Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Look at the mechanism of ovarian cancer cells response to adenine nucleosides modified with metallacarborane clusters with prospective anti-proliferative and pro-apoptotic activity

2015/17/B/NZ3/03764

Keywords:

ovarian cancer cells adenine nucleosides carborane clusters metallacarborane

Descriptors:

  • NZ3_1: Cell biology

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Instytut Biologii Medycznej PAN

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Katarzyna Bednarska 

Number of co-investigators in the project: 5

Call: OPUS 9 - announced on 2015-03-16

Amount awarded: 698 400 PLN

Project start date (Y-m-d): 2016-02-22

Project end date (Y-m-d): 2020-02-21

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (2)
  1. Adenosine Analogues as Opposite Modulators of the Cisplatin Resistance of Ovarian Cancer Cells
    Authors:
    Katarzyna Bednarska-Szczepaniak, Damian Krzyżanowski, Magdalena Klinka, Marek Nowak
    Academic press:
    Anti-Cancer Agents in Medicinal Chemistry (rok: 2019, tom: 19, strony: 473-486), Wydawca: Bentham Science Publishers
    Status:
    Published
    DOI:
    10.2174/1871520619666190118113201 - link to the publication
  2. Interaction of Adenosine, Modified Using Carborane Clusters, with Ovarian Cancer Cells: A New Anticancer Approach against Chemoresistance
    Authors:
    Katarzyna Bednarska-Szczepaniak, Ewelina Przelazły, Katarzyna Dominika Kania, Marzena Szwed, Miroslava Litecka, Bohumír Grűner, Zbigniew J. Leśnikowski
    Academic press:
    Cancers (rok: 2021, tom: 13(15), strony: 3855), Wydawca: MDPI, Basel, Switzerland
    Status:
    Published
    DOI:
    10.3390/cancers13153855 - link to the publication