Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Molecular determinants of Epithelial-Mesenchymal Transition in Cancer Cells

2015/17/B/NZ1/01777

Keywords:

differentiation gene regulation heritability development migration fate

Descriptors:

  • NZ1_1: Molecular biology
  • NZ1_5: Genetic engineering

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Uniwersytet Medyczny w Lublinie, Wydział Lekarski

woj. lubelskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Adolfo Rivero Muller 

Number of co-investigators in the project: 3

Call: OPUS 9 - announced on 2015-03-16

Amount awarded: 1 151 720 PLN

Project start date (Y-m-d): 2016-03-17

Project end date (Y-m-d): 2020-02-16

Project duration:: 47 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Aparat do elektroforezy MULTI SUB.
  2. Zamrażarka laboratoryjna.
  3. Elektroporator do bakterii (14 200 PLN)
  4. Transiluminator LED do analizy DNA (2 800 PLN)

Information in the final report

  • Publication in academic press/journals (9)
  1. Genetically engineered lung cancer cells for analyzing epithelial-mesenchymal transition.
    Authors:
    Michał Kiełbus, Jakub Czapiński, Joanna Kałafut, Justyna Woś, Andrzej Stepulak, Adolfo Rivero-Müller
    Academic press:
    Cells (rok: 2019, tom: 8 (12), strony: 45308), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cells8121644 - link to the publication
  2. Optogenetic control of NOTCH1 signaling
    Authors:
    Joanna Kałafut, Jakub Czapiński, Alicja Przybyszewska-Podstawka, Arkadiusz Czerwonka, Cecilia Sahlgren, Adolfo Rivero-Müller
    Academic press:
    Cell Communication and Signaling (rok: 2022, tom: 20, strony: 67), Wydawca: Cell Communication and Signaling
    Status:
    Published
    DOI:
    10.1186/s12964-022-00885-5 - link to the publication
  3. An Improved Vector System for Homogeneous and Stable Gene Regulation
    Authors:
    Michalec-Wawiórka B, Czapiński J, Filipek K, Rulak P, Czerwonka A, Tchórzewski M, Rivero-Müller A.
    Academic press:
    Int J Mol Sci. (rok: 2021, tom: 22, strony: 5206), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms22105206 - link to the publication
  4. Histone deacetylase inhibitors reinforce the phenotypical markers of breast epithelial or mesenchymal cancer cells but inhibit their migratory properties.
    Authors:
    Anna Wawruszak, Ewelina Gumbarewicz, Estera Okoń, Witold Jeleniewicz, Jakub Czapiński, Marta Hałasa, Karolina Okła, Jolanta Smok-Kalwat, Artur Bocian, Adolfo Rivero-Muller, Andrzej Stepulak
    Academic press:
    Cancer Management and Research (rok: 2019, tom: 11, strony: 8345-8358), Wydawca: Dove Press Ltd
    Status:
    Published
    DOI:
    10.2147/CMAR.S210029 - link to the publication
  5. How to Train a Cell–Cutting-Edge Molecular Tools
    Authors:
    Jakub Czapiński, Michał Kiełbus, Joanna Kałafut, Michał Kos, Andrzej Stepulak, Adolfo Rivero-Müller
    Academic press:
    Frontiers in Chemistry (rok: 2017, tom: 5, strony: 0), Wydawca: Frontiers in
    Status:
    Published
    DOI:
    10.3389/fchem.2017.00012 - link to the publication
  6. Histone deacetylase inhibitors and phenotypical transformation of cancer cells.
    Authors:
    Anna Wawruszak, Joanna Kałafut, Estera Okoń, Jakub Czapiński, Marta Hałasa, Alicja Przybyszewska, Paulina Miziak, Karolina Okła, Adolfo Rivero-Müller, Andrzej Stepulak
    Academic press:
    Cancers (rok: 2019, tom: 11 (2), strony: 45322), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cancers11020148 - link to the publication
  7. Optogenetics in cancer drug discovery.
    Authors:
    Kiełbus M, Czapiński J, Odrzywolski A, Stasiak G, Szymańska K, Kałafut J, Kos M, Giannopoulos K, Stepulak A, Rivero-Müller A
    Academic press:
    Expert Opinion on Drug Discovery (rok: 2018, tom: 15, strony: 45305), Wydawca: Taylor & Francis
    Status:
    Published
    DOI:
    10.1080/17460441.2018.1437138 - link to the publication
  8. Development of a Bioassay for Continuous Monitoring of TWIST1 Activity
    Authors:
    Czapiński, J.; Kałafut, J.; Przybyszewska-Podstawka, A.; Pawlicka, M.; Roszkowska, A.; Kiełbus, M.; Borkiewicz, L.; Dudziak, K.; Czerwonka, A.; Stepulak, A.; Rivero-Muller, A
    Academic press:
    Preprints (), Wydawca: Preprints
    Status:
    Submitted
    DOI:
    10.20944/preprints202103.0265.v1 - link to the publication
  9. Context Matters: NOTCH Signatures and Pathway in Cancer Progression and Metastasis
    Authors:
    Misiorek JO, Przybyszewska-Podstawka A, Kałafut J, Paziewska B, Rolle K, Rivero-Müller A, Nees M.
    Academic press:
    Cells (rok: 2021, tom: 10, strony: 94), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cells10010094 - link to the publication

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