginosa PAO1161, a PAO1 derivative with the ICEPae1161 integrative and conjugative element
    Authors:
    Adam Kawalek, Karolina Kotecka, Magdalena Modrzejewska, Jan Gawor, Grazyna Jagura-Burdzy and Aneta Agnieszka Bartosik
    Academic press:
    BMC Genomics (rok: 2020, tom: 21, strony: (2020) 21:14), Wydawca: BMC part of Springer Nature (BioMed Central Ltd.)
    Status:
    Published
    DOI:
    10.1186/s12864-019-6378-6 - link to the publication
  4. Interaction of ArmZ with the DNA-Binding Domain of MexZ Induces Expression of mexXY Multidrug Efflux Pump Genes and Antimicrobial Resistance in Pseudomonas aeruginosa
    Authors:
    Adam Kawalek, Magdalena Modrzejewska, Bartlomiej Zieniuk, Aneta Agnieszka Bartosik, Grazyna Jagura-Burdzy
    Academic press:
    Antimicrobial Agents and Chemotherapy (rok: 2019, tom: 63, strony: 63:e01199-19), Wydawca: American Society for Microbiology
    Status:
    Published
    DOI:
    10.1128/AAC.01199-19 - link to the publication
  5. The LysR-Type Transcriptional Regulator BsrA (PA2121) Controls Vital Metabolic Pathways in Pseudomonas aeruginosa
    Authors:
    Magdalena Modrzejewska,a Adam Kawalek,a Aneta Agnieszka Bartosika
    Academic press:
    mSystems (rok: 2021, tom: 6:e00015-21, strony: e00015-21), Wydawca: ASM
    Status:
    Published
    DOI:
    10.1128/mSystems.00015-21 - link to the publication
  6. The MarR-Type Regulator PA3458 Is Involved in Osmoadaptation Control in Pseudomonas aeruginosa
    Authors:
    Karolina Kotecka , Adam Kawalek , Kamil Kobylecki, Aneta Agnieszka Bartosik
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 2021, 22, 3982, strony: 3982), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms22083982 - link to the publication
  1. Analysis of three putative transcriptional regulators PA1196, PA2121 and PA2577 from Pseudomonas aeruginosa proteome
    Authors:
    M. Modrzejewska, A.A. Bartosik
    Conference:
    7th Congress of European Microbiologists (FEMS), Valencia, Spain (rok: 2017, ), Wydawca: 7th Congress of European Microbiologists (FEMS)
    Data:
    konferencja 9-13 July 2017
    Status:
    Published
  2. Studies on PA3027 – the AraC family transcriptional activator
    Authors:
    KOTECKA K., KAWAŁEK A., BARTOSIK A.A.
    Conference:
    International Biennial Conference Pseudomonas 2019, Kuala Lumpur, Malaysia, 22-26 July 2019 (rok: 2019, ), Wydawca: Pseudomonas 2019
    Data:
    konferencja 2019-07-22-26
    Status:
    Published
  3. Towards survival – logarithmic versus stationary phase studies on Pseudomonas aeruginosa
    Authors:
    BARTOSIK A.A., KOTECKA K., MODRZEJEWSKA M., KAWAŁEK A., JAGURA-BURDZY G.
    Conference:
    International Biennial Conference Pseudomonas 2019, Kuala Lumpur, Malaysia, 22-26 July 2019 (rok: 2019, ), Wydawca: Pseudomonas 2019
    Data:
    konferencja 2019-07-22-26
    Status:
    Published
  4. Preliminary functional characterization of putative transcriptional regulators PA3027, PA3458 and PA3973 from Pseudomonas aeruginosa
    Authors:
    K. Kotecka, A.A. Bartosik
    Conference:
    7th Congress of European Microbiologists (FEMS),Valencia, Spain (rok: 2017, ), Wydawca: 7th Congress of European Microbiologists (FEMS)
    Data:
    konferencja 9-13 July 2017
    Status:
    Published
  5. Characterization of transcriptional regulator PA3458 from Pseudomonas aeruginosa
    Authors:
    KOTECKA K., KAWAŁEK A., BARTOSIK A.A.
    Conference:
    8th Congress of European Microbiologists (FEMS), Glasgow, Scotland, 7-11 July 2019 (rok: 2019, ), Wydawca: FEMS
    Data:
    konferencja 2019-07-07-11
    Status:
    Published
  6. Functional characterization of TetR-like transcriptional regulator PA3973 from Pseudomonas aeruginosa
    Authors:
    Kotecka Karolina, Kawalek Adam, Gawor Jan, Zuchniewicz Karolina, Gromadka Robert, Bartosik Aneta Agnieszka
    Conference:
    International Biennial Conference Pseudomonas 2022, Atlanta, USA (rok: 2022, ), Wydawca: Pseudomonas 2022
    Data:
    konferencja 2022-04-18_23
    Status:
    Published
  7. Studies on PA2121 - a LysR-type transcriptional regulator from Pseudomonas aeruginosa
    Authors:
    MODRZEJEWSKA M., KAWAŁEK A., BARTOSIK A.A.
    Conference:
    8th Congress of European Microbiologists, Glasgow, Scotland (rok: 2019, ), Wydawca: FEMS
    Data:
    konferencja 2019-07-07-11
    Status:
    Published

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